Isoxazole
Isoxazole
- CAS:
- 288-14-2
- MF:
- C3H3NO
- MW:
- 69.06
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Company Type
Properties
- Melting point:
- -67.1°C
- Boiling point:
- 93-95 °C(lit.)
- Density
- 1.078 g/mL at 25 °C(lit.)
- vapor density
- 2.4 (vs air)
- refractive index
- n
20/D 1.427(lit.)
- Flash point:
- 48 °F
- storage temp.
- 2-8°C
- solubility
- 167g/l
- pka
- -2.0(at 25℃)
- form
- clear liquid
- color
- Colorless to Light yellow
- BRN
- 103773
- InChIKey
- CTAPFRYPJLPFDF-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS02
- Signal word
- Danger
- Hazard statements
- H225
- Precautionary statements
- P210
- Hazard Codes
- F,Xi
- Risk Statements
- 11
- Safety Statements
- 16-23/33-33-29-7/9
- RIDADR
- UN 1993 3/PG 2
- WGK Germany
- 3
- F
- 10
- Hazard Note
- Highly Flammable
- TSCA
- Yes
- HazardClass
- 3
- PackingGroup
- II
- HS Code
- 29349990
Use
As an important class of heterocycles, isoxazole is a five membered heterocyclic compound with various pharmacological actions, which is found in some natural products, such as ibotenic acid. It is used in the formation of the basis for a number of drugs, such as the COX-2 inhibitor valdecoxib and anti-inflammatory drugs. Isoxazoles are largely applied in the area of pharmaceuticals and therapeutics, including insecticidal, antibacterial, antibiotic, antitumour, antifungal, antituberculosis, anticancer and ulcerogenic. Besides, it has a great effect on reducing blood glucose, eliminating pain, resisting inflammation, killing harmful bacteria, controlling and reducing the risk of HIV. The isoxazole ring is an essential pharmacophore in modern drug discovery. Some beta-lactamase-resistant antibiotics contain an isoxazole group, including cloxacillin, dicloxacillin, flucloxacillin, and the isoxazole group is also found in some steroid drug such as danazol.
23 India supplier list of "Isoxazole"
- Product Name:ISOXAZOLE
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Isoxazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Isoxazole, 95%
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Isoxazole
- Products Intro:Brand:sigma aldrich | Product Number:151637 | Purity:99%
- Company Type: Trader
- Country/Region: INDIA