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ChemicalBook >> CAS DataBase List >> Faropenem sodium hemipentahydrate

Faropenem sodium hemipentahydrate

Faropenem sodium hemipentahydrate price.
  • $39 - $927.76
  • Product name: Faropenem sodium hemipentahydrate
  • CAS: 106560-14-9
  • MF: C12H15NO5S
  • MW: 285.32
  • EINECS:1312995-182-4
  • MDL Number:MFCD00868867
  • Synonyms:[5R-[3(R^<*>^),5α,6α(R^<*>^)]]-6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-4-thia-1-azobicyclo[3.2.0]leapt-2- ene-2-carboxylicacid;(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-keto-3-[(2R)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid;(+)-(5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;(5R,6S,8R,2'R)-2-(2'-tetrahydrofuryl)-6-(1-hydroxyethyl)-2-penem-3-carboxylic acid;4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-, [5R-[3(R*),5α,6α(R*)]]-;4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-, (5R,6S)-
6 prices
Selected condition:
Brand
  • AHH
  • American Custom Chemicals Corporation
  • AvaChem
  • TRC
Package
  • 10mg
  • 100mg
  • 1g
  • 5G
  • ManufacturerAHH
  • Product numberAPI-1035
  • Product descriptionFropenem 98%
  • Packaging100mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002771
  • Product descriptionFROPENEM 95.00%
  • Packaging5G
  • Price$927.76
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1723A
  • Product descriptionFaropenem
  • Packaging10mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1723A
  • Product descriptionFaropenem
  • Packaging100mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1723A
  • Product descriptionFaropenem
  • Packaging1g
  • Price$279
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberF103303
  • Product descriptionFaropenem
  • Packaging100mg
  • Price$580
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1035 Fropenem 98% 100mg $600 2021-12-16 Buy
American Custom Chemicals Corporation API0002771 FROPENEM 95.00% 5G $927.76 2021-12-16 Buy
AvaChem 1723A Faropenem 10mg $39 2021-12-16 Buy
AvaChem 1723A Faropenem 100mg $89 2021-12-16 Buy
AvaChem 1723A Faropenem 1g $279 2021-12-16 Buy
TRC F103303 Faropenem 100mg $580 2021-12-16 Buy

Properties

Boiling point :570.2±50.0 °C(Predicted)
Density :1.56±0.1 g/cm3(Predicted)
pka :4.00±0.40(Predicted)
CAS DataBase Reference :106560-14-9

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Farom was launched in Japan for use as an antibiotic against common respiratory tract pathogens. It can be prepared by several related routes of about seven steps starting with tetrahydrofuran-2-thiocarboxylic acid and a silylated azetidinone. It is a broad spectrum oral penem antibiotic that is β-lactamase stable. Farom is the most active β-lactam against anaerobes (more than cefaclor, cefixime and amoxicillin) but also has activity against Gram-positive, Gram-negative and enterobacteriaceae. It is equally active against strains carrying plasmid and chromosome mediated β-lactamases. The short plasma elimination half-life is the result of hydrolysis by renal dehydropeptidase. It is more stable to hydrolysis by extended spectrum β-lactamases than some second and third generation cephalosporins.

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