1,7-DIMETHYLXANTHINE
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- $44 - $2480
- Product name: 1,7-DIMETHYLXANTHINE
- CAS: 611-59-6
- MF: C7H8N4O2
- MW: 180.16
- EINECS:210-271-9
- MDL Number:MFCD00005727
- Synonyms:1,7-dimethyl-3H-purine-2,6-dione;1,7-Dimethyl-1H-purine-2,6-dione, 2,6-Dihydroxy-1,7-dimethylpurine, Paraxanthine;1,7-Dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione;1,7-Dimethylxanthine-[13C4,15N3] (para-xanthine);1,7-Dimethylxanthine-[2H6] (para-xanthine);Paraxanthine-d3;IMp. F (EP): 1,7-DiMethyl-3,7-dihydro-1H-purine-2,6-dione(Paraxanthine;Caffeine IMpurity F
21 prices
Selected condition：
Brand
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 1mg
- 10mg
- 25mg
- 50mg
- 100mg
- 500mg
- 1mL
- 1G
- 25g
- ManufacturerAHH
- Product numberMT-11097
- Product description1,7-Dimethylxanthine 96%
- Packaging25g
- Price$898
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number0147BA
- Product descriptionParaxanthine
- Packaging100mg
- Price$289
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008865
- Product descriptionPARAXANTHINE 95.00%
- Packaging100MG
- Price$315
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008865
- Product descriptionPARAXANTHINE 95.00%
- Packaging1G
- Price$1871.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21068
- Product descriptionParaxanthine ≥98%
- Packaging10mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21068
- Product descriptionParaxanthine ≥98%
- Packaging25mg
- Price$82
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21068
- Product descriptionParaxanthine ≥98%
- Packaging50mg
- Price$118
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21068
- Product descriptionParaxanthine ≥98%
- Packaging100mg
- Price$172
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-W017214
- Product descriptionParaxanthine 99.95%
- Packaging25mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-W017214
- Product descriptionParaxanthine 99.95%
- Packaging50mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-W017214
- Product descriptionParaxanthine 99.95%
- Packaging100mg
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product numberD71893
- Product descriptionParaxanthine-d3
- Packaging10mg
- Price$2480
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberIMPC-051-03
- Product descriptionParaxanthine solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging1mL
- Price$66.4
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberD5385
- Product description1,7-Dimethylxanthine ~98%, solid
- Packaging100mg
- Price$210
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberD5385
- Product description1,7-Dimethylxanthine ~98%, solid
- Packaging500mg
- Price$333.6
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberPHR2000
- Product descriptionCaffeine Impurity F Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging50MG
- Price$564
- Updated2022-05-15
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-11097 | 1,7-Dimethylxanthine 96% | 25g | $898 | 2021-12-16 | Buy |
| AK Scientific | 0147BA | Paraxanthine | 100mg | $289 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008865 | PARAXANTHINE 95.00% | 100MG | $315 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008865 | PARAXANTHINE 95.00% | 1G | $1871.1 | 2021-12-16 | Buy |
| Cayman Chemical | 21068 | Paraxanthine ≥98% | 10mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 21068 | Paraxanthine ≥98% | 25mg | $82 | 2024-03-01 | Buy |
| Cayman Chemical | 21068 | Paraxanthine ≥98% | 50mg | $118 | 2024-03-01 | Buy |
| Cayman Chemical | 21068 | Paraxanthine ≥98% | 100mg | $172 | 2024-03-01 | Buy |
| ChemScene | CS-W017214 | Paraxanthine 99.95% | 25mg | $70 | 2021-12-16 | Buy |
| ChemScene | CS-W017214 | Paraxanthine 99.95% | 50mg | $100 | 2021-12-16 | Buy |
| ChemScene | CS-W017214 | Paraxanthine 99.95% | 100mg | $145 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | D71893 | Paraxanthine-d3 | 10mg | $2480 | 2021-12-16 | Buy |
| Sigma-Aldrich | IMPC-051-03 | Paraxanthine solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | 1mL | $66.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | D5385 | 1,7-Dimethylxanthine ~98%, solid | 100mg | $210 | 2024-03-01 | Buy |
| Sigma-Aldrich | D5385 | 1,7-Dimethylxanthine ~98%, solid | 500mg | $333.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHR2000 | Caffeine Impurity F Pharmaceutical Secondary Standard; Certified Reference Material | 50MG | $564 | 2022-05-15 | Buy |
Properties
Melting point :294-296 °C (lit.)
Boiling point :312.97°C (rough estimate)
Density :1.3640 (rough estimate)
refractive index :1.6700 (estimate)
Flash point :9℃
storage temp. :room temp
solubility :ethanol: 0.6mg/mL
form :solid
pka :pKa 8.5 (Uncertain)
color :white
BRN :197907
Stability :Store tightly sealed at RT
InChI :InChI=1S/C7H8N4O2/c1-10-3-8-5-4(10)6(12)11(2)7(13)9-5/h3H,1-2H3,(H,9,13)
InChIKey :QUNWUDVFRNGTCO-UHFFFAOYSA-N
SMILES :N1(C)C2=C(NC(=O)N(C)C2=O)N=C1
EPA Substance Registry System :1H-Purine-2,6-dione, 3,7-dihydro-1,7-dimethyl- (611-59-6)
Boiling point :312.97°C (rough estimate)
Density :1.3640 (rough estimate)
refractive index :1.6700 (estimate)
Flash point :9℃
storage temp. :room temp
solubility :ethanol: 0.6mg/mL
form :solid
pka :pKa 8.5 (Uncertain)
color :white
BRN :197907
Stability :Store tightly sealed at RT
InChI :InChI=1S/C7H8N4O2/c1-10-3-8-5-4(10)6(12)11(2)7(13)9-5/h3H,1-2H3,(H,9,13)
InChIKey :QUNWUDVFRNGTCO-UHFFFAOYSA-N
SMILES :N1(C)C2=C(NC(=O)N(C)C2=O)N=C1
EPA Substance Registry System :1H-Purine-2,6-dione, 3,7-dihydro-1,7-dimethyl- (611-59-6)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Paraxanthine is an inhibitor of phosphodiesterase 9 (PDE9) and an antagonist of adenosine receptors A1 and A2 (Kis = 35 and 22 μM, respectively in equine forebrain tissues). It is the main metabolite of caffeine in humans, making up 80% of the three dimethylxanthine metabolites produced by caffeine demethylation. Paraxanthine increases locomotor activity and counteracts adenosine receptor agonist-induced motor depression in rats not habituated to caffeine. At a dose of 30 mg/kg, paraxanthine induces a significant increase in striatal cGMP and extracellular striatal dopamine concentrations in vivo. It also promotes wakefulness and increases locomotor activity and core temperature in narcoleptic transgenic mice without increasing behavioral anxiety.More related product prices
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