1,2,3-Trichlorobenzene
Product identifier
- Product name: 1,2,3-Trichlorobenzene
- CBnumber: CB7854514
- CAS: 87-61-6
- EINECS Number: 201-757-1
- Synonyms: 1,2,3-TRICHLOROBENZENE,Benzene,1,2,3-trichloro-
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin sensitization, Category 1
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
Label elements
Pictogram(s)
- Signal wordDanger
H225 Highly Flammable liquid and vapour
H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H370 Causes damage to organs
H401 Toxic to aquatic life
H411 Toxic to aquatic life with long lasting effects
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P330 Rinse mouth.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: 1,2,3-Trichlorobenzene
- Synonyms: 1,2,3-TRICHLOROBENZENE,Benzene,1,2,3-trichloro-
- CAS: 87-61-6
- EC number: 201-757-1
- MF: C6H3Cl3
- MW: 181.45
Description of first aid measures
If inhaledFresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .
Most important symptoms and effects, both acute and delayed
Inhalation may cause irritation of respiratory tract. Irritating to the eyes. May redden skin on contact. Ingestion may cause liver damage. (USCG, 1999)
Indication of any immediate medical attention and special treatment needed
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Aromatic hydrocarbons and related compounds
Extinguishing media
Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may spread fire. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide.
Specific Hazards Arising from the Chemical
Special Hazards of Combustion Products: May emit toxic hydrogen chloride and phosgene gases in fire. Behavior in Fire: Decomposes to form hydrogen chloride and phosgene gases in fire. (USCG, 1999)
Advice for firefighters
Use water spray, dry powder, foam, carbon dioxide.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Personal protection: P2 filter respirator for harmful particles. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: P2 filter respirator for harmful particles. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a POTW is acceptable only after review by the governing authority. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must meet Hazardous Material Criteria for disposal.
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from strong oxidants. Keep in a well-ventilated room.
Control parameters
Occupational Exposure limit valuesMAK: 38 mg/m3, 5 ppm; peak limitation category: II(2); skin absorption (H); pregnancy risk group: C
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear safety goggles.
Protective gloves.
Use local exhaust or breathing protection.
no data available
Information on basic physicochemical properties
- Physical stateneat
- ColourWhite crystals or platelets
- Odour
no data available
- Melting point/freezing point
53.5 °C. Atm. press.:Atmospheric pressure was not reported.
- Boiling point or initial boiling point and boiling range
218 °C.
- Flammability
Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
- Lower and upper explosion limit/flammability limit2.5-6.6%(V)
- Flash point
113 °C.
- Auto-ignition temperature
> 500 °C.
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
dynamic viscosity (in mPa s) = 1.68. Temperature:50.0°C.;dynamic viscosity (in mPa s) = 0.91. Temperature:100.0°C.
- Solubility0.02g/l
- Partition coefficient n-octanol/water
log Pow = 4.139. Temperature:25 °C.
- Vapour pressure0.07 mm Hg ( 25 °C)
- Density and/or relative density
1.45 g/cm3. Temperature:25 °C.
- Relative vapour density
6.25 (vs air)
- Particle characteristics
no data available
Reactivity
Decomposes on burning. This produces toxic and corrosive fumes including hydrogen chloride. Reacts with strong oxidants.
Chemical stability
no data available
Possibility of hazardous reactions
Slight when exposed to heat, flame, or oxidizers1,2,3-TRICHLOROBENZENE can react with oxidizing agents. (NTP, 1992). May emit toxic hydrogen chloride and phosgene gases in fire.
Conditions to avoid
no data available
Incompatible materials
On contact with acids or acid fumes they evolve highly toxic /hydrogen chloride/ fumes. chlorides
Hazardous decomposition products
When heated to decomp, it emits toxic fumes of /hydrogen chloride/. 2,3,6-trichlorobenzoic acid
Acute toxicity
- Oral: LD50 - rat (male/female) - > 5 000 mg/kg bw. Remarks:95% CL: Not applicable.
- Inhalation: no data available
- Dermal: LD50 DDY Mouse male percutaneous 300 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes and respiratory tract.
STOT-repeated exposure
no data available
Aspiration hazard
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.
Toxicity
- Toxicity to fish: LC100 - Danio rerio (previous name: Brachydanio rerio) - 30 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 0.46 mg/L - 48 h.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - 0.9 mg/L - 96 h.
- Toxicity to microorganisms: IC50 - Nitrosomonas sp. - 96 mg/L - 24 h.
Persistence and degradability
AEROBIC: Sediment from freshwater streams in the Netherlands degraded trichlorobenzenes, with reported biodegradation half-lives of 50 to 323 days(1). Trichlorobenzene was biodegraded by an acclimated anaerobic sediment slurry obtained from the Tsurumi River, Japan(2). First-order biodegradation rate constants in the range of 0.030-0.017/days were reported for trichlorobenzene, corresponding to half-lives of about 23-41 days(2). The half-life of trichlorobenzene in sewage sludge amended soil was in the range of 23-35 days(3). Utilizing the Japanese MITI test(4), 0% of the theoretical BOD was reached over a 2 week incubation period in sludge, indicating that biodegradation of trichlorobenzene may not be an important environmental fate process(SRC).
Bioaccumulative potential
Sediments and animals collected from near the discharge zone of the Los Angeles County wastewater treatment plant were analyzed for 27 selected organic compounds /including trichlorobenzene/ that had been identified in the effluent. The sediment and tissue concn of these organic compounds were positively correlated with each other and with the n-octanol/water partition coefficient, but these were negatively correlated with the effluent concn.
Mobility in soil
Log Koc values of 3.6-3.9 were measured for trichlorobenzene in sediment obtained from Ise Bay, Japan(1) and log Koc values of 4.5-5.0 were measured from sediment of Lake Ketelmeer, Netherlands(2). According to a recommended classification scheme(3), these Koc values suggest that trichlorobenzene has low mobility in soil(SRC).
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: UN2811 (For reference only, please check.)
IMDG: UN2811 (For reference only, please check.)
IATA: UN2811 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.)
IMDG: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.)
IATA: TOXIC SOLID, ORGANIC, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
UN number 2321 refers to liquid trichlorobenzenes.Liquid trichlorobenzenes are marine pollutants.See ICSCs 1049 and 344.
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.