2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
![2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one price.](/CAS/GIF/1234480-50-2.gif)
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- $32 - $2097.8
- Product name: 2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
- CAS: 1234480-50-2
- MF: C26H30N6O3
- MW: 474.55
- EINECS:
- MDL Number:MFCD18782742
- Synonyms:2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one;2-((2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl)amino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one;2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one XMD 8-92;XMD 8-92 2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one;2-[2-ethoxy-4-(4-hydroxypiperidin-1-yl)anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one;XMD 8-92 trifluoroacetate;2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4;XMD 8-92
25 prices
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Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Axon Medchem
- Biorbyt Ltd
- BroadPharm
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
Package
- 1mg
- 2MG
- 10
- 0.5mg
- 50
- 5MG
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1000mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001566
- Product descriptionXMD8-92 95.00%
- Packaging2MG
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001566
- Product descriptionXMD8-92 95.00%
- Packaging5MG
- Price$503.48
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3943
- Product descriptionXMD8-92
- Packaging100mg
- Price$460
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0197
- Product descriptionXMD8-92
- Packaging1mg
- Price$73
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0197
- Product descriptionXMD8-92
- Packaging5mg
- Price$116
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0197
- Product descriptionXMD8-92
- Packaging10mg
- Price$153
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60410
- Product descriptionXMD8-92 ≥98%
- Packaging20mg
- Price$428
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1846
- Product descriptionXMD8-92 99%
- Packaging5mg
- Price$104.5
- Updated2021-12-16
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- ManufacturerBiorbyt Ltd
- Product numberorb181349
- Product descriptionXMD8-92 >98%
- Packaging100mg
- Price$542.3
- Updated2021-12-16
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- ManufacturerBiorbyt Ltd
- Product numberorb181349
- Product descriptionXMD8-92 >98%
- Packaging250mg
- Price$1060.8
- Updated2021-12-16
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- ManufacturerBiorbyt Ltd
- Product numberorb181349
- Product descriptionXMD8-92 >98%
- Packaging1000mg
- Price$2097.8
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-25377
- Product descriptionXMD8-92
- Packaging50mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19173
- Product descriptionXMD8-92 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19173
- Product descriptionXMD8-92 ≥98%
- Packaging5mg
- Price$90
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19173
- Product descriptionXMD8-92 ≥98%
- Packaging10mg
- Price$117
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19173
- Product descriptionXMD8-92 ≥98%
- Packaging25mg
- Price$267
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | INB0001566 | XMD8-92 95.00% | 2MG | $220 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001566 | XMD8-92 95.00% | 5MG | $503.48 | 2021-12-16 | Buy |
| ApexBio Technology | A3943 | XMD8-92 | 100mg | $460 | 2021-12-16 | Buy |
| Apolloscientific | BISN0197 | XMD8-92 | 1mg | $73 | 2021-12-16 | Buy |
| Apolloscientific | BISN0197 | XMD8-92 | 5mg | $116 | 2021-12-16 | Buy |
| Apolloscientific | BISN0197 | XMD8-92 | 10mg | $153 | 2021-12-16 | Buy |
| Arctom | CFN60410 | XMD8-92 ≥98% | 20mg | $428 | 2021-12-16 | Buy |
| Axon Medchem | Axon1846 | XMD8-92 99% | 5mg | $104.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181349 | XMD8-92 >98% | 100mg | $542.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181349 | XMD8-92 >98% | 250mg | $1060.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181349 | XMD8-92 >98% | 1000mg | $2097.8 | 2021-12-16 | Buy |
| BroadPharm | BP-25377 | XMD8-92 | 50mg | $450 | 2021-12-16 | Buy |
| Cayman Chemical | 19173 | XMD8-92 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 19173 | XMD8-92 ≥98% | 5mg | $90 | 2024-03-01 | Buy |
| Cayman Chemical | 19173 | XMD8-92 ≥98% | 10mg | $117 | 2024-03-01 | Buy |
| Cayman Chemical | 19173 | XMD8-92 ≥98% | 25mg | $267 | 2024-03-01 | Buy |
Properties
Boiling point :741.8±70.0 °C(Predicted)
Density :1.301
storage temp. :Store at 4°C
solubility :≥23.75 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :14.76±0.20(Predicted)
color :Off-white to light yellow
Density :1.301
storage temp. :Store at 4°C
solubility :≥23.75 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :14.76±0.20(Predicted)
color :Off-white to light yellow
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
XMD8-92 is an ERK5 inhibitor (Kd = 80 nM) that less potently inhibits DCAMKL2, TNK1, and Plk4 (Kds = 190, 890, and 600 nM, respectively), from a panel of 402 different tested kinases. It blocks ERK5 autophosphorylation, ERK5-mediated phosphorylation of promyelocytic leukemia protein (PML), and PML-dependent activation of p21. XMD8-92 suppresses tumor cell proliferation in vitro and tumor growth and angiogenesis in vivo. XMD8-92 inhibits AP-1 transcriptional activity induced by MEK5-activated ERK5 but not that induced by Cdc37.More related product prices
BEZ235 (NVP-BEZ235, Dactolisib) LY 294002 HYDROCHLORIDE Sunitinib Malate 871700-17-3 BIX 02189 Y27632 (hydrochloride) XMD16-5 XMD17 109 ACK1-B19 3-Hydroxypiperidine 4-Hydroxypiperidine 3-METHOXYPIPERIDINE 6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-Related product price
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Suppliers and manufacturers
career henan chemical co
![2-[2-ethoxy-4-(4-hydroxypiperidin-1-yl)anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one](https://img.chemicalbook.com/ProductImageEN/2020-1/small/22947d81-53c7-4525-9e91-03a8efda556e.png)
ATK CHEMICAL COMPANY LIMITED
Hubei Jusheng Technology Co.,Ltd.
CONIER CHEM AND PHARMA LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
TargetMol Chemicals Inc.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
$1.00 /1KG
2-[2-ethoxy-4-(4-hydroxypiperidin-1-yl)anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one CAS:1234480-50-2
2-[2-ethoxy-4-(4-hydroxypiperidin-1-yl)anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one CAS:1234480-50-2