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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antiviral drugs >Stavudine

Stavudine

Stavudine Structure
  • ₹8670.83 - ₹33958.03
  • Product name: Stavudine
  • CAS: 3056-17-5
  • MF: C10H12N2O4
  • MW: 224.21
  • EINECS:641-374-0
  • MDL Number:MFCD00132921
  • Synonyms:STAVUDINE;3'-deoxythymidin-2'-ene;3'-DEOXY-2',3'-DIDEHYDROTHYMIDINE;ZERIT;STAVUDINE[2'',3''-DIDEHYDRO-3''-DEOXYTHYMIDINE];NSC 163661;Stavir;Thymidine, 2'', 3''-didehydro-3''-deoxy-
4 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberD3580
  • Product description2',3'-Didehydro-3'-deoxythymidine
  • Packaging1G
  • Price₹10800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD3580
  • Product description2',3'-Didehydro-3'-deoxythymidine
  • Packaging5G
  • Price₹14500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD1413
  • Product description2′,3′-Didehydro-3′-deoxythymidine ≥98% (TLC)
  • Packaging10MG
  • Price₹8670.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD1413
  • Product description2′,3′-Didehydro-3′-deoxythymidine ≥98% (TLC)
  • Packaging50MG
  • Price₹33958.03
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D3580 2',3'-Didehydro-3'-deoxythymidine 1G ₹10800 2022-05-26 Buy
TCI Chemicals (India) D3580 2',3'-Didehydro-3'-deoxythymidine 5G ₹14500 2022-05-26 Buy
Sigma-Aldrich(India) D1413 2′,3′-Didehydro-3′-deoxythymidine ≥98% (TLC) 10MG ₹8670.83 2022-06-14 Buy
Sigma-Aldrich(India) D1413 2′,3′-Didehydro-3′-deoxythymidine ≥98% (TLC) 50MG ₹33958.03 2022-06-14 Buy

Properties

Melting point :159-160°C
alpha :D25 -39.4° (c = 0.701 in water); D20 -46.1° (c = 0.7 in water)
Density :1.374±0.06 g/cm3(Predicted)
refractive index :-46 ° (C=0.69, H2O)
storage temp. :-20°C
solubility :Soluble in water, sparingly soluble in ethanol (96 per cent), slightly soluble in methylene chloride. It shows polymorphism (5.9).
form :Solid
pka :9.47±0.10(Predicted)
color :White
Water Solubility :5-10 g/100 mL at 21 ºC
BCS Class :1,3
Stability :Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey :XNKLLVCARDGLGL-JGVFFNPUSA-N
CAS DataBase Reference :3056-17-5(CAS DataBase Reference)
EPA Substance Registry System :Thymidine, 2',3'-didehydro-3'-deoxy- (3056-17-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Stavudine is an analog of thymidine that, following phosphorylation by cellular kinases, inhibits the reverse transcriptase of human immunodeficiency virus. It is effective in vitro and in vivo, orally available, and additive in action with protease inhibitors. Adverse events associated with stavudine use include peripheral neuropathy, lactic acidosis, and pancreatitis.

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