BUCILLAMINE
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- Product name: BUCILLAMINE
- CAS: 65002-17-7
- MF: C7H13NO3S2
- MW: 223.31
- EINECS:
- MDL Number:MFCD00867570
- Synonyms:sa96 ;thiobutarit ;BUCILLAMINE;(R)-3-Mercapto-2-(2-Mercapto-2-MethylpropanaMido)propanoic acid;de-019 ;L-Cysteine, N-(2-mercapto-2-methyl-1-oxopropyl)-;N-(2-Mercaptoisobutyryl)cysteine;Tiobutarit
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Properties
Melting point :119-123°C
alpha :D25 +32.3° (c = 1.0 in ethanol)
Boiling point :438.0±45.0 °C(Predicted)
Density :1.3934 (rough estimate)
refractive index :1.6370 (estimate)
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :DMSO (Very Slightly), Ethanol (Slightly), Methanol (Slightly), Water (Slightly)
pka :3.01±0.10(Predicted)
form :Solid
color :White to Pale Yellow
Stability :Air Sensitive, Hygroscopic, Unstable in Solution
CAS DataBase Reference :65002-17-7(CAS DataBase Reference)
alpha :D25 +32.3° (c = 1.0 in ethanol)
Boiling point :438.0±45.0 °C(Predicted)
Density :1.3934 (rough estimate)
refractive index :1.6370 (estimate)
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :DMSO (Very Slightly), Ethanol (Slightly), Methanol (Slightly), Water (Slightly)
pka :3.01±0.10(Predicted)
form :Solid
color :White to Pale Yellow
Stability :Air Sensitive, Hygroscopic, Unstable in Solution
CAS DataBase Reference :65002-17-7(CAS DataBase Reference)
Safety Information
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Description
Bucillamine is an orally active immunomodulator useful in the treatment of rheumatoid arthritis. Its potencies in inhibiting collagenase activity and inactivating rheumatoid factor far exceed those of penicillamine. In man, bucillamine reportedly brings about significant improvements over placebo in erythrocyte sedimentation, grip power, joint swelling and duration of morning stiffness.Related product price
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