1,9-Pyrazoloanthrone
- $5 - $1390
- Product name: 1,9-Pyrazoloanthrone
- CAS: 129-56-6
- MF: C14H8N2O
- MW: 220.23
- EINECS:204-955-6
- MDL Number:MFCD00022289
- Synonyms:Dibenzo[cd,g]indazol-6(2H)-one;Nsc75890;Wln: T C6665 1A p iv omnj;SP600125 >99%;JNK Inhibitor II, 1,9-Pyrazoloanthrone;c.i.70300 ;SAPK INHIBITOR I;SAPK INHIBITOR II
57 prices
Brand
- AHH
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 5MG
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 200mg
- 10
- 50
- 250mg
- 500mg
- 1g
- 2g
- 2.5G
- 5g
- 10g
- 25g
- ManufacturerAHH
- Product numberMT-21875
- Product description1,9-Pyrazoloanthrone 98%
- Packaging5g
- Price$388
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ51570
- Product description1,9-Pyrazoloanthrone
- Packaging5g
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberK914
- Product description1,9-Pyrazoloanthrone
- Packaging5g
- Price$74
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ51570
- Product description1,9-Pyrazoloanthrone
- Packaging10g
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ51570
- Product description1,9-Pyrazoloanthrone
- Packaging25g
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67272
- Product descriptionSP600125 99%
- Packaging50mg
- Price$126
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67272
- Product descriptionSP600125 99%
- Packaging100mg
- Price$217
- Updated2023-06-20
- Buy
- ManufacturerAmbeed
- Product numberA155219
- Product descriptionSP-600125 98+%
- Packaging10mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA155219
- Product descriptionSP-600125 98+%
- Packaging50mg
- Price$16
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA155219
- Product descriptionSP-600125 98+%
- Packaging100mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA155219
- Product descriptionSP-600125 98+%
- Packaging250mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA155219
- Product descriptionSP-600125 98+%
- Packaging1g
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA155219
- Product descriptionSP-600125 98+%
- Packaging5g
- Price$186
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000236
- Product description1,9-PYRAZOLOANTHRONE 95.00%
- Packaging5MG
- Price$501
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000236
- Product description1,9-PYRAZOLOANTHRONE 95.00%
- Packaging1G
- Price$692.46
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000236
- Product description1,9-PYRAZOLOANTHRONE 95.00%
- Packaging2.5G
- Price$932.6
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AHH | MT-21875 | 1,9-Pyrazoloanthrone 98% | 5g | $388 | 2021-12-16 | Buy |
AK Scientific | J51570 | 1,9-Pyrazoloanthrone | 5g | $55 | 2021-12-16 | Buy |
AK Scientific | K914 | 1,9-Pyrazoloanthrone | 5g | $74 | 2021-12-16 | Buy |
AK Scientific | J51570 | 1,9-Pyrazoloanthrone | 10g | $90 | 2021-12-16 | Buy |
AK Scientific | J51570 | 1,9-Pyrazoloanthrone | 25g | $170 | 2021-12-16 | Buy |
Alfa Aesar | J67272 | SP600125 99% | 50mg | $126 | 2023-06-20 | Buy |
Alfa Aesar | J67272 | SP600125 99% | 100mg | $217 | 2023-06-20 | Buy |
Ambeed | A155219 | SP-600125 98+% | 10mg | $5 | 2021-12-16 | Buy |
Ambeed | A155219 | SP-600125 98+% | 50mg | $16 | 2021-12-16 | Buy |
Ambeed | A155219 | SP-600125 98+% | 100mg | $30 | 2021-12-16 | Buy |
Ambeed | A155219 | SP-600125 98+% | 250mg | $45 | 2021-12-16 | Buy |
Ambeed | A155219 | SP-600125 98+% | 1g | $110 | 2021-12-16 | Buy |
Ambeed | A155219 | SP-600125 98+% | 5g | $186 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000236 | 1,9-PYRAZOLOANTHRONE 95.00% | 5MG | $501 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000236 | 1,9-PYRAZOLOANTHRONE 95.00% | 1G | $692.46 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000236 | 1,9-PYRAZOLOANTHRONE 95.00% | 2.5G | $932.6 | 2021-12-16 | Buy |
Properties
Melting point :281~282℃
Boiling point :361.16°C (rough estimate)
Density :1.1702 (rough estimate)
refractive index :1.5910 (estimate)
storage temp. :2-8°C
solubility :H2O: insoluble
form :Yellowish orange solid
pka :11.75±0.20(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
InChIKey :ACPOUJIDANTYHO-UHFFFAOYSA-N
CAS DataBase Reference :129-56-6(CAS DataBase Reference)
EPA Substance Registry System :Anthra[1,9-cd]pyrazol-6(2H)-one (129-56-6)
Boiling point :361.16°C (rough estimate)
Density :1.1702 (rough estimate)
refractive index :1.5910 (estimate)
storage temp. :2-8°C
solubility :H2O: insoluble
form :Yellowish orange solid
pka :11.75±0.20(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
InChIKey :ACPOUJIDANTYHO-UHFFFAOYSA-N
CAS DataBase Reference :129-56-6(CAS DataBase Reference)
EPA Substance Registry System :Anthra[1,9-cd]pyrazol-6(2H)-one (129-56-6)
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||
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Precautionary statements: |
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Description
SP 600125 is a potent and reversible inhibitor of JNK1-3 with an IC50 value of 0.11 ?M.1 It is cell-permeable and dose-dependently inhibits c-Jun phosphorylation in cells, blocking the expression of COX-2 and TNF-α in monocytes and IL-10, TNF-α, and IFN-γ in T-cells. SP 600125 also prevents apoptosis in many cell types, including B-cells, and inhibits autophagy in HeLa cells. Competitively and reversibly inhibits JNK1, 2 and 3 (IC50 = 40 - 90 nM) with negligible activity at ERK2, p38β and a range of enzymes (IC50 > 10 ?M). Active in vivo. Shown to have reduced selectivity over other protein kinases under certain conditions. Protects renal tubular epithelial cells against ischemia/reperfusion-induced apoptosis. Prevents BMP9-induced osteogenic differentiation of MSCs.Related product price
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Hubei Jusheng Technology Co.,Ltd.
Alchem Pharmtech,Inc.
CONIER CHEM AND PHARMA LIMITED