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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antifungal Drugs >Terbinafine

Terbinafine

Terbinafine Structure
  • ₹2200 - ₹4100
  • Product name: Terbinafine
  • CAS: 91161-71-6
  • MF: C21H25N
  • MW: 291.43
  • EINECS:618-706-8
  • MDL Number:MFCD00242672
  • Synonyms:trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine;(e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamine ;6-dimethyl-2-hepten-4-ynyl)-n-methyl-n-((e)-1-naphthalenemethanamin ;sf-86-327 ;TERBINAFINE;1-Naphthalenemethanamine, N-(2E)-6,6-dimethyl-2-hepten-4-ynyl-N-methyl-;(E)-N-(6，6-I)imethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine;rerbinafine
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • TCI Chemicals (India)

Package

  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberT3677
  • Product descriptionTerbinafine
  • Packaging1G
  • Price₹2200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT3677
  • Product descriptionTerbinafine
  • Packaging5G
  • Price₹4100
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T3677 Terbinafine 1G ₹2200 2022-05-26 Buy
TCI Chemicals (India) T3677 Terbinafine 5G ₹4100 2022-05-26 Buy

Properties

Melting point :203-205 °C
Boiling point :417.9±33.0 °C(Predicted)
Density :1.007±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 25℃
storage temp. :2-8°C
solubility :soluble in Methanol
form :powder to crystal
pka :6.92±0.50(Predicted)
color :White to Light yellow
LogP :3.3 at 37℃ and pH7
CAS DataBase Reference :91161-71-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Terbinafine (Lamisil) is a second-generation allylamine that is related to naftifine; however, it is 10 to 100 times more potent in vitro. It is fungicidal, whereas griseofulvin, ketoconazole, itraconazole, and other azole derivatives are all fungistatic. Because it is fungicidal, duration of therapy is shorter, and relapse rates are less than with other oral or topical therapies. Terbinafine acts by inhibiting squalene epoxidase and thereby decreasing synthesis of ergosterol, an essential component of fungal cell membranes. It is highly lipophilic and concentrates in the stratum corneum, sebum, and hair follicles. Slightly better cure rates are attained with b.i.d. than with daily dosing.
Lamisil (Novartis) Tablets

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Suppliers and manufacturers

Meenaakshi Molecules Pvt Ltd Lakshmi Farmachem Chempifine Chemicals Shamrock Medicaments Ltd. Besil Chem LLP Tivan Sciences Pvt Ltd Ralington Pharma Sibram Pharmaceutical Suvan LifeSciences (formerly Sansh Biotech Pvt Ltd) OCEAN TRADING CORPORATION