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ChemicalBook >> CAS DataBase List >> 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide

2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide

2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide price.
  • $32 - $1190
  • Product name: 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide
  • CAS: 442633-00-3
  • MF: C18H17FN2O
  • MW: 296.34
  • EINECS:
  • MDL Number:MFCD03036271
  • Synonyms:2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide;CK 666;CK-0944666;Arp2/3 Complex Inhibitor I, CK-666 ;CK 666 (CK 0944666);Benzamide, 2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]-;Inhibitor,HIV,meshwork,CK-666,Actin-related protein 2/3 complex,allosteric,CK 666,state,effector,active,inhibit,CK666,trabecular,Human immunodeficiency virus,Arp2/3 Complex
20 prices
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  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 1mg
  • 2MG
  • 5mg
  • 10mg
  • 25mg
  • 10
  • 50mg
  • ManufacturerAK Scientific
  • Product number8437BA
  • Product description2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide
  • Packaging5mg
  • Price$193
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8437BA
  • Product description2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide
  • Packaging10mg
  • Price$268
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0000847
  • Product descriptionCK 666 95.00%
  • Packaging2MG
  • Price$168
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0000847
  • Product descriptionCK 666 95.00%
  • Packaging5MG
  • Price$499.03
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5500
  • Product descriptionCK666
  • Packaging50mg
  • Price$1190
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546174
  • Product descriptionCK-666 >98%
  • Packaging5mg
  • Price$181.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546174
  • Product descriptionCK-666 >98%
  • Packaging25mg
  • Price$455.6
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29038
  • Product descriptionCK-666
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29038
  • Product descriptionCK-666
  • Packaging5mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29038
  • Product descriptionCK-666
  • Packaging10mg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0012973
  • Product descriptionCK-666 99.63%
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0012973
  • Product descriptionCK-666 99.63%
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0012973
  • Product descriptionCK-666 99.63%
  • Packaging50mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0006
  • Product descriptionCK-666 ≥98% (HPLC), powder
  • Packaging5mg
  • Price$132
  • Updated2024-03-01
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  • ManufacturerSigma-Aldrich
  • Product number182515
  • Product descriptionArp2/3 Complex Inhibitor I, CK-666
  • Packaging25mg
  • Price$225
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0006
  • Product descriptionCK-666 ≥98% (HPLC), powder
  • Packaging25mg
  • Price$516
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8437BA 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide 5mg $193 2021-12-16 Buy
AK Scientific 8437BA 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide 10mg $268 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000847 CK 666 95.00% 2MG $168 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000847 CK 666 95.00% 5MG $499.03 2021-12-16 Buy
ApexBio Technology B5500 CK666 50mg $1190 2021-12-16 Buy
Biorbyt Ltd orb546174 CK-666 >98% 5mg $181.9 2021-12-16 Buy
Biorbyt Ltd orb546174 CK-666 >98% 25mg $455.6 2021-12-16 Buy
Cayman Chemical 29038 CK-666 1mg $32 2024-03-01 Buy
Cayman Chemical 29038 CK-666 5mg $86 2024-03-01 Buy
Cayman Chemical 29038 CK-666 10mg $153 2024-03-01 Buy
ChemScene CS-0012973 CK-666 99.63% 5mg $90 2021-12-16 Buy
ChemScene CS-0012973 CK-666 99.63% 10mg $160 2021-12-16 Buy
ChemScene CS-0012973 CK-666 99.63% 50mg $650 2021-12-16 Buy
Sigma-Aldrich SML0006 CK-666 ≥98% (HPLC), powder 5mg $132 2024-03-01 Buy
Sigma-Aldrich 182515 Arp2/3 Complex Inhibitor I, CK-666 25mg $225 2024-03-01 Buy
Sigma-Aldrich SML0006 CK-666 ≥98% (HPLC), powder 25mg $516 2024-03-01 Buy

Properties

Boiling point :528.2±50.0 °C(Predicted)
Density :1.235±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥25mg/mL
pka :13.86±0.46(Predicted)
form :powder
color :white to tan
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CK-666 (442633-00-3) is a potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC50?= 4 μM for human ARP2/3.1?Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the cell spreading process.2 CK-666 attenuates BBB dysfunction induced by methamphetamine.3?It is an important new tool for studying actin assembly and the diverse range of actin-related processes in normal4 and pathophysiology5.

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