(-)-COTININE
- ₹2673.3 - ₹45529.95
- Product name: (-)-COTININE
- CAS: 486-56-6
- MF: C10H12N2O
- MW: 176.22
- EINECS:207-634-9
- MDL Number:MFCD00077696
- Synonyms:L-COTININE;(-)-COTININE;(S)-(-)-1-METHYL-5-(3-PYRIDIYL)-2-PYRROLIDINONE;[S]-1-METHYL-5-[3-PYRIDYL]-2-PYRROLIDINONE;S(-)-1-METHYL-5-(3-PYRIDYL)-2-PYRROLIDONE;(s)-1-methyl-5-(3-pyridinyl)-2-pyrrolidinone ;(s)-2-pyrrolidinon ;1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone
5 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 25MG
- 50MG
- 250MG
- 1ML
- 1G
- ManufacturerSigma-Aldrich(India)
- Product numberPHR2533
- Product descriptionNicotine Related Compound C Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging50MG
- Price₹45529.95
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC5923
- Product description(−)-Cotinine ≥98%
- Packaging1G
- Price₹26034.13
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC5923
- Product description(−)-Cotinine ≥98%
- Packaging250MG
- Price₹13206.5
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number74003
- Product description(−)-Cotinine analytical standard
- Packaging25MG
- Price₹6679.03
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC-016
- Product description(−)-Cotinine solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging1ML
- Price₹2673.3
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | PHR2533 | Nicotine Related Compound C Pharmaceutical Secondary Standard; Certified Reference Material | 50MG | ₹45529.95 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C5923 | (−)-Cotinine ≥98% | 1G | ₹26034.13 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C5923 | (−)-Cotinine ≥98% | 250MG | ₹13206.5 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 74003 | (−)-Cotinine analytical standard | 25MG | ₹6679.03 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C-016 | (−)-Cotinine solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | 1ML | ₹2673.3 | 2022-06-14 | Buy |
Properties
Melting point :40-42 °C(lit.)
Boiling point :250 °C150 mm Hg(lit.)
alpha :[α]D20 -18~-22° (c=1, C2H5OH)
Density :1.1102 (rough estimate)
refractive index :1.7110 (estimate)
Flash point :>230 °F
storage temp. :Sealed in dry,2-8°C
solubility :Chloroform (Sparingly), DMSO (Slightly), Methanol (Sparingly)
form :Solid
pka :4.72±0.12(Predicted)
color :Colourless to Very Dark Orange Oil
optical activity :[α]/D -21±2°, c = 1 in ethanol
Water Solubility :Not miscible or difficult to mix in water. Soluble in dimethyl sulfoxide (100 mM), ethanol (50 mg/ml, yielding a clear, faint yellow to yellow solution), methanol and chloroform.
Merck :14,2553
BRN :83099
Stability :Stable. Incompatible with strong oxidizing agents. May be heat sensitive - store cold.
EPA Substance Registry System :Cotinine (486-56-6)
Boiling point :250 °C150 mm Hg(lit.)
alpha :[α]D20 -18~-22° (c=1, C2H5OH)
Density :1.1102 (rough estimate)
refractive index :1.7110 (estimate)
Flash point :>230 °F
storage temp. :Sealed in dry,2-8°C
solubility :Chloroform (Sparingly), DMSO (Slightly), Methanol (Sparingly)
form :Solid
pka :4.72±0.12(Predicted)
color :Colourless to Very Dark Orange Oil
optical activity :[α]/D -21±2°, c = 1 in ethanol
Water Solubility :Not miscible or difficult to mix in water. Soluble in dimethyl sulfoxide (100 mM), ethanol (50 mg/ml, yielding a clear, faint yellow to yellow solution), methanol and chloroform.
Merck :14,2553
BRN :83099
Stability :Stable. Incompatible with strong oxidizing agents. May be heat sensitive - store cold.
EPA Substance Registry System :Cotinine (486-56-6)
Safety Information
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Description
Cotinine is a minor alkaloid found in tobacco plants and is a major metabolite of nicotine. It has a long pharmacological half-life (15-19 hours) compared to that of nicotine (2-3 hours) and is often used as a biomarker to detect tobacco use. Cotinine binds nicotinic- and muscarinic-type acetylcholine receptors with minimal receptor desensitization and demonstrates antipsychotic drug-like properties in behavioral models, neuroprotective properties in neurodegenerative disease models, and enhances attention in a delayed matching-to-sample task.Related product price
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