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ChemicalBook >> CAS DataBase List >> 1,9-Pyrazoloanthrone

1,9-Pyrazoloanthrone

1,9-Pyrazoloanthrone price.
  • $5 - $1390
  • Product name: 1,9-Pyrazoloanthrone
  • CAS: 129-56-6
  • MF: C14H8N2O
  • MW: 220.23
  • EINECS:204-955-6
  • MDL Number:MFCD00022289
  • Synonyms:Dibenzo[cd,g]indazol-6(2H)-one;Nsc75890;Wln: T C6665 1A p iv omnj;SP600125 >99%;JNK Inhibitor II, 1,9-Pyrazoloanthrone;c.i.70300 ;SAPK INHIBITOR I;SAPK INHIBITOR II
57 prices
Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 5MG
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 10
  • 50
  • 250mg
  • 500mg
  • 1g
  • 2g
  • 2.5G
  • 5g
  • 10g
  • 25g
  • ManufacturerAHH
  • Product numberMT-21875
  • Product description1,9-Pyrazoloanthrone 98%
  • Packaging5g
  • Price$388
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51570
  • Product description1,9-Pyrazoloanthrone
  • Packaging5g
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberK914
  • Product description1,9-Pyrazoloanthrone
  • Packaging5g
  • Price$74
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51570
  • Product description1,9-Pyrazoloanthrone
  • Packaging10g
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51570
  • Product description1,9-Pyrazoloanthrone
  • Packaging25g
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67272
  • Product descriptionSP600125 99%
  • Packaging50mg
  • Price$126
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67272
  • Product descriptionSP600125 99%
  • Packaging100mg
  • Price$217
  • Updated2023-06-20
  • Buy
  • ManufacturerAmbeed
  • Product numberA155219
  • Product descriptionSP-600125 98+%
  • Packaging10mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA155219
  • Product descriptionSP-600125 98+%
  • Packaging50mg
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA155219
  • Product descriptionSP-600125 98+%
  • Packaging100mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA155219
  • Product descriptionSP-600125 98+%
  • Packaging250mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA155219
  • Product descriptionSP-600125 98+%
  • Packaging1g
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA155219
  • Product descriptionSP-600125 98+%
  • Packaging5g
  • Price$186
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000236
  • Product description1,9-PYRAZOLOANTHRONE 95.00%
  • Packaging5MG
  • Price$501
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000236
  • Product description1,9-PYRAZOLOANTHRONE 95.00%
  • Packaging1G
  • Price$692.46
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000236
  • Product description1,9-PYRAZOLOANTHRONE 95.00%
  • Packaging2.5G
  • Price$932.6
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-21875 1,9-Pyrazoloanthrone 98% 5g $388 2021-12-16 Buy
AK Scientific J51570 1,9-Pyrazoloanthrone 5g $55 2021-12-16 Buy
AK Scientific K914 1,9-Pyrazoloanthrone 5g $74 2021-12-16 Buy
AK Scientific J51570 1,9-Pyrazoloanthrone 10g $90 2021-12-16 Buy
AK Scientific J51570 1,9-Pyrazoloanthrone 25g $170 2021-12-16 Buy
Alfa Aesar J67272 SP600125 99% 50mg $126 2023-06-20 Buy
Alfa Aesar J67272 SP600125 99% 100mg $217 2023-06-20 Buy
Ambeed A155219 SP-600125 98+% 10mg $5 2021-12-16 Buy
Ambeed A155219 SP-600125 98+% 50mg $16 2021-12-16 Buy
Ambeed A155219 SP-600125 98+% 100mg $30 2021-12-16 Buy
Ambeed A155219 SP-600125 98+% 250mg $45 2021-12-16 Buy
Ambeed A155219 SP-600125 98+% 1g $110 2021-12-16 Buy
Ambeed A155219 SP-600125 98+% 5g $186 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000236 1,9-PYRAZOLOANTHRONE 95.00% 5MG $501 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000236 1,9-PYRAZOLOANTHRONE 95.00% 1G $692.46 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000236 1,9-PYRAZOLOANTHRONE 95.00% 2.5G $932.6 2021-12-16 Buy

Properties

Melting point :281~282℃
Boiling point :361.16°C (rough estimate)
Density :1.1702 (rough estimate)
refractive index :1.5910 (estimate)
storage temp. :2-8°C
solubility :H2O: insoluble
form :Yellowish orange solid
pka :11.75±0.20(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
InChIKey :ACPOUJIDANTYHO-UHFFFAOYSA-N
CAS DataBase Reference :129-56-6(CAS DataBase Reference)
EPA Substance Registry System :Anthra[1,9-cd]pyrazol-6(2H)-one (129-56-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

SP 600125 is a potent and reversible inhibitor of JNK1-3 with an IC50 value of 0.11 ?M.1 It is cell-permeable and dose-dependently inhibits c-Jun phosphorylation in cells, blocking the expression of COX-2 and TNF-α in monocytes and IL-10, TNF-α, and IFN-γ in T-cells. SP 600125 also prevents apoptosis in many cell types, including B-cells, and inhibits autophagy in HeLa cells. Competitively and reversibly inhibits JNK1, 2 and 3 (IC50 = 40 - 90 nM) with negligible activity at ERK2, p38β and a range of enzymes (IC50 > 10 ?M). Active in vivo. Shown to have reduced selectivity over other protein kinases under certain conditions. Protects renal tubular epithelial cells against ischemia/reperfusion-induced apoptosis. Prevents BMP9-induced osteogenic differentiation of MSCs.

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