3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide
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- $73 - $1169
- Product name: 3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide
- CAS: 420831-40-9
- MF: C19H21BrN2O3S
- MW: 437.35
- EINECS:
- MDL Number:MFCD03140195
- Synonyms:N-(3-Bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]-benzamide;SIRT2 Inhibitor,AK-7;N-(3-Bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]-benzamide SIRT2 Inhibitor,AK-7;AK 7, >=98%;3-(azepan-1-ylsulfonyl)-N-(3-broMophenyl)benzaMide;AK-7;Benzamide, N-(3-bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]-;AK-7;AK7;AK 7
31 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 25mg
- 50
- 5mg
- 10mg
- 50mg
- 100mg
- 250mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3511-M005
- Product descriptionAK-7 ≥98%(NMR)
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY1898
- Product description3-(1-azepanylsulfonyl)-N-(3-bromophenyl)benzamide
- Packaging10mg
- Price$192
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY1898
- Product description3-(1-azepanylsulfonyl)-N-(3-bromophenyl)benzamide
- Packaging250mg
- Price$1169
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA566314
- Product descriptionAK-7 98+%
- Packaging50mg
- Price$373
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA566314
- Product descriptionAK-7 98+%
- Packaging25mg
- Price$287
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA566314
- Product descriptionAK-7 98+%
- Packaging10mg
- Price$169
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4713
- Product descriptionAK-7
- Packaging10mg
- Price$173
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4713
- Product descriptionAK-7
- Packaging50mg
- Price$551
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4713
- Product descriptionAK-7
- Packaging100mg
- Price$945
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2270
- Product descriptionAK7 100%
- Packaging10mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545902
- Product descriptionAK-7 >98%
- Packaging5mg
- Price$154.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545902
- Product descriptionAK-7 >98%
- Packaging25mg
- Price$365.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181357
- Product descriptionSIRT2 Inhibitor II, AK-7 >98%
- Packaging250mg
- Price$1133.9
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14004
- Product descriptionAK-7 ≥95%
- Packaging5mg
- Price$73
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14004
- Product descriptionAK-7 ≥95%
- Packaging10mg
- Price$138
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14004
- Product descriptionAK-7 ≥95%
- Packaging25mg
- Price$324
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3511-M005 | AK-7 ≥98%(NMR) | 5mg | $80 | 2021-12-16 | Buy |
| AK Scientific | Y1898 | 3-(1-azepanylsulfonyl)-N-(3-bromophenyl)benzamide | 10mg | $192 | 2021-12-16 | Buy |
| AK Scientific | Y1898 | 3-(1-azepanylsulfonyl)-N-(3-bromophenyl)benzamide | 250mg | $1169 | 2021-12-16 | Buy |
| Ambeed | A566314 | AK-7 98+% | 50mg | $373 | 2021-12-16 | Buy |
| Ambeed | A566314 | AK-7 98+% | 25mg | $287 | 2021-12-16 | Buy |
| Ambeed | A566314 | AK-7 98+% | 10mg | $169 | 2021-12-16 | Buy |
| ApexBio Technology | B4713 | AK-7 | 10mg | $173 | 2021-12-16 | Buy |
| ApexBio Technology | B4713 | AK-7 | 50mg | $551 | 2021-12-16 | Buy |
| ApexBio Technology | B4713 | AK-7 | 100mg | $945 | 2021-12-16 | Buy |
| Axon Medchem | Axon2270 | AK7 100% | 10mg | $99 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545902 | AK-7 >98% | 5mg | $154.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545902 | AK-7 >98% | 25mg | $365.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181357 | SIRT2 Inhibitor II, AK-7 >98% | 250mg | $1133.9 | 2021-12-16 | Buy |
| Cayman Chemical | 14004 | AK-7 ≥95% | 5mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 14004 | AK-7 ≥95% | 10mg | $138 | 2024-03-01 | Buy |
| Cayman Chemical | 14004 | AK-7 ≥95% | 25mg | $324 | 2024-03-01 | Buy |
Properties
Density :1.469±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: ≥15mg/mL
form :powder
pka :12.28±0.70(Predicted)
color :white to tan
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: ≥15mg/mL
form :powder
pka :12.28±0.70(Predicted)
color :white to tan
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
The sirtuin SIRT2 is a deacetylase which targets α-tubulin, histone 4, forkhead transcription factors, and several other substrates. It has roles in metabolic diseases, cancer, age-related disorders, and neurodegenerative diseases, potentially including Alzheimer’s, Huntington’s, and Parkinson’s diseases. AK-7 is a cell- and brain-permeable inhibitor of SIRT2 (IC50 = 15.5 μM). In culture, it dimishes neuronal cell death induced by mutant huntingtin fragment. In addition, AK-7 down-regulates cholesterol biosynthetic gene expression and reduces total cholesterol levels in neurons in vivo.More related product prices
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