4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide

$39 - $931
Product name: 4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide
CAS: 420092-79-1
MF: C16H11ClN2O5S
MW: 378.79
EINECS:
MDL Number:
Synonyms:4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide;SW155246;Benzenesulfonamide, 4-chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-;SW155246 >=98% (HPLC);4-chloro-N-(4-hydroxynaphthalen- 1-yl)-3-nitrobenzenesulfonamide;SW 155246,cancer,hDNMT1,DNMTs,DNMT1 inhibitor,SW155246,Inhibitor,SW-155246,inhibit,mDNMT3A,DNA MTases,DNA Methyltransferase

Price8 Properties Safety Information Description

8 prices

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Brand

AK Scientific
Cayman Chemical
Sigma-Aldrich

Package

1mg
5mg
10mg
25mg
50mg
100mg

ManufacturerAK Scientific
Product numberSYN5477
Product descriptionSW155246
Packaging50mg
Price$547
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberSYN5477
Product descriptionSW155246
Packaging100mg
Price$931
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number21865
Product descriptionSW155246 ≥98%
Packaging1mg
Price$39
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number21865
Product descriptionSW155246 ≥98%
Packaging5mg
Price$106
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number21865
Product descriptionSW155246 ≥98%
Packaging10mg
Price$172
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number21865
Product descriptionSW155246 ≥98%
Packaging25mg
Price$378
Updated2024-03-01
Buy

ManufacturerSigma-Aldrich
Product numberSML1136
Product descriptionSW155246 ≥98% (HPLC)
Packaging5mg
Price$105
Updated2022-05-15
Buy

ManufacturerSigma-Aldrich
Product numberSML1136
Product descriptionSW155246 ≥98% (HPLC)
Packaging25mg
Price$423
Updated2022-05-15
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	SYN5477	SW155246	50mg	$547	2021-12-16	Buy
AK Scientific	SYN5477	SW155246	100mg	$931	2021-12-16	Buy
Cayman Chemical	21865	SW155246 ≥98%	1mg	$39	2024-03-01	Buy
Cayman Chemical	21865	SW155246 ≥98%	5mg	$106	2024-03-01	Buy
Cayman Chemical	21865	SW155246 ≥98%	10mg	$172	2024-03-01	Buy
Cayman Chemical	21865	SW155246 ≥98%	25mg	$378	2024-03-01	Buy
Sigma-Aldrich	SML1136	SW155246 ≥98% (HPLC)	5mg	$105	2022-05-15	Buy
Sigma-Aldrich	SML1136	SW155246 ≥98% (HPLC)	25mg	$423	2022-05-15	Buy

Properties

storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
color :white to light brown

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning		P264, P280, P305+P351+P338,P337+P313P

Precautionary statements:

P305+P351+P338

IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SW155246 is an inhibitor of DNA methyltransferase 1 (DNMT1; IC₅₀ = 1.2 μM). It is selective for human DNMT1 over murine DNMT3 (IC₅₀ = 38 μM). SW155246 inhibits HeLa and A549 tumor cell growth in a redox-independent manner (IC₅₀s = 8-20 μM). It also inhibits genomic methylation in HeLa cells when used at concentrations ranging from 10 to 18.6 μM.

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