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DY131

DY131 Structure
  • ₹8616.7 - ₹34726.6
  • Product name: DY131
  • CAS: 95167-41-2
  • MF: C18H21N3O2
  • MW: 311.38
  • EINECS:
  • MDL Number:MFCD00715585
  • Synonyms:GSK 9089;DY131(GSK 9089);4-Hydroxybenzoic acid 2-[[4-(diethylamino)phenyl]methylene]hydrazide;DY131;DY-131;DY 131;GSK4716;GW4716;GW574716;DY131
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberD3946
  • Product descriptionDY 131 ≥98% (HPLC)
  • Packaging5MG
  • Price₹8616.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD3946
  • Product descriptionDY 131 ≥98% (HPLC)
  • Packaging25MG
  • Price₹34726.6
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) D3946 DY 131 ≥98% (HPLC) 5MG ₹8616.7 2022-06-14 Buy
Sigma-Aldrich(India) D3946 DY 131 ≥98% (HPLC) 25MG ₹34726.6 2022-06-14 Buy

Properties

Melting point :234-236 °C
Density :1.11±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: ≥14 mg/mL
form :solid
pka :8.47±0.15(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The estrogen-related receptors (ERRs) are orphan nuclear receptors with homology to the ER family and are expressed in tissues with high metabolic demand. DY 131 is a selective agonist of the ERRβ/γ receptor (EC50 = 130 nM). It does not affect the ERRα receptor nor the ERs α and β at concentrations up to 30 μM. DY 131 has been used to potentiate ERRγ-induced growth inhibition in LNCaP and DU145 prostate cancer cell lines in order to demonstrate an antiproliferative/tumor-suppressing function for ERRγ in prostate cancer.

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