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ChemicalBook >> CAS DataBase List >> 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide

2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide

2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)-
isoquinolinylidene)acetaMide price.
  • $49 - $775
  • Product name: 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide
  • CAS: 331001-62-8
  • MF: C21H22N4O2
  • MW: 362.42
  • EINECS:
  • MDL Number:MFCD00354369
  • Synonyms:AcetaMide, 2-[2-(4-acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-diMethyl-1(2H)-isoquinolinylidene)-;2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide;2-[2-(4-Acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-diMethyl-1(2H)-isoquinolinylidene)-acetaMide;IQ 1; IQ1;2-[(4-Acetylphenyl)hydrazinylidene]-2-(3,3-dimethyl-4H-isoquinolin-1-yl)acetamide;IQ-1 - CAS 331001-62-8 - Calbiochem;spontaneous differentiation,expansion,β-catenin/p300,β-catenin/CBP,inhibit,P19 cells,Wnt,Inhibitor,PR72/130,IQ 1,ESCs;2-((4-Acetylphenyl)diazenyl)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)acetamide
20 prices
Selected condition:
Brand
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerApexBio Technology
  • Product numberB7700
  • Product descriptionIQ1
  • Packaging5mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7700
  • Product descriptionIQ1
  • Packaging10mg
  • Price$123
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7700
  • Product descriptionIQ1
  • Packaging25mg
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7700
  • Product descriptionIQ1
  • Packaging50mg
  • Price$362
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16153
  • Product descriptionIQ-1 ≥98%
  • Packaging5mg
  • Price$106
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16153
  • Product descriptionIQ-1 ≥98%
  • Packaging10mg
  • Price$178
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16153
  • Product descriptionIQ-1 ≥98%
  • Packaging25mg
  • Price$414
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16153
  • Product descriptionIQ-1 ≥98%
  • Packaging50mg
  • Price$775
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5721
  • Product descriptionIQ1 99.49%
  • Packaging5mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5721
  • Product descriptionIQ1 99.49%
  • Packaging10mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5721
  • Product descriptionIQ1 99.49%
  • Packaging25mg
  • Price$216
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5721
  • Product descriptionIQ1 99.49%
  • Packaging50mg
  • Price$312
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002215
  • Product descriptionIQ1 98+%
  • Packaging5mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002215
  • Product descriptionIQ1 98+%
  • Packaging10mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9952
  • Product descriptionIQ-1 >98%
  • Packaging100mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number46884
  • Product descriptionIQ1
  • Packaging10mg
  • Price$640
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B7700 IQ1 5mg $95 2021-12-16 Buy
ApexBio Technology B7700 IQ1 10mg $123 2021-12-16 Buy
ApexBio Technology B7700 IQ1 25mg $252 2021-12-16 Buy
ApexBio Technology B7700 IQ1 50mg $362 2021-12-16 Buy
Cayman Chemical 16153 IQ-1 ≥98% 5mg $106 2024-03-01 Buy
Cayman Chemical 16153 IQ-1 ≥98% 10mg $178 2024-03-01 Buy
Cayman Chemical 16153 IQ-1 ≥98% 25mg $414 2024-03-01 Buy
Cayman Chemical 16153 IQ-1 ≥98% 50mg $775 2024-03-01 Buy
ChemScene CS-5721 IQ1 99.49% 5mg $72 2021-12-16 Buy
ChemScene CS-5721 IQ1 99.49% 10mg $96 2021-12-16 Buy
ChemScene CS-5721 IQ1 99.49% 25mg $216 2021-12-16 Buy
ChemScene CS-5721 IQ1 99.49% 50mg $312 2021-12-16 Buy
Crysdot CD31002215 IQ1 98+% 5mg $49 2021-12-16 Buy
Crysdot CD31002215 IQ1 98+% 10mg $80 2021-12-16 Buy
DC Chemicals DC9952 IQ-1 >98% 100mg $300 2021-12-16 Buy
Medical Isotopes, Inc. 46884 IQ1 10mg $640 2021-12-16 Buy

Properties

Boiling point :591.2±50.0 °C(Predicted)
Density :1.23±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 10 mg/ml
form :powder
pka :15.71±0.50(Predicted)
color :yellow to orange

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

IQ-1 is a cell-permeable tetrahydroisoquinolinylidene compound that maintains long-term mouse embryonic stem cell (ESC) pluripotency. When used at 4 μg/ml with Wnt3a, it allows ESCs to form embryoid bodies that continue to express markers of pluripotency, including α-fetoprotein and β-III tubulin. IQ-1 blocks the interaction of the protein Naked cuticle with a subunit of the protein phosphatase PP2A, altering signaling through Wnt/β-catenin and maintaining the expression of stem cell markers Oct4, Nanog, and Rex1 in ESCs.

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