Clopyralid
Product identifier
- Product name: Clopyralid
- CBnumber: CB7186620
- CAS: 1702-17-6
- EINECS Number: 216-935-4
- Synonyms: clopyralid,3,6-dichloropicolinic acid
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Serious eye damage, Category 1
Label elements
Pictogram(s)
- Signal wordDanger
H318 Causes serious eye damage
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
none
none
Other hazards
no data available
Substance
- Product name: Clopyralid
- Synonyms: clopyralid,3,6-dichloropicolinic acid
- CAS: 1702-17-6
- EC number: 216-935-4
- MF: C6H3Cl2NO2
- MW: 192
Description of first aid measures
If inhaledFresh air, rest.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth.
Most important symptoms and effects, both acute and delayed
no data available
Indication of any immediate medical attention and special treatment needed
No specific antidote known. Symptomatic treatment.
Extinguishing media
Use water spray, powder.
Specific Hazards Arising from the Chemical
Combustible.
Advice for firefighters
Use water spray, powder.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Do not contaminate water when cleaning equipment or disposing of equipment washwaters. Lontrel Turf and Ornamental
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Do NOT store or transport in containers made from aluminium.Do not store or transport in containers made from aluminium.
Control parameters
Occupational Exposure limit valuesno data available
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear safety goggles.
Protective gloves.
Use local exhaust or breathing protection.
no data available
Information on basic physicochemical properties
- Physical stateneat
- Colour
White crystalline solid
- Odour
Odorless
- Melting point/freezing point
130°C(lit.)
- Boiling point or initial boiling point and boiling range
162°C/15mmHg(lit.)
- Flammability
Combustible.
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
56°C(lit.)
- Auto-ignition temperature
no data available
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
no data available
- Solubility
In water, 7.85X10+3 mg/L (distilled water); 188 g/L at pH 5, 143 g/L ay pH 7; 157 g/L at pH 9, all at 20 deg C
- Partition coefficient n-octanol/water
log Kow = 1.06
- Vapour pressure
0.000599mmHg at 25°C
- Density and/or relative density
1.612 g/cm3
- Relative vapour density
no data available
- Particle characteristics
no data available
Reactivity
Decomposes on burning. This produces toxic and corrosive fumes of nitrogen oxides and chlorine (see ICSC 0126). The solution is corrosive to aluminum, iron and tin.
Chemical stability
Store above 28 deg F or warm to 40 deg F and agitate before use.
Possibility of hazardous reactions
Decomposes on burning. This produces toxic and corrosive fumes of nitrogen oxides and chlorine (see ICSC 0126). The solution is corrosive to aluminum, iron and tin.
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
When heated to decomposition it emit toxic fumes of /hydrogen chloride and nitrogen oxides/.
Acute toxicity
- Oral: LD50 Rat male oral 4300 mg/kg
- Inhalation: no data available
- Dermal: LD50 Rabbit percutaneous > 2000 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Not Likely to be Carcinogenic to Humans
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes, skin and respiratory tract.
STOT-repeated exposure
no data available
Aspiration hazard
Evaporation at 20°C is negligible; a nuisance-causing concentration of airborne particles can, however, be reached quickly.
Toxicity
- Toxicity to fish: LC50; Species: Oncorhynchus mykiss (Rainbow trout); Concentration: 103.5 mg/L for 96 hr /Conditions of bioassay not specified
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: While some investigators found clopyralid to be biodegradable in field soils(1-2), others found that the herbicide was relatively persistent in field soil(3). Thus the biodegradation of clopyralid appears to be soil dependent and the rate of biodegradation in soil may be enhanced both by higher temperature and higher number of organisms that are capable of degrading the herbicide(4). The half-lives of clopyralid in a clay, clay loam and sandy loam soil at 20 deg C and 85% field moisture capacity were estimated to be 38 days, 13 days and 36 days, respectively(4).
Bioaccumulative potential
A BCF of 19 was reported in fish for clopyralid in a flowing water test(1). According to a classification scheme(2), this BCF suggests the bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
Koc values of 2(1), 4.6(2) and 0.4 to 12.9(3) have been reported. According to a classification scheme(4), these Koc values suggest that clopyralid is expected to have very high mobility in soil. However, many leachate studies have reported little or no clopyralid detected in the leachate(2,5-6). The pKa of clopyralid is 2.32(7), indicating that this compound will exist almost entirely in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(8).
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.