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ChemicalBook >> CAS DataBase List >> 15(S)-Latanoprost

15(S)-Latanoprost

15(S)-Latanoprost price.
  • $77 - $11550
  • Product name: 15(S)-Latanoprost
  • CAS: 145773-22-4
  • MF: C26H40O5
  • MW: 432.59
  • EINECS:687-773-3
  • MDL Number:MFCD04974500
  • Synonyms:15(S)-LATANOPROST;15(S)-LATANOPROST ISOPROPYL ESTER;15-EPI LATANOPROST ISOPROPYL ESTER;9ALPHA,11ALPHA,15S-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROST-5Z-EN-1-OIC ACID ISOPROPYL ESTER;(5Z,9ALPHA,11ALPHA,15S)-9,11,15-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROST-5Z-EN-1-OATE ISOPROPYL ESTER;(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoic acid isopropyl ester;15-epi Latanoprost;Latanoprost Related Compound B (25 mg) (Isopropyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoate)
12 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • AvaChem
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10MG
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product numberY7554
  • Product description(Z)-Isopropyl7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-enyl)cyclopentyl)hept-5-enoate
  • Packaging50mg
  • Price$995
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007851
  • Product description15(S)-LATANOPROST 95.00%
  • Packaging10MG
  • Price$11550
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2029
  • Product description15(S)-Latanoprost
  • Packaging5mg
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2029
  • Product description15(S)-Latanoprost
  • Packaging10mg
  • Price$890
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2029
  • Product description15(S)-Latanoprost
  • Packaging100mg
  • Price$2200
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16818
  • Product description15(S)-Latanoprost ≥98%
  • Packaging1mg
  • Price$77
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16818
  • Product description15(S)-Latanoprost ≥98%
  • Packaging5mg
  • Price$345
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16818
  • Product description15(S)-Latanoprost ≥98%
  • Packaging10mg
  • Price$612
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16818
  • Product description15(S)-Latanoprost ≥98%
  • Packaging50mg
  • Price$1530
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPHR3022
  • Product descriptionLatanoprost Related Compound B pharmaceutical secondary standard, certified reference material
  • Packaging50MG
  • Price$634
  • Updated2024-03-01
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  • ManufacturerSigma-Aldrich
  • Product number1357497
  • Product descriptionLatanoprost Related Compound B
  • Packaging25mg
  • Price$1850
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberL177285
  • Product description(15S)-Latanoprost
  • Packaging5mg
  • Price$250
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y7554 (Z)-Isopropyl7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-enyl)cyclopentyl)hept-5-enoate 50mg $995 2021-12-16 Buy
American Custom Chemicals Corporation API0007851 15(S)-LATANOPROST 95.00% 10MG $11550 2021-12-16 Buy
AvaChem 2029 15(S)-Latanoprost 5mg $490 2021-12-16 Buy
AvaChem 2029 15(S)-Latanoprost 10mg $890 2021-12-16 Buy
AvaChem 2029 15(S)-Latanoprost 100mg $2200 2021-12-16 Buy
Cayman Chemical 16818 15(S)-Latanoprost ≥98% 1mg $77 2024-03-01 Buy
Cayman Chemical 16818 15(S)-Latanoprost ≥98% 5mg $345 2024-03-01 Buy
Cayman Chemical 16818 15(S)-Latanoprost ≥98% 10mg $612 2024-03-01 Buy
Cayman Chemical 16818 15(S)-Latanoprost ≥98% 50mg $1530 2024-03-01 Buy
Sigma-Aldrich PHR3022 Latanoprost Related Compound B pharmaceutical secondary standard, certified reference material 50MG $634 2024-03-01 Buy
Sigma-Aldrich 1357497 Latanoprost Related Compound B 25mg $1850 2024-03-01 Buy
TRC L177285 (15S)-Latanoprost 5mg $250 2021-12-16 Buy

Properties

Boiling point :583.8±50.0 °C(Predicted)
Density :1.093±0.06 g/cm3(Predicted)
Flash point :-16 °C
storage temp. :−20°C
solubility :DMF: 100 mg/ml; DMSO: 100 mg/ml; DMSO:PBS (1:12): 80 μg/ml; Ethanol: 100 mg/ml
form :Oil
pka :14.84±0.70(Predicted)
color :Colourless
InChIKey :GGXICVAJURFBLW-SCTZCWPJSA-N

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P281 Use personal protective equipment as required.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 μg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys. 15(S)-Latanoprost is a potential impurity in most commercial preparations of the latanoprost bulk drug product.

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