(1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide
![(1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide price.](/CAS/20150408/GIF/1246303-14-9.gif)
|
- $40 - $805
- Product name: (1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide
- CAS: 1246303-14-9
- MF: C25H29BrN4O2
- MW: 497.43
- EINECS:
- MDL Number:MFCD22416858
- Synonyms:(1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide;VU0359595;(1R,2R)-N-([S]-1-{4-[5-BROMO-2-OXO-2,3-DIHYDRO-1H-BENZO(D)IMIDAZOL-1-YL]PIPERIDIN-1-YL}PROPAN-2-YL)-2-PHENYLCYCLOPROPANECARBOXAMIDE;VU0359595;(1R,2R)-N-[(2S)-1-[4-(5-bromo-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]-2-phenylcyclopropane-1-carboxamide;Cyclopropanecarboxamide, N-[(1S)-2-[4-(5-bromo-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-1-methylethyl]-2-phenyl-, (1R,2R)-;ML270
11 prices
Selected condition：
Brand
- ApexBio Technology
- Cayman Chemical
- Medical Isotopes, Inc.
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- ManufacturerApexBio Technology
- Product numberC3919
- Product descriptionVU0359595
- Packaging5mg
- Price$111
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3919
- Product descriptionVU0359595
- Packaging10mg
- Price$201
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3919
- Product descriptionVU0359595
- Packaging25mg
- Price$452
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10955
- Product descriptionVU0359595 ≥95%
- Packaging1mg
- Price$40
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10955
- Product descriptionVU0359595 ≥95%
- Packaging5mg
- Price$139
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10955
- Product descriptionVU0359595 ≥95%
- Packaging10mg
- Price$236
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10955
- Product descriptionVU0359595 ≥95%
- Packaging25mg
- Price$541
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number73007
- Product descriptionVU0359595
- Packaging25mg
- Price$805
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberV787565
- Product descriptionVU0359595
- Packaging1mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberV787565
- Product descriptionVU0359595
- Packaging5mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberV787565
- Product descriptionVU0359595
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ApexBio Technology | C3919 | VU0359595 | 5mg | $111 | 2021-12-16 | Buy |
| ApexBio Technology | C3919 | VU0359595 | 10mg | $201 | 2021-12-16 | Buy |
| ApexBio Technology | C3919 | VU0359595 | 25mg | $452 | 2021-12-16 | Buy |
| Cayman Chemical | 10955 | VU0359595 ≥95% | 1mg | $40 | 2024-03-01 | Buy |
| Cayman Chemical | 10955 | VU0359595 ≥95% | 5mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 10955 | VU0359595 ≥95% | 10mg | $236 | 2024-03-01 | Buy |
| Cayman Chemical | 10955 | VU0359595 ≥95% | 25mg | $541 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | 73007 | VU0359595 | 25mg | $805 | 2021-12-16 | Buy |
| TRC | V787565 | VU0359595 | 1mg | $50 | 2021-12-16 | Buy |
| TRC | V787565 | VU0359595 | 5mg | $85 | 2021-12-16 | Buy |
| TRC | V787565 | VU0359595 | 10mg | $150 | 2021-12-16 | Buy |
Properties
Density :1.395±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear
pka :11.11±0.30(Predicted)
form :powder
color :white to beige
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear
pka :11.11±0.30(Predicted)
form :powder
color :white to beige
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Phospholipase D (PLD) is an enzyme that cleaves the head group from phospholipids, producing the second messenger phosphatidic acid. Two mammalian isoforms of PLD, PLD1, and PLD2, have been identified, with multiple splice variants of each. Although the two isoforms share structural and functional features, they are regulated differently and apparently subserve distinct roles. VU0359595 is an inhibitor of PLD1 (IC50 = 3.7 nM) that is >1,700-fold selective over PLD2 (IC50 = 6.4 μM). Preliminary evidence suggests that VU0359595 does not interact with the catalytic site of PLD, but instead may bind and inhibit PLD through an allosteric site.More related product prices
N[2-(4-Oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]quinoline-3-carboxamide Hydrochloride VU 0285683 VU 0364439 VU 0360223 VU 0357121 VU 0365114 VU 0360172 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine 5-Amino-3,4-dimethyl-thieno[2,3-c]pyridazine-6-carboxylic acid 4-trifluoromethanesulfonyl-benzylamide 1160247-92-6 1161205-04-4 VU0483605 VU 591 hydrochloride 893990-34-6 VU-29 VU 0364770 409351-28-6 VU 0357017 hydrochloride VU 0409106 333415-38-6Related product price
- N[2-(4-Oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]quinoline-3-carboxamide Hydrochloride
$195-675 - VU 0285683
$130-2230 - VU 0364439
$32-2395.3