Chrysene

Germ cell mutagenicity, Category 2

Carcinogenicity, Category 1B

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

H225 Highly Flammable liquid and vapour

H319 Causes serious eye irritation

H336 May cause drowsiness or dizziness

H341 Suspected of causing genetic defects

H350 May cause cancer

H351 Suspected of causing cancer

H410 Very toxic to aquatic life with long lasting effects

H412 Harmful to aquatic life with long lasting effects

P201 Obtain special instructions before use.

P202 Do not handle until all safety precautions have been read and understood.

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P273 Avoid release to the environment.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P281 Use personal protective equipment as required.

P391 Collect spillage. Hazardous to the aquatic environment

P308+P313 IF exposed or concerned: Get medical advice/attention.

P405 Store locked up.

P501 Dispose of contents/container to..…

P203 Obtain, read and follow all safety instructions before use.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P273 Avoid release to the environment.

P318 IF exposed or concerned, get medical advice.

P391 Collect spillage.

P405 Store locked up.

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

no data available

Fresh air, rest.

Remove contaminated clothes. Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth.

ACUTE/CHRONIC HAZARDS: Toxic. (NTP, 1992)

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Naphthalene and Related Compounds

Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot. For UN3508, be aware of possible short circuiting as this product is transported in a charged state. (ERG, 2016)

Use water spray, dry powder, foam, carbon dioxide.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up: Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.

NO open flames. Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Separated from strong oxidants. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.Keep container tightly closed in a dry and well-ventilated place.

TLV: A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued.MAK: skin absorption (H); carcinogen category: 2

no data available

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Wear safety goggles.

Protective gloves. Protective clothing.

Use local exhaust or breathing protection.

no data available

NIOSH considers coal tar pitch volatiles to be potential occupational carcinogens. Coal tar pitch volatiles

Decomposes on burning. This produces toxic fumes. Reacts violently with strong oxidants.

Stable under recommended storage conditions.

Dust explosion possible if in powder or granular form, mixed with air.Vigorous reactions, sometimes amounting to explosions, can result from the contact between aromatic hydrocarbons, such as CHRYSENE, and strong oxidizing agents. They can react exothermically with bases and with diazo compounds. Substitution at the benzene nucleus occurs by halogenation (acid catalyst), nitration, sulfonation, and the Friedel-Crafts reaction.

no data available

Incompatible materials: Strong oxidizing agents.

Hazardous decomposition products formed under fire conditions - Carbon oxides.

no data available

no data available

no data available

no data available

CLASSIFICATION: B2; probable human carcinogen. BASIS FOR CLASSIFICATION: No human data and sufficient data from animal bioasays. Chrysene produced carcinomas and malignant lymphoma in mice after intraperitoneal injection and skin carcinomas in mice following dermal exposure. Chrysene produced chromosomal abnormalities in hamsters and mouse germ cells after gavage exposure, positive responses in bacterial gene mutation assays and transformed mammalian cells exposed in culture. HUMAN CARCINOGENICITY DATA: None. ANIMAL CARCINOGENICITY DATA: Sufficient.

no data available

no data available

This substance is possibly carcinogenic to humans.

A harmful concentration of airborne particles can be reached quickly when dispersed.

AEROBIC: Biodegradation half-lives of 371 and 387 days were observed for chrysene in Kidman and McLaurin sandy loam soils, respectively(1). No significant degradation of chrysene was observed in soil obtained from a former tar-oil refinery following 8 weeks of incubation in a percolator(2). However, when sand was contaminated with soil extracts containing polycyclic aromatic hydrocarbons, including chrysene, and inoculated with a polycyclic aromatic hydrocarbon degrading mixed culture, the chrysene concentration was reduced from approx. 50 mg/kg soil to approx. 19 mg/kg soil(2). The inhibition of chrysene biodegradation was attributed to binding of chrysene with the soil(2). In a 240 day soil microcosm study, half-lives of 980, 1000, and 730 days at 10, 20, and 30 deg C, respectively, were estimated for chrysene(3). In bench-scale biotreatability studies using a solid-phase bioremediation process (landfarming chambers containing sediment and soil collected from the American Creosote Works Superfund site, Pensacola, FL), the chrysene concentration was reduced from 114.0 to 53.4 mg/landfarming chamber in unamended surface soil; 114.0 to 46.2 mg/landfarming chamber in nutrient-amended surface soil; 1443.6 to 1146.6 mg/landfarming chamber in unamended sediment; and 1443.6 to 992.4 mg/landfarming chamber in nutrient-amended sediment following 12 weeks incubation(4). After 16 months incubation in biologically active soils containing 1-phenyldecane as a primary substrate, 84% of chrysene was recovered; 95% of chrysene was recovered from a poisoned control after 16 months incubation(5). Half-lives for chrysene ranged from 1000 days, using a synthetic mixture of polycyclic aromatic hydrocarbons applied and incubated together in Kidman sandy loam soil, to 77 days in a mixture of oil refinery wastes applied to Kidman sandy loam soil(6). A half-life of 371 days was observed for chrysene when applied and incubated as a single constituent in Kidman sandy loam soil(6).

Some marine organisms have no detectable aryl hydrocarbon hydroxylase enzyme systems, namely: phytoplankton, certain zooplankton, mussels (Mytilus edulis), scallops (Placopecten sp), and snails (Litternia littorea). ... Those organisms which lack a metabolic detoxification enzyme system, tend to accumulate polycyclic aromatic hydrocarbons. Polycyclic aromatic hydrocarbons

The log Koc value for chrysene in 100 soil samples was 6.11-7.34(1). The log Koc for chrysene was reported as 5.40(2). The log Koc value of chrysene measured in sediment from San Francisco Bay was 5.98(3). The log Koc of chrysene in sediment collected from Utica Harbor, NY and the Rouge River, MI was 4.81-6.75(4). The log Koc values for chrysene in 52 sediment samples was 5.12-7.79(5). According to a classification scheme(6), the reported log Koc values suggest that chrysene is expected to be immobile in soil. Sorption removal accounted for >6.2% and >8.5% of the chrysene present in the influent of a high-loaded laboratory scale activated sludge reactor and a biological aerated filter reactor, respectively(7).

no data available

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

ADR/RID: UN3077 (For reference only, please check.)

IMDG: UN3077 (For reference only, please check.)

IATA: UN3077 (For reference only, please check.)

ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)

IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)

IATA: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)

ADR/RID: 9 (For reference only, please check.)

IMDG: 9 (For reference only, please check.)

IATA: 9 (For reference only, please check.)

ADR/RID: III (For reference only, please check.)

IMDG: III (For reference only, please check.)

IATA: III (For reference only, please check.)

ADR/RID: Yes

IMDG: Yes

IATA: Yes

no data available

no data available

Depending on the degree of exposure, periodic medical examination is suggested.Do NOT take working clothes home.This substance does not usually occur as a pure substance but as a component of polyaromatic hydrocarbon (PAH) mixtures.Human population studies have associated PAH's exposure with cancer and cardiovascular diseases.TLV Note: Exposure by all routes should be carefully controlled to levels as low as possible.