Boceprevir
- ₹9544.02 - ₹33656.22
- Product name: Boceprevir
- CAS: 394730-60-0
- MF: C27H45N5O5
- MW: 519.68
- EINECS:800-043-2
- MDL Number:MFCD22208555
- Synonyms:Boceprevir (1R,2S,5S)-N-(4-Amino-1-cyclobutyl-3,4-dioxobutan-2-yl)-3-[(2S)-2-(tert-butylcarbamoylamino)-3,3-dimethylbutanoyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide;Boceprevir, >=98%;Boceprevir;(1R,2S,5S)-N-(4-Amino-1-cyclobutyl-3,4-dioxobutan-2-yl)-3-[(2S)-2-(tert-butylcarbamoylamino)-3,3-dimethylbutanoyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide;EBP 520;Sch 503034;3-Azabicyclo[3.1.0]hexane-2-carboxaMide, N-[3-aMino-1-(cyclobutylMethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[(1,1-diMethylethyl)aMino]carbonyl]aMino]-3,3-diMethyl-1-oxobutyl]-6,6-diMethyl-, (1R,2S,5S)-;Bocepravir
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML3137
- Product descriptionBoceprevir ≥98% (HPLC)
- Packaging10MG
- Price₹9544.02
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML3137
- Product descriptionBoceprevir ≥98% (HPLC)
- Packaging50MG
- Price₹33656.22
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML3137 | Boceprevir ≥98% (HPLC) | 10MG | ₹9544.02 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML3137 | Boceprevir ≥98% (HPLC) | 50MG | ₹33656.22 | 2022-06-14 | Buy |
Properties
Melting point :>107°C (dec.)
Density :1.162
storage temp. :-20°C
solubility :Soluble in DMSO (up to 15 mg/ml with warming)
form :solid
pka :12.82±0.40(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Density :1.162
storage temp. :-20°C
solubility :Soluble in DMSO (up to 15 mg/ml with warming)
form :solid
pka :12.82±0.40(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Signal word: | Warning | ||||||||||||
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Description
Boceprevir is a protease inhibitor that covalently, yet reversibly, binds (Ki = 14 nM) to the catalytic site (Ser139) of hepatitis C virus (HCV) nonstructural protein 3/4A (NS3/4A), a serine protease that is essential for viral replication. It was shown to inhibit the NS3/4A protease in an in vitro HCV replicon system with an EC50 value of 200 nM. Boceprevir can inhibit the activity of recombinant HCV genotype 1a and 1b NS3/4A protease enzymes in vitro with Ki values of 14 nM for each subtype. It has been evaluated in phase III clinical studies in combination with the current standard of care for treatment of HCV.Related product price
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