Fenitrothion

Acute toxicity - Category 4, Oral

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

H225 Highly Flammable liquid and vapour

H301 Toxic if swalloed

H304 May be fatal if swallowed and enters airways

H312 Harmful in contact with skin

H315 Causes skin irritation

H330 Fatal if inhaled

H336 May cause drowsiness or dizziness

H410 Very toxic to aquatic life with long lasting effects

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P273 Avoid release to the environment.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P331 Do NOT induce vomiting.

P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P370+P378 In case of fire: Use … for extinction.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P501 Dispose of contents/container to..…

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P273 Avoid release to the environment.

P301+P317 IF SWALLOWED: Get medical help.

P330 Rinse mouth.

P391 Collect spillage.

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P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

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Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention .

This compound is an organophosphate insecticide. It is a highly toxic cholinesterase inhibitor, that acts on the nervous system. Does not cause delayed neurotoxicity and contact produces little irritation. (EPA, 1998)

Basic Treatment: Establish a patent airway. Suction if necessary. Aggressive airway control may be needed. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . Monitor for shock and treat if necessary. Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal . Organophosphates and related compounds

Non-Specific -- Organophosphate Pesticide n.o.s.) Move containers from fire area if you can do so without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material. Wear positive pressure breathing apparatus and special protective clothing. This compound is an organophosphate insecticide. Small fires: dry chemical, carbon dioxide, water spray, or foam. Large fires: water spray, fog or foam. (EPA, 1998)

When heated to decomposition, it emits very toxic fumes of oxides of nitrogen, phosphorus and sulfur. Decomposition at 212-284F produces a mixture of organophosphorus polymers. Unstable in alkaline media. Stable for 2 years if stored at 68-77F. Do not store above 104F. (EPA, 1998)

Use water spray, powder, foam, carbon dioxide.

Personal protection: chemical protection suit including self-contained breathing apparatus. Absorb remaining liquid in sand or inert absorbent. Collect leaking liquid in covered containers. Then store and dispose of according to local regulations. Do NOT wash away into sewer. Do NOT let this chemical enter the environment.

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer. Personal protection: chemical protection suit including self-contained breathing apparatus.

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Keep in a well-ventilated room./Storage temperature should be less than 40 deg C on account of the tendency/ to isomerize.

no data available

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Wear face shield or eye protection in combination with breathing protection.

Protective gloves. Protective clothing.

Use ventilation, local exhaust or breathing protection.

no data available

Decomposes on heating and on burning. This produces toxic fumes including nitrogen oxides, phosphorus oxides and sulfur oxides.

It is hydrolyzed by alkali, in 10 m sodium hydroxide 50% loss occurs in 4.5 hr @ 30 deg c

Organophosphates, such as FENITROTHION, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

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Cancer Classification: Group E Evidence of Non-carcinogenicity for Humans

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The substance is irritating to the eyes and skin. The substance may cause effects on the nervous system. This may result in convulsions, respiratory failure and death. Cholinesterase inhibition. The effects may be delayed. Medical observation is indicated.

Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C.

The loss of fenitrothion was faster in non-sterile soil than sterile soil indicating degradation in soil was a combination of abiotic and microbial reactions(1). The rate of fenitrothion degradation in soil depended on pH, soil type, organic amendment, soil moisture content and pesticide concentration(1). The half-life was 1608 days in a non-sterile sandy loam soil containing 1,000 ppm fenitrothion at a soil pH 7.2 and moisture content of 50%(1). On the other hand, the biodegradation half-life was 13 days in a non-sterile clay loam soil containing 100 ppm fenitrothion at a soil pH 10 and moisture content of 50%(1).

There were no consistent differences in concn of fenitrothion in streamwater with depth, or between midstream and slow water at the stream edge. This was true of aq and oil-based formulations. A large portion of the fenitrothion was taken up by suspended material; in sediment, it was taken up mainly by the organic fraction. Concn of fenitrothion were above pre-spray values in most plants and insects sampled, and in some, above peak concn found in the water. Highest and most persistent residues were found in a livewort. Highest residues in an animal were found in black fly larvae, perhaps explained by their filter-feeding on suspended matter with high fenitrothion concn. Peak concn in plants and animals usually occured at 6 or 24 hr postspray sampling times, and in all cases decr thereafter. Aminofenitrothion and fenitrooxon in sediments and 3-methyl-4-nitrophenol in plants and insects were seldom and inconsistently detected.

Measured fenitrothion Koc values of 593 and 254 in Tsukuba and Kanuma soils(1) and 1531, 1201, 833, and 1061 in 4 rice soils(2) have been determined. According to a classification scheme(3), these Koc value suggests that fenitrothion is expected to have low to moderate mobility in soil. A study conducted on organic and silty clay loam soil, from the Boreal Forest in Ontario, Canada, indicate a maximum adsorption rate of 92 ug/g and 81 ug/g, respectively, in 30 hrs when fenitrothion-acetone is added to the soils(4). In the same experiment, studies with a buffer solution showed 38 and 48% desorption rate after 50 hrs extraction time(4).

no data available

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

ADR/RID: UN3018 (For reference only, please check.)

IMDG: UN3018 (For reference only, please check.)

IATA: UN3018 (For reference only, please check.)

ADR/RID: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)

IMDG: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)

IATA: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)

ADR/RID: 6.1 (For reference only, please check.)

IMDG: 6.1 (For reference only, please check.)

IATA: 6.1 (For reference only, please check.)

ADR/RID: I (For reference only, please check.)

IMDG: I (For reference only, please check.)

IATA: I (For reference only, please check.)

ADR/RID: Yes

IMDG: Yes

IATA: Yes

no data available

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Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.Carrier solvents used in commercial formulations may change physical and toxicological properties.Do NOT take working clothes home.