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ChemicalBook >> CAS DataBase List >> 1-[5-ETHYL-2-HYDROXY-4-[[6-METHYL-6-(1H-TETRAZOL-5-YL)HEPTYL]OXY]PHENYL]ETHANONE

1-[5-ETHYL-2-HYDROXY-4-[[6-METHYL-6-(1H-TETRAZOL-5-YL)HEPTYL]OXY]PHENYL]ETHANONE

1-[5-ETHYL-2-HYDROXY-4-[[6-METHYL-6-(1H-TETRAZOL-5-YL)HEPTYL]OXY]PHENYL]ETHANONE price.
  • $25 - $2984
  • Product name: 1-[5-ETHYL-2-HYDROXY-4-[[6-METHYL-6-(1H-TETRAZOL-5-YL)HEPTYL]OXY]PHENYL]ETHANONE
  • CAS: 117690-79-6
  • MF: C19H28N4O3
  • MW: 360.45
  • EINECS:
  • MDL Number:MFCD00876422
  • Synonyms:LY 255283;1-[5-ETHYL-2-HYDROXY-4-[[6-METHYL-6-(1H-TETRAZOL-5-YL)HEPTYL]OXY]PHENYL]ETHANONE;1-[5-ETHYL-2-HYDROXY-4-[[6-METHYL-6-(1H-TETRAZOLE-5-YL)HEPTYL]OXY]PHENYL]-ETHANONE;5'-Ethyl-2'-hydroxy-4'-[6-methyl-6-(1H-tetrazol-5-yl)heptyloxy]acetophenone;CGS 23356;1-[5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-tetrazol-5-yl)heptoxy]phenyl]ethanone;Ethanone, 1-[5-ethyl-2-hydroxy-4-[[6-methyl-6-(2H-tetrazol-5-yl)heptyl]oxy]phenyl]-;1-(5-Ethyl-2-hydroxy-4-((6-methyl-6-(2H-tetrazol-5-yl)heptyl)oxy)phenyl)ethan-1-one
24 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1MG
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number1134AH
  • Product description1-[5-Ethyl-2-hydroxy-4-[[6-methyl-6-(1h-tetrazol-5-yl)heptyl]oxy]phenyl]ethanone
  • Packaging25mg
  • Price$388
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA646553
  • Product descriptionLy255283 98+%
  • Packaging5mg
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA646553
  • Product descriptionLy255283 98+%
  • Packaging10mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA646553
  • Product descriptionLy255283 98+%
  • Packaging25mg
  • Price$315
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA646553
  • Product descriptionLy255283 98+%
  • Packaging50mg
  • Price$608
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA646553
  • Product descriptionLy255283 98+%
  • Packaging100mg
  • Price$796
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA646553
  • Product descriptionLy255283 98+%
  • Packaging250mg
  • Price$1193
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA646553
  • Product descriptionLy255283 98+%
  • Packaging1g
  • Price$2984
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008308
  • Product descriptionLY-255283 95.00%
  • Packaging1MG
  • Price$215.25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008308
  • Product descriptionLY-255283 95.00%
  • Packaging5MG
  • Price$658.12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008308
  • Product descriptionLY-255283 95.00%
  • Packaging25MG
  • Price$791.93
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6978
  • Product descriptionLY255283
  • Packaging10mg
  • Price$282
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6978
  • Product descriptionLY255283
  • Packaging50mg
  • Price$1190
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number70715
  • Product descriptionLY255283 ≥98%
  • Packaging1mg
  • Price$25
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70715
  • Product descriptionLY255283 ≥98%
  • Packaging5mg
  • Price$94
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70715
  • Product descriptionLY255283 ≥98%
  • Packaging10mg
  • Price$140
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1134AH 1-[5-Ethyl-2-hydroxy-4-[[6-methyl-6-(1h-tetrazol-5-yl)heptyl]oxy]phenyl]ethanone 25mg $388 2021-12-16 Buy
Ambeed A646553 Ly255283 98+% 5mg $86 2021-12-16 Buy
Ambeed A646553 Ly255283 98+% 10mg $144 2021-12-16 Buy
Ambeed A646553 Ly255283 98+% 25mg $315 2021-12-16 Buy
Ambeed A646553 Ly255283 98+% 50mg $608 2021-12-16 Buy
Ambeed A646553 Ly255283 98+% 100mg $796 2021-12-16 Buy
Ambeed A646553 Ly255283 98+% 250mg $1193 2021-12-16 Buy
Ambeed A646553 Ly255283 98+% 1g $2984 2021-12-16 Buy
American Custom Chemicals Corporation API0008308 LY-255283 95.00% 1MG $215.25 2021-12-16 Buy
American Custom Chemicals Corporation API0008308 LY-255283 95.00% 5MG $658.12 2021-12-16 Buy
American Custom Chemicals Corporation API0008308 LY-255283 95.00% 25MG $791.93 2021-12-16 Buy
ApexBio Technology B6978 LY255283 10mg $282 2021-12-16 Buy
ApexBio Technology B6978 LY255283 50mg $1190 2021-12-16 Buy
Cayman Chemical 70715 LY255283 ≥98% 1mg $25 2024-03-01 Buy
Cayman Chemical 70715 LY255283 ≥98% 5mg $94 2024-03-01 Buy
Cayman Chemical 70715 LY255283 ≥98% 10mg $140 2024-03-01 Buy

Properties

Melting point :160-162 °C
Boiling point :573.4±60.0 °C(Predicted)
Density :1.157±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMSO: >20mg/mL
form :powder
pka :5.11±0.10(Predicted)
color :off-white to light yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Antagonists of the chemotactic and inflammatory lipoxygenase product leukotriene B4 (LTB4) have been potential drug development targets for several years. The tetrazole LY255283 is a competitive antagonist of the BLT2 receptor. It displaces radiolabeled LTB4 from guinea pig lung membrane, with an IC50 of about 100 nM. LY255283 exhibits IC50 values of ~950 nM and >10 μM at human recombinant BLT2 and BLT1 receptors, respectively. LY255283 inhibits eosinophil chemotaxis by 80% at a concentration of 10 μM, and inhibits the binding of radiolabeled LTB4 to eosinophil membranes with an IC50 of 260 nM.

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