克霉唑

价格	询价
包装	25Kg/Drum

最小起订量	25Kg
发货地	湖北
更新日期	2020-11-10

产品详情

中文名称:克霉唑	英文名称:Clotrimazole
CAS:23593-75-1	产品类别: boshan

Clotrimazole CAS 23593-75-1

CP/USP/BP/EP 25kg/DRUM

Clotrimazole structure	Common Name	Clotrimazole
	CAS Number	23593-75-1	Molecular Weight	344.837
	Density	1.1±0.1 g/cm3	Boiling Point	482.3±40.0 °C at 760 mmHg
	Molecular Formula	C22H17ClN2	Melting Point	147-149ºC
	MSDS	ChineseUSA	Flash Point	245.5±27.3 °C
	Symbol	GHS07	Signal Word	Warning

Use of Clotrimazole

Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor.Target: Antifungal; CYPClotrimazole (brand name Canesten or Lotrimin) is an antifungal medication commonly used in the treatment of fungal infections (of both humans and other animals) such as vaginal yeast infections, oral thrush, and ringworm. It is also used to treat athlete's foot and jock itch.It is commonly available as an over-the-counter substance in various dosage forms, such as a cream, and also (especially in the case of ear infection) as a combination medicine. It is also available as a troche or throat lozenge (prescription only). For ear infection, it is often applied in liquid form, as ear drops.The antimycotic drug clotrimazole inhibits the function of the gastric H,K-ATPase in a manner similar to that observed for the Na,K-ATPase. Because of the high hydrophobicity of the compound, the interaction between clotrimazole and the ion pump occurs at the membrane domain in the apolar core of the membrane. The enzymatic activity was inhibited with a half-saturating concentration of 5.2 microM. Various partial reactions of the pump cycle were analyzed with the electrochromic styryl dye RH421 that has been widely used to study the transport mechanism of P-type ATPases.

Properties
Articles158
Spectrum

Name	clotrimazole
Synonym	More Synonyms

Description	Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor.Target: Antifungal; CYPClotrimazole (brand name Canesten or Lotrimin) is an antifungal medication commonly used in the treatment of fungal infections (of both humans and other animals) such as vaginal yeast infections, oral thrush, and ringworm. It is also used to treat athlete's foot and jock itch.It is commonly available as an over-the-counter substance in various dosage forms, such as a cream, and also (especially in the case of ear infection) as a combination medicine. It is also available as a troche or throat lozenge (prescription only). For ear infection, it is often applied in liquid form, as ear drops.The antimycotic drug clotrimazole inhibits the function of the gastric H,K-ATPase in a manner similar to that observed for the Na,K-ATPase. Because of the high hydrophobicity of the compound, the interaction between clotrimazole and the ion pump occurs at the membrane domain in the apolar core of the membrane. The enzymatic activity was inhibited with a half-saturating concentration of 5.2 microM. Various partial reactions of the pump cycle were analyzed with the electrochromic styryl dye RH421 that has been widely used to study the transport mechanism of P-type ATPases.
Related Catalog	Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Infection
References	[1]. Sawyer PR, Clotrimazole: a review of its antifungal activity and therapeutic efficacy. Drugs. 1975;9(6):424-47. [2]. Witzke A, Inhibition of the gastric H,K-ATPase by clotrimazole. Biochemistry. 2010 Jun 1;49(21):4524-32.

Description

Related Catalog

Signaling Pathways >> Autophagy >> Autophagy

Signaling Pathways >> Anti-infection >> Fungal

Research Areas >> Infection

References

[1]. Sawyer PR, Clotrimazole: a review of its antifungal activity and therapeutic efficacy. Drugs. 1975;9(6):424-47.

[2]. Witzke A, Inhibition of the gastric H,K-ATPase by clotrimazole. Biochemistry. 2010 Jun 1;49(21):4524-32.

Density	1.1±0.1 g/cm3
Boiling Point	482.3±40.0 °C at 760 mmHg
Melting Point	147-149ºC
Molecular Formula	C22H17ClN2
Molecular Weight	344.837
Flash Point	245.5±27.3 °C
Exact Mass	344.108032
PSA	17.82000
LogP	5.44
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.617
Storage condition	Store at RT.
Water Solubility	Soluble in chloroform, DMSO, DMF and alcohols

CONTACT :

Tel & WhatsApp : +86 15972591113

QQ & WeChat: 577507723

Skype : smile491012

关键字： Clotrimazole;Clotrimazole;Clotrimazole;

公司简介

九州通是一家以西药、中药、器械为主要经营产品，以医疗机构、批发企业、零售药店为主要客户对象，并为客户提供信息、物流等各项增值服务的大型企业集团。公司立足于医药健康行业，是中国医药商业领域具有全国性网络的少数几家企业之一，于2010年11月2日在上海证券交易所挂牌上市（股票简称：九州通，证券代码：600998），公司连续多年位列中国医药商业企业第四位，领跑中国民营医药商业企业，2020年位列《财富》（中文版）500强第100位。九州通成立于1999年3月，总部位于湖北省武汉市。截止2020年9月30日，公司注册资本18.78亿元，总资产787.17亿元。实现营业收入803.20亿元，净利润21.41亿元，分别较上年同期增长9.46%和110.23％。扣除非经常性损益后归属于上市公司股东的净利润为12.52亿元，较上年同期增长45.12%。2019年公司实现营业收入994.97亿元，归属于上市公司股东的净利润17.81亿元，分别较上年同期增长14.19%和28.96%。员工两万五千余人。直营和加盟零售连锁药店1074家。

成立日期	1999-03-09 （26年）	注册资本	1877663513
员工人数	500人以上	年营业额	￥ 1亿以上
主营行业	医药中间体,原料药,兽药原料,维生素类	经营模式	贸易,工厂

九州通医药集团股份有限公司

非会员

公司成立：26年
注册资本：1877663513
企业类型：私营
主营产品：枸橼酸他莫昔芬克霉唑奋乃静硝酸异山梨酯盐酸美西律托吡卡胺
公司地址：号汉阳区龙阳大道特

进入店铺

询盘

店内推荐

枸橼酸他莫昔芬

询价

奋乃静

询价

硝酸异山梨酯

询价

克霉唑相关厂家报价

产品名称	价格		公司名称	报价日期
专注芥末粉泡菜腌渍生肉调味品等	询价	VIP1年	武汉吉业升化工有限公司	2024-08-13
低酯果胶生产厂家	￥85	VIP5年	南京松冠生物科技有限公司	2024-08-12
克霉唑（中间体）—23593-75-1	￥419	VIP3年	湖北魏氏化学试剂股份有限公司	2024-08-12
克霉唑，三苯氯甲咪唑	询价	VIP5年	湖北威德利化学试剂有限公司	2024-08-12
克霉唑	￥2000	VIP12年	湖北威德利化学科技有限公司	2024-08-12
克霉唑;23593-75-1	询价	VIP2年	武汉鼎程生科化学试剂有限公司	2024-08-12
克霉唑	￥800	VIP4年	武汉鼎信通药业有限公司	2024-08-12
芥末粉泡菜腌渍生肉调味品等	￥25	VIP1年	武汉吉业升化工有限公司	2024-08-12
芥末粉泡菜腌渍	询价	VIP1年	武汉吉业升化工有限公司	2024-08-12
克霉唑	询价	VIP5年	武汉鼎信通药业有限公司	2024-08-12

内容声明:
以上所展示的信息由商家自行提供，内容的真实性、准确性和合法性由发布商家负责。商家发布价格指该商品的参考价格，并非原价，该价格可能随着市场变化，或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格，请咨询商家，以实际成交价格为准。请意识到互联网交易中的风险是客观存在的

克霉唑

产品详情

Use of Clotrimazole

Names

Clotrimazole Biological Activity

Chemical & Physical Properties

公司简介

店内推荐

克霉唑相关厂家报价