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ChemicalBook >> CAS DataBase List >> 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE

5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE

5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE price.
  • $40 - $764.03
  • Product name: 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
  • CAS: 1434-54-4
  • MF: C22H31NO2
  • MW: 341.49
  • EINECS:
  • MDL Number:MFCD00079212
  • Synonyms:5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE;5-pregnen-3B-ol-20-one-16A-carbonitrile;(3S,8S,9S,10R,13S,14S,16R,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile;(3S,8S,9S,10R,13S,14S,16R,17S)-17-ethanoyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile;pregnenolone-16α-carbonitrile;16α-Cyano-3β-hydroxypregn-5-en-20-one;U-14975;16-alpha)-3-hydroxy-20-oxopregn-5-ene-16-carbonitrile(3-bet
Price14 Properties Safety Information Description
14 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
Package
  • 25mg
  • 50MG
  • 100MG
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number1342CA
  • Product descriptionPregnenolonecarbonitrile
  • Packaging250mg
  • Price$326
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0012880
  • Product description5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE 95.00%
  • Packaging50MG
  • Price$609.04
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0012880
  • Product description5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE 95.00%
  • Packaging100MG
  • Price$664.22
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0012880
  • Product description5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE 95.00%
  • Packaging250MG
  • Price$764.03
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3884
  • Product descriptionPregnenoloneCarbonitrile
  • Packaging50mg
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3884
  • Product descriptionPregnenoloneCarbonitrile
  • Packaging100mg
  • Price$106
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16343
  • Product descriptionPregnenolone Carbonitrile ≥98%
  • Packaging25mg
  • Price$40
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16343
  • Product descriptionPregnenolone Carbonitrile ≥98%
  • Packaging50mg
  • Price$64
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16343
  • Product descriptionPregnenolone Carbonitrile ≥98%
  • Packaging100mg
  • Price$111
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16343
  • Product descriptionPregnenolone Carbonitrile ≥98%
  • Packaging250mg
  • Price$218
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP0543
  • Product description5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97%
  • Packaging50mg
  • Price$83.5
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP0543
  • Product description5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97%
  • Packaging100mg
  • Price$150
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP0543
  • Product description5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97%
  • Packaging250mg
  • Price$290
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberP712240
  • Product descriptionPregnenoloneCarbonitrile
  • Packaging1g
  • Price$605
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1342CA Pregnenolonecarbonitrile 250mg $326 2021-12-16 Buy
American Custom Chemicals Corporation CHM0012880 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE 95.00% 50MG $609.04 2021-12-16 Buy
American Custom Chemicals Corporation CHM0012880 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE 95.00% 100MG $664.22 2021-12-16 Buy
American Custom Chemicals Corporation CHM0012880 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE 95.00% 250MG $764.03 2021-12-16 Buy
ApexBio Technology C3884 PregnenoloneCarbonitrile 50mg $56 2021-12-16 Buy
ApexBio Technology C3884 PregnenoloneCarbonitrile 100mg $106 2021-12-16 Buy
Cayman Chemical 16343 Pregnenolone Carbonitrile ≥98% 25mg $40 2024-03-01 Buy
Cayman Chemical 16343 Pregnenolone Carbonitrile ≥98% 50mg $64 2024-03-01 Buy
Cayman Chemical 16343 Pregnenolone Carbonitrile ≥98% 100mg $111 2024-03-01 Buy
Cayman Chemical 16343 Pregnenolone Carbonitrile ≥98% 250mg $218 2024-03-01 Buy
Sigma-Aldrich P0543 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% 50mg $83.5 2024-03-01 Buy
Sigma-Aldrich P0543 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% 100mg $150 2024-03-01 Buy
Sigma-Aldrich P0543 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% 250mg $290 2024-03-01 Buy
TRC P712240 PregnenoloneCarbonitrile 1g $605 2021-12-16 Buy

Properties

Melting point :225-228 °C(Solv: methanol (67-56-1); benzene (71-43-2))
Boiling point :508.5±50.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
Flash point :93 °C
storage temp. :2-8°C
solubility :Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
form :White to off-white solid.
pka :14.95±0.70(Predicted)
color :White to off-white
EPA Substance Registry System :Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3.beta.,16.alpha.)- (1434-54-4)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Pregnenolone carbonitrile (PCN) is a catatoxic steroid that acts as an agonist of the rodent pregnane X receptor (PXR) at μM concentrations. It has been shown to mediate induction of hepatic cytochrome P450 3A, organic anion transporting peptide-2, and cholesterol 7α-hydroxylase, regulating both xenobiotic and bile acid homeostasis by enhancing hepatic uptake and biliary excretion. Activation of PXR by 50 mg/kg PCN administered to obesity-prone AKR/J mice has been reported to attenuate the development of high-fat diet-induced obesity and insulin resistance.

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Suppliers and manufacturers

ATK CHEMICAL COMPANY LIMITED
Aladdin Scientific Shanghai Macklin Biochemical Co.,Ltd. Sigma-Aldrich Shanghai EFE Biological Technology Co., Ltd. Lynnchem Novachemistry ChemeGen(Shanghai) Biotechnology Co.,Ltd. Shanghai Puluokai Medical Technology Co., LTD MedBioPharmaceutical Technology Inc