α-Naphthoflavone
- ₹730 - ₹25679
- Product name: α-Naphthoflavone
- CAS: 604-59-1
- MF: C19H12O2
- MW: 272.3
- EINECS:210-071-1
- MDL Number:MFCD00004985
- Synonyms:7,8-BENZOFLAVONE;ALPHA-NAPHTHOFLAVONE;A-NAPHTHOFLAVANONE;A-NAPHTHOFLAVONE;BENZOFLAVONE;NAPHTHOFLAVANONE, A-;NAPHTHOFLAVONE, A-;2-b)pyran-4-one,2-phenyl-4h-naphtho(
9 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
- ALFA India
- SRL
Package
- 1G
- 5G
- 25g
- 1Gms
- 5Gms
- 25Gms
- ManufacturerTCI Chemicals (India)
- Product numberB0056
- Product descriptionα-Naphthoflavone
- Packaging1G
- Price₹2000
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberB0056
- Product descriptionα-Naphthoflavone
- Packaging5G
- Price₹2900
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberN5757
- Product descriptionα-Naphthoflavone ≥98%
- Packaging1G
- Price₹4503.2
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberN5757
- Product descriptionα-Naphthoflavone ≥98%
- Packaging5G
- Price₹5423.33
- Updated2022-06-14
- Buy
- ManufacturerALFA India
- Product numberALF-A18542-14
- Product descriptionalpha-Naphthoflavone, 97%
- Packaging25g
- Price₹25679
- Updated2022-05-26
- Buy
- ManufacturerALFA India
- Product numberALF-A18542-06
- Product descriptionalpha-Naphthoflavone, 97%
- Packaging5g
- Price₹5135
- Updated2022-05-26
- Buy
- ManufacturerSRL
- Product number57955
- Product descriptiona-Naphthoflavone extrapure AR, 98%
- Packaging1Gms
- Price₹730
- Updated2022-05-26
- Buy
- ManufacturerSRL
- Product number57955
- Product descriptiona-Naphthoflavone extrapure AR, 98%
- Packaging5Gms
- Price₹2650
- Updated2022-05-26
- Buy
- ManufacturerSRL
- Product number57955
- Product descriptiona-Naphthoflavone extrapure AR, 98%
- Packaging25Gms
- Price₹12040
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | B0056 | α-Naphthoflavone | 1G | ₹2000 | 2022-05-26 | Buy |
TCI Chemicals (India) | B0056 | α-Naphthoflavone | 5G | ₹2900 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | N5757 | α-Naphthoflavone ≥98% | 1G | ₹4503.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | N5757 | α-Naphthoflavone ≥98% | 5G | ₹5423.33 | 2022-06-14 | Buy |
ALFA India | ALF-A18542-14 | alpha-Naphthoflavone, 97% | 25g | ₹25679 | 2022-05-26 | Buy |
ALFA India | ALF-A18542-06 | alpha-Naphthoflavone, 97% | 5g | ₹5135 | 2022-05-26 | Buy |
SRL | 57955 | a-Naphthoflavone extrapure AR, 98% | 1Gms | ₹730 | 2022-05-26 | Buy |
SRL | 57955 | a-Naphthoflavone extrapure AR, 98% | 5Gms | ₹2650 | 2022-05-26 | Buy |
SRL | 57955 | a-Naphthoflavone extrapure AR, 98% | 25Gms | ₹12040 | 2022-05-26 | Buy |
Properties
Melting point :153-157 °C (lit.)
Boiling point :375.35°C (rough estimate)
Density :1.1382 (rough estimate)
refractive index :1.5510 (estimate)
storage temp. :2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Crystalline Powder or Crystals
color :yellow
BRN :210862
Stability :Stable. Incompatible with strong oxidizing agents.
LogP :5.003 (est)
CAS DataBase Reference :604-59-1(CAS DataBase Reference)
EPA Substance Registry System :4H-Naphtho[1,2-b]pyran-4-one, 2-phenyl- (604-59-1)
Boiling point :375.35°C (rough estimate)
Density :1.1382 (rough estimate)
refractive index :1.5510 (estimate)
storage temp. :2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Crystalline Powder or Crystals
color :yellow
BRN :210862
Stability :Stable. Incompatible with strong oxidizing agents.
LogP :5.003 (est)
CAS DataBase Reference :604-59-1(CAS DataBase Reference)
EPA Substance Registry System :4H-Naphtho[1,2-b]pyran-4-one, 2-phenyl- (604-59-1)
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
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Description
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. α-Naphthoflavone is a flavone that modulates xenobiotic metabolism at several points. It antagonizes AhR, blocking the expression of phase I and II genes at nanomolar concentrations, although it can agonize AhR at higher concentrations (10 μM). α-Naphthoflavone inhibits CYP19 (aromatase), CYP1A1, CYP1A2, and CYP1B1 (IC50s = 500, 60, 6, and 5 nM, respectively), whereas it activates CYP3A4 (Kd = 7.4 μM). Dietary α-naphthoflavone can contribute to carcinogenesis in the presence of synthetic estrogens.More related product prices
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