Polychlorinated Biphenyls (PCBs)
Product identifier
- Product name: Polychlorinated Biphenyls (PCBs)
- CBnumber: CB7160460
- CAS: 1336-36-3
- EINECS Number: 215-648-1
- Synonyms: Polychlorinated biphenyls,Pyranol
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Specific target organ toxicity – repeated exposure, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
Label elements
Pictogram(s)
-
Signal word
Warning
H373 May cause damage to organs through prolonged or repeated exposure
H410 Very toxic to aquatic life with long lasting effects
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P319 Get medical help if you feel unwell.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: Polychlorinated Biphenyls (PCBs)
- Synonyms: Polychlorinated biphenyls,Pyranol
- CAS: 1336-36-3
- EC number: 215-648-1
- MF: N/A
- MW: 0
Description of first aid measures
If inhaledMove the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms and effects, both acute and delayed
no data available
Indication of any immediate medical attention and special treatment needed
If PCB-containing substances have been ingested recently, gastric decontamination may be reasonable. Activated charcoal has not been proven beneficial, but is not contraindicated.
Extinguishing media
Use dry chemical, carbon dioxide, or alcohol foam extinguishers. Vapors are heavier than air and will collect in low areas. Vapors in confined areas may explode when exposed to fire. Containers may explode in fire. Storage containers and parts of containers may rocket great distances, in many directions. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Notify local health and fire officials and pollution control agencies. From a secure, explosion-proof location, use water spray to cool exposed containers. If cooling streams are ineffective (venting sound increases in volume and pitch, tank discolors, or shows any signs of deforming), withdraw immediately to a secure position ... The only respirators recommended for fire fighting are self-contained breathing apparatuses that have full facepieces and are operated in a pressure-demand or other positive pressure mode.
Specific Hazards Arising from the Chemical
no data available
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Dry sand or earth should be spread on the leak, or spill area. ...
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
PCB material should be stored in closed containers, in ventilated areas ... PCB's should be handled in isolated areas of the plant, where efficient ventilation systems remove airborne PCB's. ...
Control parameters
Occupational Exposure limit values| Component | 1,1'-Biphenyl, chloro derivs. | |||
|---|---|---|---|---|
| CAS No. | 1336-36-3 | |||
| Limit value - Eight hours | Limit value - Short term | |||
| ppm | mg/m3 | ppm | mg/m3 | |
| Canada - Ontario | ? | 0,05 (1) | ? | ? |
| Denmark | ? | 0,01 | ? | 0,02 |
| Finland | ? | 0,003 (1) | ? | ? |
| Germany (DFG) | ? | 0,003 (1)(2)(3)(5) | ? | 0,024 (1)(2)(3)(4)(5) |
| Hungary | ? | POP | ? | ? |
| Ireland | ? | 0,1 | ? | ? |
| Japan | ? | 0,01 | ? | ? |
| Japan - JSOH | ? | 0,01 | ? | ? |
| Latvia | ? | 1 | ? | ? |
| New Zealand | ? | 0,1 | ? | ? |
| Poland | ? | 1 | ? | ? |
| Sweden | ? | 0,01 | ? | 0,03 (1) |
| Switzerland | 0,05 | 0,5 | 0,4 | 4 |
| United Kingdom | ? | 0,1 | ? | ? |
| Remarks | ||||
| Canada - Ontario | (1) as sum of components assayed by chromatographic procedure with reference of the bulk sample | |||
| Finland | (1) Total PCB = 5*([PCB 28] + [PCB 52] + [PCB 101 ] + [PCB 138] + [PCB 153] + [PCB 180]) | |||
| Germany (AGS) | (1) 42% Chlorine (CAS-No. 53469-21-9) (2) 54% Chlorine (CAS-No. 11097-69-1) | |||
| Germany (DFG) | (1) Only for chlorinated biphenyls with Cl | |||
| Hungary | POP Persistent Organic Pollutant | |||
| Sweden | (1) Short-term value, 15 minutes average value | |||
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
Information on basic physicochemical properties
- Physical state
no data available
- Colour
Vary from mobile oily liquids to white crystalline solids and hard noncrystalline resins.
- Odour
Practically odorless; mild aromatic odor
- Melting point/freezing point
no data available
- Boiling point or initial boiling point and boiling range
340～375
- Flammability
no data available
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
195(O.C)
- Auto-ignition temperature
no data available
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
no data available
- Solubility
Solubility in water is extremely low; soluble in oils and organic solvents.
- Partition coefficient n-octanol/water
... literature Kow values will vary. These increase with increasing chlorination. log Kow values at 25 deg C: 3.76 (biphenyl); 5.7 (Cl4-PCB's); 6.0 (Cl5-PCB's); 7.0 (Cl6-PCB's); 8.26 (Cl10-PCB's).
- Vapour pressure
2.04E-07mmHg at 25°C
- Density and/or relative density
1.44(30°C)
- Relative vapour density
no data available
- Particle characteristics
no data available
Reactivity
NIOSH considers chlorodiphenyl containing 54% chlorine to be a potential occupational carcinogen. Aroclor 1254
NIOSH considers chlorodiphenyl containing 54% chlorine to be a potential occupational carcinogen. Aroclor 1254
Chemical stability
PCB's are chemically very inert and are stable to conditions of hydrolysis and oxidation in industrial use. Photochemical degradation may be one route of their breakdown in the environment. ...
Possibility of hazardous reactions
Flame resistant.
Conditions to avoid
no data available
Incompatible materials
Liquid chlorine reacts exothermically with polychlorinated biphenyl heat transfer liquid. Polychlorinated biphenyl
Hazardous decomposition products
When heated to decomposition it emits toxic fumes of Chloride.
Acute toxicity
- Oral: LD50 Mouse (C57B1/6J) male oral 19 mg/kg/28 day
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
EPA: Possibly carcinogenic to humans, IARC: Probably carcinogenic to humans, NTP: Known to be a human carcinogen
Reproductive toxicity
An epidemiological study of women occupationally exposed to high levels of PCBs suggested a relationship between PCB exposure and reduced birth weight and shortened gestational age of their babies; however, limitations of the study limit the strength of the conclusion. Two series of human studies that investigated exposure to PCBs through the consumption of contaminated fish suggest that exposure to PCBs may cause developmental effects in humans. Both studies reported an association between consumption of fish with high PCB levels by pregnant women and an increased incidence of neurodevelopmental effects, such as motor deficits at birth, impaired psychomotor index, impaired visual recognition, and deficits in short-term memory in infants. Human studies are not conclusive on the reproductive effects of PCBs. One study of men who were occupationally exposed to PCBs showed no fertility abnormalities, while another study of men with low sperm counts found elevated levels of PCBs in the blood and an association between certain PCB compounds in semen and decreased sperm motility. Animal studies have reported developmental effects, such as learning deficits, impaired immune functions, focal liver necrosis, and cellular alterations of the thyroid, in the offspring of animals exposed orally to PCBs. Reproductive effects, such as decreased fertility, decreased conception, and prolonged menstruation have also been noted in animal studies of dietary PCB exposures.
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (green algae); Conditions: freshwater, static, 22 deg C; Concentration: 182 nmol/L for 48 hr; Effect: decreased population biomass />98% pure
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: The microbial mineralization of three chlorophenols and a PCB mixture was studied using natural bacterial assemblages in laboratory model systems. The systems consisted of water and surface sediment from two lake types: one with a high content of humic substances and the other with a low content. Final PCB concentration in the model systems was 38 ug/L. Aerobic mineralization of the (14)C-ring-labelled compounds was determined as production of (14)CO2 in the systems over the course of 60 days. Mineralization of PCBs in the systems was low compared to the aromatics. The breakdown of PCB was 0.047 nM in the humic cultures and 0.052 nM in cultures from the clear water lake. The avg mineralization rates of PCBs over the 60 day test period for the clear-water and humic cultures were 1.1 and 1.2 pM/day. More than 90% of the PCBs adsorbed to the sediment, while <1% was found in the water phase.
Bioaccumulative potential
Polychlorinated biphenyls (PCBs) are highly lipophilic and bioconcentrate in tissue from concentrations in water ...
Mobility in soil
PCB mobility in aqueous soil-sediment systems has reported experimental Koc values ranging from 510 to 13,300,000 for a variety of Aroclors and PCB congeners; reported Koc values were mostly above 5000(1). Reviews of the PCB mobility literature have found that adsorption of PCBs to soil and sediment generally increases with an increase in the degree of chlorination(2,3). Organic solvents, found at hazardous waste sites, will also increase the solubility and mobility of PCBs(3). Using soil TLC, column leaching and five different soils, PCBs were found to be generally immobile when leached with water or aqueous landfill leachate, but highly mobile when leached with organic solvents(4). PCB fluids can penetrate and travel through the cracks and other connected void spaces found in soil formations(5). In the presence of organic material dissolved from soil, the water solubility of PCBs increases which may augment its leachability. Environmental releases of PCBs often accompany releases of carrier materials from utility equipment. The PCBs that are present in the mineral oil-PCB mixture become even less water soluble than before. This is due to the PCB partitioning into the mineral oil and the reduced interaction of the PCBs with precipitation or groundwater caused by the hydrophobic nature of the oil matrix. The volatility of PCBs also affects their migration through the soil profile. Researchers have carried out simulations that indicate that PCBs can volatilize beneath the soil surface and potentially migrate through several meters of soil cover(5).
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.