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ChemicalBook >> CAS DataBase List >> (R)-(-)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate

(R)-(-)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate

(R)-(-)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate price.
  • $28 - $2880
  • Product name: (R)-(-)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
  • CAS: 1268524-71-5
  • MF: C23H25ClN4O2S
  • MW: 456.99
  • EINECS:
  • MDL Number:MFCD22124456
  • Synonyms:(R)-(-)-JQ1 Enantiomer;(R)-(-)-JQ1;(R)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno-[3,2-f][1,2,4]triazolo[4,3-a][1;(R)-(-)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate;(-)-JQ-1;(R)-(-)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4];JQ-1;JQ1;-JQ1;JQ 1;(6R)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester
Price27 Properties Safety Information Description
27 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
Package
  • 2mg
  • 5mg
  • 10
  • 1mg
  • 1unit
  • 25mg
  • 250mg
  • 1g
  • 10mM(in 1mL DMSO)
  • 10mg
  • 50mg
  • 100mg
  • 25 mg
  • ManufacturerAK Scientific
  • Product number2826AH
  • Product descriptiontert-Butyl2-((6R)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
  • Packaging5mg
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8181
  • Product description(-)-JQ1
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8181
  • Product description(-)-JQ1
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8181
  • Product description(-)-JQ1
  • Packaging10mM(in 1mL DMSO)
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8181
  • Product description(-)-JQ1
  • Packaging25mg
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8181
  • Product description(-)-JQ1
  • Packaging50mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8181
  • Product description(-)-JQ1
  • Packaging100mg
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11232
  • Product description(-)-JQ1 ≥98%
  • Packaging1mg
  • Price$28
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11232
  • Product description(-)-JQ1 ≥98%
  • Packaging5mg
  • Price$98
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11232
  • Product description(-)-JQ1 ≥98%
  • Packaging10mg
  • Price$140
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11232
  • Product description(−)-JQ1 ≥98%
  • Packaging25 mg
  • Price$245
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0646
  • Product description(R)-(-)-JQ1Enantiomer 99.66%
  • Packaging2mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0646
  • Product description(R)-(-)-JQ1Enantiomer 99.66%
  • Packaging5mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0646
  • Product description(R)-(-)-JQ1Enantiomer 99.66%
  • Packaging10mg
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0646
  • Product description(R)-(-)-JQ1Enantiomer 99.66%
  • Packaging50mg
  • Price$864
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0646
  • Product description(R)-(-)-JQ1Enantiomer 99.66%
  • Packaging100mg
  • Price$1440
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2826AH tert-Butyl2-((6R)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 5mg $230 2021-12-16 Buy
ApexBio Technology A8181 (-)-JQ1 1unit $28 2021-12-16 Buy
ApexBio Technology A8181 (-)-JQ1 5mg $120 2021-12-16 Buy
ApexBio Technology A8181 (-)-JQ1 10mM(in 1mL DMSO) $200 2021-12-16 Buy
ApexBio Technology A8181 (-)-JQ1 25mg $380 2021-12-16 Buy
ApexBio Technology A8181 (-)-JQ1 50mg $700 2021-12-16 Buy
ApexBio Technology A8181 (-)-JQ1 100mg $1000 2021-12-16 Buy
Cayman Chemical 11232 (-)-JQ1 ≥98% 1mg $28 2024-03-01 Buy
Cayman Chemical 11232 (-)-JQ1 ≥98% 5mg $98 2024-03-01 Buy
Cayman Chemical 11232 (-)-JQ1 ≥98% 10mg $140 2024-03-01 Buy
Cayman Chemical 11232 (−)-JQ1 ≥98% 25 mg $245 2024-03-01 Buy
ChemScene CS-0646 (R)-(-)-JQ1Enantiomer 99.66% 2mg $77 2021-12-16 Buy
ChemScene CS-0646 (R)-(-)-JQ1Enantiomer 99.66% 5mg $144 2021-12-16 Buy
ChemScene CS-0646 (R)-(-)-JQ1Enantiomer 99.66% 10mg $252 2021-12-16 Buy
ChemScene CS-0646 (R)-(-)-JQ1Enantiomer 99.66% 50mg $864 2021-12-16 Buy
ChemScene CS-0646 (R)-(-)-JQ1Enantiomer 99.66% 100mg $1440 2021-12-16 Buy
Next Last

Properties

Boiling point :610.4±65.0 °C(Predicted)
Density :1.33
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :2.05±0.60(Predicted)
form :powder
color :white to beige
InChIKey :DNVXATUJJDPFDM-QGZVFWFLSA-N

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. (±)-JQ1 displaces BET proteins from chromatin by competitively binding to the acetyl-lysine recognition pocket of BET bromodomains. The (?)-JQ1 stereoisomer has no appreciable affinity to BET bromodomains, whereas enantiomerically pure (+)-JQ1 binds to BRD4 bromodomains 1 and 2 with Kd values of ~50 and 90 nM, respectively.

More related product prices

6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-triMethyl-, (6S)- 1268524-70-4

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Suppliers and manufacturers

career henan chemical co
(R)-(-)-JQ1 Enantiomer
$1.00 /1KG
(R)-(-)-JQ1 Enantiomer CAS:1268524-71-5
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