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Boceprevir

Boceprevir Structure
  • ₹9544.02 - ₹33656.22
  • Product name: Boceprevir
  • CAS: 394730-60-0
  • MF: C27H45N5O5
  • MW: 519.68
  • EINECS:800-043-2
  • MDL Number:MFCD22208555
  • Synonyms:Boceprevir (1R,2S,5S)-N-(4-Amino-1-cyclobutyl-3,4-dioxobutan-2-yl)-3-[(2S)-2-(tert-butylcarbamoylamino)-3,3-dimethylbutanoyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide;Boceprevir, >=98%;Boceprevir;(1R,2S,5S)-N-(4-Amino-1-cyclobutyl-3,4-dioxobutan-2-yl)-3-[(2S)-2-(tert-butylcarbamoylamino)-3,3-dimethylbutanoyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide;EBP 520;Sch 503034;3-Azabicyclo[3.1.0]hexane-2-carboxaMide, N-[3-aMino-1-(cyclobutylMethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[(1,1-diMethylethyl)aMino]carbonyl]aMino]-3,3-diMethyl-1-oxobutyl]-6,6-diMethyl-, (1R,2S,5S)-;Bocepravir
Price2 Properties Safety Information Description
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML3137
  • Product descriptionBoceprevir ≥98% (HPLC)
  • Packaging10MG
  • Price₹9544.02
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML3137
  • Product descriptionBoceprevir ≥98% (HPLC)
  • Packaging50MG
  • Price₹33656.22
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML3137 Boceprevir ≥98% (HPLC) 10MG ₹9544.02 2022-06-14 Buy
Sigma-Aldrich(India) SML3137 Boceprevir ≥98% (HPLC) 50MG ₹33656.22 2022-06-14 Buy

Properties

Melting point :>107°C (dec.)
Density :1.162
storage temp. :-20°C
solubility :Soluble in DMSO (up to 15 mg/ml with warming)
form :solid
pka :12.82±0.40(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Boceprevir is a protease inhibitor that covalently, yet reversibly, binds (Ki = 14 nM) to the catalytic site (Ser139) of hepatitis C virus (HCV) nonstructural protein 3/4A (NS3/4A), a serine protease that is essential for viral replication. It was shown to inhibit the NS3/4A protease in an in vitro HCV replicon system with an EC50 value of 200 nM. Boceprevir can inhibit the activity of recombinant HCV genotype 1a and 1b NS3/4A protease enzymes in vitro with Ki values of 14 nM for each subtype. It has been evaluated in phase III clinical studies in combination with the current standard of care for treatment of HCV.

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Suppliers and manufacturers

career henan chemical co
Boceprevir
₹10.00 /1KG
Boceprevir CAS:394730-60-0
BDR Pharmaceuticals International Pvt Ltd Pharma Affiliates CLEARSYNTH LABS LTD. A.J Chemicals Triveni chemicals Pharmaffiliates Analytics and Synthetics P. Ltd Taj Mahal Vision Chemicals Private Limited
Alpha Biopharmaceuticals Co., Ltd
Henan Tianfu Chemical Co.,Ltd.