5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
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- $40 - $764.03
- Product name: 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
- CAS: 1434-54-4
- MF: C22H31NO2
- MW: 341.49
- EINECS:
- MDL Number:MFCD00079212
- Synonyms:5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE;5-pregnen-3B-ol-20-one-16A-carbonitrile;(3S,8S,9S,10R,13S,14S,16R,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile;(3S,8S,9S,10R,13S,14S,16R,17S)-17-ethanoyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile;pregnenolone-16α-carbonitrile;16α-Cyano-3β-hydroxypregn-5-en-20-one;U-14975;16-alpha)-3-hydroxy-20-oxopregn-5-ene-16-carbonitrile(3-bet
14 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Sigma-Aldrich
- TRC
Package
- 25mg
- 50MG
- 100MG
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number1342CA
- Product descriptionPregnenolonecarbonitrile
- Packaging250mg
- Price$326
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0012880
- Product description5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE 95.00%
- Packaging50MG
- Price$609.04
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0012880
- Product description5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE 95.00%
- Packaging100MG
- Price$664.22
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0012880
- Product description5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE 95.00%
- Packaging250MG
- Price$764.03
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3884
- Product descriptionPregnenoloneCarbonitrile
- Packaging50mg
- Price$56
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3884
- Product descriptionPregnenoloneCarbonitrile
- Packaging100mg
- Price$106
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16343
- Product descriptionPregnenolone Carbonitrile ≥98%
- Packaging25mg
- Price$40
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16343
- Product descriptionPregnenolone Carbonitrile ≥98%
- Packaging50mg
- Price$64
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16343
- Product descriptionPregnenolone Carbonitrile ≥98%
- Packaging100mg
- Price$111
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16343
- Product descriptionPregnenolone Carbonitrile ≥98%
- Packaging250mg
- Price$218
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberP0543
- Product description5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97%
- Packaging50mg
- Price$83.5
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberP0543
- Product description5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97%
- Packaging100mg
- Price$150
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberP0543
- Product description5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97%
- Packaging250mg
- Price$290
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberP712240
- Product descriptionPregnenoloneCarbonitrile
- Packaging1g
- Price$605
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 1342CA | Pregnenolonecarbonitrile | 250mg | $326 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0012880 | 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE 95.00% | 50MG | $609.04 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0012880 | 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE 95.00% | 100MG | $664.22 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0012880 | 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE 95.00% | 250MG | $764.03 | 2021-12-16 | Buy |
ApexBio Technology | C3884 | PregnenoloneCarbonitrile | 50mg | $56 | 2021-12-16 | Buy |
ApexBio Technology | C3884 | PregnenoloneCarbonitrile | 100mg | $106 | 2021-12-16 | Buy |
Cayman Chemical | 16343 | Pregnenolone Carbonitrile ≥98% | 25mg | $40 | 2024-03-01 | Buy |
Cayman Chemical | 16343 | Pregnenolone Carbonitrile ≥98% | 50mg | $64 | 2024-03-01 | Buy |
Cayman Chemical | 16343 | Pregnenolone Carbonitrile ≥98% | 100mg | $111 | 2024-03-01 | Buy |
Cayman Chemical | 16343 | Pregnenolone Carbonitrile ≥98% | 250mg | $218 | 2024-03-01 | Buy |
Sigma-Aldrich | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 50mg | $83.5 | 2024-03-01 | Buy |
Sigma-Aldrich | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 100mg | $150 | 2024-03-01 | Buy |
Sigma-Aldrich | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 250mg | $290 | 2024-03-01 | Buy |
TRC | P712240 | PregnenoloneCarbonitrile | 1g | $605 | 2021-12-16 | Buy |
Properties
Melting point :225-228 °C(Solv: methanol (67-56-1); benzene (71-43-2))
Boiling point :508.5±50.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
Flash point :93 °C
storage temp. :2-8°C
solubility :Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
form :White to off-white solid.
pka :14.95±0.70(Predicted)
color :White to off-white
EPA Substance Registry System :Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3.beta.,16.alpha.)- (1434-54-4)
Boiling point :508.5±50.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
Flash point :93 °C
storage temp. :2-8°C
solubility :Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
form :White to off-white solid.
pka :14.95±0.70(Predicted)
color :White to off-white
EPA Substance Registry System :Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3.beta.,16.alpha.)- (1434-54-4)
Safety Information
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Description
Pregnenolone carbonitrile (PCN) is a catatoxic steroid that acts as an agonist of the rodent pregnane X receptor (PXR) at μM concentrations. It has been shown to mediate induction of hepatic cytochrome P450 3A, organic anion transporting peptide-2, and cholesterol 7α-hydroxylase, regulating both xenobiotic and bile acid homeostasis by enhancing hepatic uptake and biliary excretion. Activation of PXR by 50 mg/kg PCN administered to obesity-prone AKR/J mice has been reported to attenuate the development of high-fat diet-induced obesity and insulin resistance.Related product price
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