1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone
![1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone price.](/CAS/GIF/314245-33-5.gif)
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- $38 - $2839
- Product name: 1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone
- CAS: 314245-33-5
- MF: C18H21FN2O
- MW: 300.37
- EINECS:
- MDL Number:MFCD01917473
- Synonyms:1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone;IU1;1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE;IU1;1-(1-(4-fluorophenyl)-2,5-diMethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethanone;Ethanone, 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-;IU-1 (USP14 inhibitor IU1);IU1; IU-1; IU 1;CS-1901
32 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 5MG
- 25mg
- 10mg
- 10mM(in 1mL DMSO)
- 50mg
- 100mg
- 200mg
- 250mg
- 1G
- 2.5G
- 5G
- ManufacturerAK Scientific
- Product numberSYN5673
- Product descriptionIU1
- Packaging10mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5673
- Product descriptionIU1
- Packaging100mg
- Price$1174
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001404
- Product description1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%
- Packaging5MG
- Price$401.06
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001404
- Product description1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%
- Packaging1G
- Price$613
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001404
- Product description1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%
- Packaging2.5G
- Price$818
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001404
- Product description1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00%
- Packaging5G
- Price$1018
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4002
- Product descriptionIU1
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4002
- Product descriptionIU1
- Packaging10mM(in 1mL DMSO)
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4002
- Product descriptionIU1
- Packaging50mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4002
- Product descriptionIU1
- Packaging100mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611936
- Product descriptionIU1 >98%
- Packaging100mg
- Price$838.1
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611936
- Product descriptionIU1 >98%
- Packaging250mg
- Price$1431.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611936
- Product descriptionIU1 >98%
- Packaging1g
- Price$2839
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10617
- Product descriptionIU1 ≥98%
- Packaging5mg
- Price$38
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10617
- Product descriptionIU1 ≥98%
- Packaging10mg
- Price$71
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10617
- Product descriptionIU1 ≥98%
- Packaging50mg
- Price$292
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5673 | IU1 | 10mg | $198 | 2021-12-16 | Buy |
| AK Scientific | SYN5673 | IU1 | 100mg | $1174 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001404 | 1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00% | 5MG | $401.06 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001404 | 1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00% | 1G | $613 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001404 | 1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00% | 2.5G | $818 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001404 | 1-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2-(1-PYRROLIDINYL)ETHANONE 95.00% | 5G | $1018 | 2021-12-16 | Buy |
| ApexBio Technology | A4002 | IU1 | 10mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A4002 | IU1 | 10mM(in 1mL DMSO) | $60 | 2021-12-16 | Buy |
| ApexBio Technology | A4002 | IU1 | 50mg | $200 | 2021-12-16 | Buy |
| ApexBio Technology | A4002 | IU1 | 100mg | $360 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611936 | IU1 >98% | 100mg | $838.1 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611936 | IU1 >98% | 250mg | $1431.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611936 | IU1 >98% | 1g | $2839 | 2021-12-16 | Buy |
| Cayman Chemical | 10617 | IU1 ≥98% | 5mg | $38 | 2024-03-01 | Buy |
| Cayman Chemical | 10617 | IU1 ≥98% | 10mg | $71 | 2024-03-01 | Buy |
| Cayman Chemical | 10617 | IU1 ≥98% | 50mg | $292 | 2024-03-01 | Buy |
Properties
Boiling point :437.0±45.0 °C(Predicted)
Density :1.16±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :8.20±0.20(Predicted)
form :powder
color :off-white to light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Density :1.16±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :8.20±0.20(Predicted)
form :powder
color :off-white to light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Polybiquitinylation designates proteins for proteasomal degradation. USP14 is one of several deubiquitinating enzymes (DUBs) responsible for shortening proteasome-bound ubiquitin chains, which is known to antagonize the degradation of ubiquitin-protein conjugates. IU1 is a reversible, small molecule inhibitor of deubiquitination by USP14 that demonstrates an IC50 value of 4-5 μM. IU1 selectively stimulates ubiquitin-dependent protein degradation in vitro at 34 μM and in MEF cells at 50 μM. At 75 μM, IU1 reduces accumulation of oxidized proteins in HEK293 cells, alleviating cytotoxicity induced by oxidative stress.More related product prices
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Suppliers and manufacturers
career henan chemical co
![1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone](https://img.chemicalbook.com/ProductImageEN/2019-7/small/c91c41ae-094d-41fd-a776-cae3f48b22a3.jpg)
Shanghai Daken Advanced Materials Co.,Ltd
ATK CHEMICAL COMPANY LIMITED
Hubei Jusheng Technology Co.,Ltd.
Chongqing Chemdad Co., Ltd
Dideu Industries Group Limited
InvivoChem
TargetMol Chemicals Inc.
Aladdin Scientific
3B Pharmachem (Wuhan) International Co.,Ltd.
$7.00 /1KG
1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone CAS:314245-33-5
1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone CAS:314245-33-5