DIACYLGLYCEROL KINASE INHIBITOR II
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- $32 - $800
- Product name: DIACYLGLYCEROL KINASE INHIBITOR II
- CAS: 120166-69-0
- MF: C28H25F2N3OS
- MW: 489.58
- EINECS:
- MDL Number:MFCD00069258
- Synonyms:DIACYLGLYCEROL KINASE INHIBITOR I (R59 949);DIACYLGLYCEROL KINASE INHIBITOR II;R59949, 3-[2-[4-(bis(4-Fluorophenyl)methylene)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone;3-[2-[4-Bis(4-fluorophenyl)methylenepiperidino]ethyl]-2,3-dihydro-2-thioxoquinazolin-4(1H)-one;3-[2-[4-(bis(4-Fluorophenyl)Methylene)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone, R59949;DAG Kinase Inhibitor II;DAG Kinase Inhibitor;3-[2-(4-[BIS(4-FLUOROPHENYL)-METHYLENE)-1-PIPERIDINYL)ETHYL]-2,3-DIHYDRO-2-THIOXO-4[1H]-QUINAZOLINONE
16 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
Package
- 1MG
- 2mg
- 5MG
- 10mg
- 25mg
- ManufacturerAK Scientific
- Product number8726BA
- Product descriptionDiacylglycerol Kinase Inhibitor II
- Packaging25mg
- Price$522
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000211
- Product descriptionR-59949 95.00%
- Packaging1MG
- Price$590.01
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000211
- Product descriptionR-59949 95.00%
- Packaging5MG
- Price$707.67
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB102452
- Product description3-[2-[4-[Bis(4-Fluorophenyl)Methylene]-1-Piperidinyl]Ethyl]-2,3-Dihydro-2-Thioxo-4(1H)-Quinazolinone
- Packaging1mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB102452
- Product description3-[2-[4-[Bis(4-Fluorophenyl)Methylene]-1-Piperidinyl]Ethyl]-2,3-Dihydro-2-Thioxo-4(1H)-Quinazolinone
- Packaging2mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB102452
- Product description3-[2-[4-[Bis(4-Fluorophenyl)Methylene]-1-Piperidinyl]Ethyl]-2,3-Dihydro-2-Thioxo-4(1H)-Quinazolinone
- Packaging5mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB102452
- Product description3-[2-[4-[Bis(4-Fluorophenyl)Methylene]-1-Piperidinyl]Ethyl]-2,3-Dihydro-2-Thioxo-4(1H)-Quinazolinone
- Packaging10mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB102452
- Product description3-[2-[4-[Bis(4-Fluorophenyl)Methylene]-1-Piperidinyl]Ethyl]-2,3-Dihydro-2-Thioxo-4(1H)-Quinazolinone
- Packaging25mg
- Price$800
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21221
- Product descriptionR-59-949 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21221
- Product descriptionR-59-949 ≥98%
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21221
- Product descriptionR-59-949 ≥98%
- Packaging10mg
- Price$214
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21221
- Product descriptionR-59-949 ≥98%
- Packaging25mg
- Price$381
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0028440
- Product descriptionR59949 ≥99.0%
- Packaging5mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberD5794
- Product descriptionDiacylglycerol Kinase Inhibitor II solid
- Packaging1mg
- Price$36.18
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number266788
- Product descriptionDiacylglycerol Kinase Inhibitor II
- Packaging5mg
- Price$172
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberD5794
- Product descriptionDiacylglycerol Kinase Inhibitor II solid
- Packaging5mg
- Price$173
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8726BA | Diacylglycerol Kinase Inhibitor II | 25mg | $522 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000211 | R-59949 95.00% | 1MG | $590.01 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000211 | R-59949 95.00% | 5MG | $707.67 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB102452 | 3-[2-[4-[Bis(4-Fluorophenyl)Methylene]-1-Piperidinyl]Ethyl]-2,3-Dihydro-2-Thioxo-4(1H)-Quinazolinone | 1mg | $100 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB102452 | 3-[2-[4-[Bis(4-Fluorophenyl)Methylene]-1-Piperidinyl]Ethyl]-2,3-Dihydro-2-Thioxo-4(1H)-Quinazolinone | 2mg | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB102452 | 3-[2-[4-[Bis(4-Fluorophenyl)Methylene]-1-Piperidinyl]Ethyl]-2,3-Dihydro-2-Thioxo-4(1H)-Quinazolinone | 5mg | $240 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB102452 | 3-[2-[4-[Bis(4-Fluorophenyl)Methylene]-1-Piperidinyl]Ethyl]-2,3-Dihydro-2-Thioxo-4(1H)-Quinazolinone | 10mg | $400 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB102452 | 3-[2-[4-[Bis(4-Fluorophenyl)Methylene]-1-Piperidinyl]Ethyl]-2,3-Dihydro-2-Thioxo-4(1H)-Quinazolinone | 25mg | $800 | 2021-12-16 | Buy |
| Cayman Chemical | 21221 | R-59-949 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 21221 | R-59-949 ≥98% | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 21221 | R-59-949 ≥98% | 10mg | $214 | 2024-03-01 | Buy |
| Cayman Chemical | 21221 | R-59-949 ≥98% | 25mg | $381 | 2024-03-01 | Buy |
| ChemScene | CS-0028440 | R59949 ≥99.0% | 5mg | $270 | 2021-12-16 | Buy |
| Sigma-Aldrich | D5794 | Diacylglycerol Kinase Inhibitor II solid | 1mg | $36.18 | 2024-03-01 | Buy |
| Sigma-Aldrich | 266788 | Diacylglycerol Kinase Inhibitor II | 5mg | $172 | 2024-03-01 | Buy |
| Sigma-Aldrich | D5794 | Diacylglycerol Kinase Inhibitor II solid | 5mg | $173 | 2024-03-01 | Buy |
Properties
Melting point :228-230 °C
Boiling point :637.1±65.0 °C(Predicted)
Density :1.36±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :0.1 M HCl: slightly soluble
form :solid
pka :11.24±0.20(Predicted)
color :pale yellow
Boiling point :637.1±65.0 °C(Predicted)
Density :1.36±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :0.1 M HCl: slightly soluble
form :solid
pka :11.24±0.20(Predicted)
color :pale yellow
Safety Information
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Description
DAG Kinase Inhibitor is an inhibitor of DGK (Diacylglycerol kinase; DAG Kinase) and is useful for elucidating the roles of protein kinase C (PKC). DAG Kinase Inhibitor has also been reported to inhibit DGK in several systems such as isolated platelet membranes, whole platelets and ghost erythrocytes. Additional reports have shown to inhibit in a concentration dependent manner. DAG Kinase Inhibitor may also inhibit other pathways such as NADPH and potentially interfere with the lipid-mediated assembly process of oxidase components as reported using a cell-free system. This particular isoform, R59949, has been reported to potentially exhibit selective inhibition of DGK-α.More related product prices
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