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nimbolide

nimbolide Structure
  • ₹45811.4
  • Product name: nimbolide
  • CAS: 25990-37-8
  • MF: C27H30O7
  • MW: 466.52
  • EINECS:
  • MDL Number:MFCD31924824
  • Synonyms:nimbolide;(17R)-7α,15β:21,23-Diepoxy-6α-hydroxy-4,8-dimethyl-1-oxo-11-methoxycarbonyl-18,24-dinor-11,12-seco-5α-chola-2,13,20,22-tetrene-4α-carboxylic acid γ-lactone;NSC 309909;2H,5H-Cyclopenta[d']naphtho[1,8-bc:2,3-b']difuran-6-acetic acid, 8-(3-furanyl)-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2a,5a,6a,7-tetramethyl-2,5-dioxo-, methyl ester, (2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-;methyl [(2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-8-furan-3-yl-2a,5a,6a,7-tetramethyl-2,5-dioxo-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2H,5H-cyclopenta[d]naphtho[2,3-b:1,8-b''c'']difuran-6-yl]acetate;Nimbolide (25 mg)
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSMB00586
  • Product descriptionNimbolide from Azadirachta indica, ≥98%
  • Packaging5MG
  • Price₹45811.4
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SMB00586 Nimbolide from Azadirachta indica, ≥98% 5MG ₹45811.4 2022-06-14 Buy

Properties

Melting point :>223°C (dec.)
Boiling point :608.6±55.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :Chloroform, Ethyl Acetate
form :powder
color :Light Beige to Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Nimbolide, a natural triterpenoid present in the edible parts of the neem tree (Azadirachta indica), was found to be growth-inhibitory in human colon carcinoma HT-29 cells. Nimbolide treatment of cells at 2.5 - 10 μM resulted in moderate to very strong growth inhibition.

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