OLOMOUCINE
- ₹5880 - ₹32702.33
- Product name: OLOMOUCINE
- CAS: 101622-51-9
- MF: C15H18N6O
- MW: 298.34
- EINECS:
- MDL Number:MFCD00189360
- Synonyms:6-BENYLAMINO-2-(2-HYDROXYETHYLAMINO)-9-METHYLPURINE;6-BENZYLAMINO-2-(2-HYDROXYETHYLAMINO)-9-METHYLPURINE;2-(2'-Hydroxyethylamino)-9-methyl-6-(benzylamino)purine;2-(hydroxyethylamino)-6-benzylamino-9-methylpurine;2-[[9-METHYL-6[(PHENYLMETHYL)AMINO]-9H-PURIN-2-YL]AMINO]-ETHANOL;2-(2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-METHYLPURINE;N2-[(2-HYDROXYETHYL)]-N6-BENZYLADENINE;OLOMOUCINE
4 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product number495620
- Product descriptionOlomoucine - CAS 101622-51-9 - Calbiochem A purine derivative that acts as a potent, reversible and selective inhibitor of p34cdk1/cyclin B and related kinases.
- Packaging1MG
- Price₹5880
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberO0886
- Product descriptionOlomoucine ≥98% (HPLC)
- Packaging1MG
- Price₹8887.33
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number495620
- Product descriptionOlomoucine - CAS 101622-51-9 - Calbiochem A purine derivative that acts as a potent, reversible and selective inhibitor of p34cdk1/cyclin B and related kinases.
- Packaging5MG
- Price₹22650
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberO0886
- Product descriptionOlomoucine ≥98% (HPLC)
- Packaging5MG
- Price₹32702.33
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 495620 | Olomoucine - CAS 101622-51-9 - Calbiochem A purine derivative that acts as a potent, reversible and selective inhibitor of p34cdk1/cyclin B and related kinases. | 1MG | ₹5880 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | O0886 | Olomoucine ≥98% (HPLC) | 1MG | ₹8887.33 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 495620 | Olomoucine - CAS 101622-51-9 - Calbiochem A purine derivative that acts as a potent, reversible and selective inhibitor of p34cdk1/cyclin B and related kinases. | 5MG | ₹22650 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | O0886 | Olomoucine ≥98% (HPLC) | 5MG | ₹32702.33 | 2022-06-14 | Buy |
Properties
Melting point :120-130 °C
Boiling point :579.6±60.0 °C(Predicted)
Density :1.36
storage temp. :-20°C
solubility :DMSO, Methanol (Slightly)
pka :14.55±0.10(Predicted)
form :Solid
color :White to off-white
CAS DataBase Reference :101622-51-9(CAS DataBase Reference)
Boiling point :579.6±60.0 °C(Predicted)
Density :1.36
storage temp. :-20°C
solubility :DMSO, Methanol (Slightly)
pka :14.55±0.10(Predicted)
form :Solid
color :White to off-white
CAS DataBase Reference :101622-51-9(CAS DataBase Reference)
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Olomoucine is a purine that acts as a competitive inhibitor of a variety of cell cycle regulating proteins with high specificity, which leads to the blockage of some cell cycle steps. The compound inhibits: Cdc2/cyclin B, Cdk2/cyclin A and Cdk2/cyclin E kinases, the brain Cdk5/p35 kinase and the ERK1/MAP-kinase. Olomoucine does not significantly inhibit Cdk4/cyclin D1 and Cdk6/cyclin D3 kinases. The compound can induce cell arrest at G1/S and the G2/M, due to its effect on Ckd2 and Cdcd2. Olomoucine also behaves as a competitive inhibitor for ATP and as a non-competitive inhibitor for histone H1 in terms of being Cdk substrates.More related product prices
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