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ChemicalBook >> CAS DataBase List >> cyclo(L-leucyl-L-tryptophyl)

cyclo(L-leucyl-L-tryptophyl)

cyclo(L-leucyl-L-tryptophyl) price.
  • $91 - $949.56
  • Product name: cyclo(L-leucyl-L-tryptophyl)
  • CAS: 15136-34-2
  • MF: C17H21N3O2
  • MW: 299.37
  • EINECS:
  • MDL Number:
  • Synonyms:cyclo(L-leucyl-L-tryptophyl);Cyclo(L-Leu-L-Trp);Cyclo(Trp-Leu);(3S,6S)-3-(1H-indol-3-ylmethyl)-6-(2-methylpropyl)piperazine-2,5-dione;cyclo-L-Trp-L-Leu;2,5-Piperazinedione, 3-(1H-indol-3-ylmethyl)-6-(2-methylpropyl)-, (3S,6S)-
9 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
Package
  • 5mg
  • 25mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 2g
  • ManufacturerAK Scientific
  • Product number6775CJ
  • Product descriptionCyclo(L-leucyl-L-tryptophyl)
  • Packaging5mg
  • Price$368
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPEP0011679
  • Product descriptionCYCLO(-L-LEU-L-TRP) 95.00%
  • Packaging5MG
  • Price$496.14
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC108311
  • Product descriptionCyclo(-Leu-Trp)
  • Packaging100mg
  • Price$91
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC108311
  • Product descriptionCyclo(-Leu-Trp)
  • Packaging250mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC108311
  • Product descriptionCyclo(-Leu-Trp)
  • Packaging500mg
  • Price$315
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC108311
  • Product descriptionCyclo(-Leu-Trp)
  • Packaging1g
  • Price$546
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC108311
  • Product descriptionCyclo(-Leu-Trp)
  • Packaging2g
  • Price$949.56
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number24942
  • Product descriptionCyclo(L-Leu-L-Trp) ≥95%
  • Packaging5mg
  • Price$242
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24942
  • Product descriptionCyclo(L-Leu-L-Trp) ≥95%
  • Packaging25mg
  • Price$846
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6775CJ Cyclo(L-leucyl-L-tryptophyl) 5mg $368 2021-12-16 Buy
American Custom Chemicals Corporation PEP0011679 CYCLO(-L-LEU-L-TRP) 95.00% 5MG $496.14 2021-12-16 Buy
Biosynth Carbosynth FC108311 Cyclo(-Leu-Trp) 100mg $91 2021-12-16 Buy
Biosynth Carbosynth FC108311 Cyclo(-Leu-Trp) 250mg $180 2021-12-16 Buy
Biosynth Carbosynth FC108311 Cyclo(-Leu-Trp) 500mg $315 2021-12-16 Buy
Biosynth Carbosynth FC108311 Cyclo(-Leu-Trp) 1g $546 2021-12-16 Buy
Biosynth Carbosynth FC108311 Cyclo(-Leu-Trp) 2g $949.56 2021-12-16 Buy
Cayman Chemical 24942 Cyclo(L-Leu-L-Trp) ≥95% 5mg $242 2024-03-01 Buy
Cayman Chemical 24942 Cyclo(L-Leu-L-Trp) ≥95% 25mg $846 2024-03-01 Buy

Properties

Boiling point :635.2±45.0 °C(Predicted)
Density :1.182±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Methanol: Soluble
form :A solid
pka :13.21±0.60(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Cyclo(L-Leu-L-Trp) is a diketopiperazine metabolite originally isolated from Penicillium.1 It is active against various bacteria (MICs = 125-1000 μg/ml) and fungi (MICs = 8-64 μg/ml), and it inhibits the production rate of hydroxy radicals in an electron spin resonance (ESR) spectroscopy-based assay (IC50 = 1.8 μM).2,3 Cyclo(L-Leu-L-Trp) is a bitter tastant that can rapidly permeate rat taste cell membranes ex vivo when used at a concentration of 1 mM.4 It also acts as a melatonin receptor agonist in X. laevis melanophores, inhibiting cAMP accumulation when used at a concentration of 20 μM, an effect that is blocked by the melatonin receptor antagonist luzindole .5

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