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ChemicalBook >> CAS DataBase List >> 4,5-DIAMINOFLUORESCEIN DIACETATE

4,5-DIAMINOFLUORESCEIN DIACETATE

4,5-DIAMINOFLUORESCEIN DIACETATE price.
  • $56 - $2100
  • Product name: 4,5-DIAMINOFLUORESCEIN DIACETATE
  • CAS: 205391-02-2
  • MF: C24H18N2O7
  • MW: 446.41
  • EINECS:
  • MDL Number:MFCD05865101
  • Synonyms:4,5-DIAMINOFLUORESCEIN DIACETATE;4,5-DIAMINOFLUORORESCEIN DIACETATE;5,6-DIAMINOFLUORESCEIN DIACETATE;2-(3,6-DIACETYLOXY-9H-XANTHEN-9-YL)-4,5-DIAMINO-BENZOIC ACID;DAF-2 DA;DAF-2 DA, CELL PERMEABLE;DAF-2 DIACETATE;5,6-Diaminofluorescein diacetat
12 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
Package
  • 251505-1MG
  • 100μg
  • 250μg
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-D0085-M005
  • Product descriptionDAF-2 DA ≥98%(HPLC)
  • Packaging5mg
  • Price$988
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1697AH
  • Product descriptionDAF-2 DA
  • Packaging1mg
  • Price$553
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberFRL0000189
  • Product description5,6-DIAMINOFLUORESCEIN DIACETATE 95.00%
  • Packaging5MG
  • Price$502.61
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number85165
  • Product descriptionDAF-2 diacetate ≥95%
  • Packaging100μg
  • Price$56
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number85165
  • Product descriptionDAF-2 diacetate ≥95%
  • Packaging250μg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number85165
  • Product descriptionDAF-2 diacetate ≥95%
  • Packaging500μg
  • Price$229
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number85165
  • Product descriptionDAF-2 diacetate ≥95%
  • Packaging1mg
  • Price$429
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number50277
  • Product description5,6-Diaminofluorescein diacetate BioReagent, suitable for fluorescence, 98% (HPCE)
  • Packaging1MG
  • Price$581
  • Updated2022-05-15
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number251505-M
  • Product descriptionDAF-2 DA - CAS 205391-02-2 - Calbiochem A cell-permeable derivative of DAF-2 that is hydrolyzed to DAF-2 by intracellular esterases.
  • Packaging251505-1MG
  • Price$586
  • Updated2023-06-20
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number251505-M
  • Product descriptionDAF-2 DA - CAS 205391-02-2 - Calbiochem A cell-permeable derivative of DAF-2 that is hydrolyzed to DAF-2 by intracellular esterases.
  • Packaging1mg
  • Price$621
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD2813
  • Product description4,5-Diaminofluorescein diacetate ≥98% (HPLC)
  • Packaging1mg
  • Price$801
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberD193320
  • Product descriptionDAF-2 DA
  • Packaging10mg
  • Price$2100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-D0085-M005 DAF-2 DA ≥98%(HPLC) 5mg $988 2021-12-16 Buy
AK Scientific 1697AH DAF-2 DA 1mg $553 2021-12-16 Buy
American Custom Chemicals Corporation FRL0000189 5,6-DIAMINOFLUORESCEIN DIACETATE 95.00% 5MG $502.61 2021-12-16 Buy
Cayman Chemical 85165 DAF-2 diacetate ≥95% 100μg $56 2024-03-01 Buy
Cayman Chemical 85165 DAF-2 diacetate ≥95% 250μg $121 2024-03-01 Buy
Cayman Chemical 85165 DAF-2 diacetate ≥95% 500μg $229 2024-03-01 Buy
Cayman Chemical 85165 DAF-2 diacetate ≥95% 1mg $429 2024-03-01 Buy
Sigma-Aldrich 50277 5,6-Diaminofluorescein diacetate BioReagent, suitable for fluorescence, 98% (HPCE) 1MG $581 2022-05-15 Buy
Sigma-Aldrich 251505-M DAF-2 DA - CAS 205391-02-2 - Calbiochem A cell-permeable derivative of DAF-2 that is hydrolyzed to DAF-2 by intracellular esterases. 251505-1MG $586 2023-06-20 Buy
Sigma-Aldrich 251505-M DAF-2 DA - CAS 205391-02-2 - Calbiochem A cell-permeable derivative of DAF-2 that is hydrolyzed to DAF-2 by intracellular esterases. 1mg $621 2024-03-01 Buy
Sigma-Aldrich D2813 4,5-Diaminofluorescein diacetate ≥98% (HPLC) 1mg $801 2024-03-01 Buy
TRC D193320 DAF-2 DA 10mg $2100 2021-12-16 Buy

Properties

Boiling point :719.0±60.0 °C(Predicted)
Density :1.54±0.1 g/cm3(Predicted)
Flash point :87 °C
storage temp. :2-8°C
solubility :DMSO: <2mg/mL
form :Pale yellow solution
pka :2.92±0.20(Predicted)
color :white

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H371 May cause damage to organs Specific target organ toxicity, single exposure Category 2 Warning P260, P264, P270, P309+P311, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

DAF-2 diacetate is a sensitive fluorescent indicator for the detection and bioimaging of nitric oxide (NO). It is a cell-permeable derivative of DAF-2. Upon entry into the cell, DAF-2 diacetate is transformed into the less cell-permeable DAF-2 by cellular esterases thus preventing loss of signal due to diffusion of the molecule from the cell. In the presence of oxygen, DAF-2 reacts with NO to yield the highly fluorescent triazolofluorescein (DAF-2T). Fluorescence is monitored using excitation and emission wavelengths of 485 and 538 nm, respectively. At neutral pH the detection limit for NO is 2-5 nM. DAF-2 diacetate can be utilized in cells which produce small amounts of NO, such as endothelial cells, as well as in cells which generate large amount of NO, such as macrophages.

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