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ChemicalBook >> CAS DataBase List >> Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid

Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid

Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid price.
  • $14 - $3213.79
  • Product name: Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
  • CAS: 486460-00-8
  • MF: C15H18F3NO4
  • MW: 333.31
  • EINECS:691-120-8
  • MDL Number:MFCD06659147
  • Synonyms:Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,(bR)-;(R)-Sitagliptin N-Boc-Acid IMpurity;Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid (3R)-N-(tert-Butoxycarbonyl)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid;Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid, >=99%;(3R)-N-Boc-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid;(3R)-N-(tert-Butoxycarbonyl)-3-aMino-4-(2,4,5-trifluorophenyl)-butanoic acid- Boc-(R)-3-AMino-4-(2,4,5-trifluorophenyl) butanoic acid (BOC acid);[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-(R)-benzenebuta;BOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID
Price23 Properties Safety Information Description
23 prices
Selected condition：
Brand
  • Acrotein
  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Chemenu
  • ChemScene
  • Crysdot
  • Matrix Scientific
  • TRC
Package
  • 1G
  • 5g
  • 10g
  • 25g
  • 50g
  • 100g
  • 250g
  • 500g
  • 1000g
  • ManufacturerAcrotein
  • Product numberA-1307
  • Product descriptionN-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%
  • Packaging5g
  • Price$32.82
  • Updated2021-12-16
  • Buy
  • ManufacturerAcrotein
  • Product numberA-1307
  • Product descriptionN-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%
  • Packaging25g
  • Price$107.25
  • Updated2021-12-16
  • Buy
  • ManufacturerAcrotein
  • Product numberA-1307
  • Product descriptionN-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%
  • Packaging100g
  • Price$321.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX1035
  • Product descriptionBoc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacid
  • Packaging25g
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number486460008
  • Product descriptionBoc-(R)-3-AMino-4-(2,4,5-trifluorophenyl)butanoicacid
  • Packaging25g
  • Price$218.25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA240774
  • Product description(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoicacid 98%
  • Packaging5g
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA240774
  • Product description(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoicacid 98%
  • Packaging500g
  • Price$727
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0027721
  • Product description(3R)-N-(TERT-BUTOXYCARBONYL)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID 95.00%
  • Packaging1G
  • Price$1212.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0027721
  • Product description(3R)-N-(TERT-BUTOXYCARBONYL)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID 95.00%
  • Packaging5G
  • Price$3213.79
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB29150
  • Product descriptionBoc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
  • Packaging10g
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB29150
  • Product descriptionBoc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
  • Packaging25g
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB29150
  • Product descriptionBoc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
  • Packaging50g
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB29150
  • Product descriptionBoc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
  • Packaging100g
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB29150
  • Product descriptionBoc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
  • Packaging250g
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM220713
  • Product description(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoicacid 95+%
  • Packaging1000g
  • Price$912
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-M3237
  • Product description(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoicacid
  • Packaging10g
  • Price$50
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Acrotein A-1307 N-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97% 5g $32.82 2021-12-16 Buy
Acrotein A-1307 N-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97% 25g $107.25 2021-12-16 Buy
Acrotein A-1307 N-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97% 100g $321.75 2021-12-16 Buy
AK Scientific X1035 Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacid 25g $147 2021-12-16 Buy
Alichem 486460008 Boc-(R)-3-AMino-4-(2,4,5-trifluorophenyl)butanoicacid 25g $218.25 2021-12-16 Buy
Ambeed A240774 (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoicacid 98% 5g $14 2021-12-16 Buy
Ambeed A240774 (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoicacid 98% 500g $727 2021-12-16 Buy
American Custom Chemicals Corporation HCH0027721 (3R)-N-(TERT-BUTOXYCARBONYL)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID 95.00% 1G $1212.75 2021-12-16 Buy
American Custom Chemicals Corporation HCH0027721 (3R)-N-(TERT-BUTOXYCARBONYL)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID 95.00% 5G $3213.79 2021-12-16 Buy
Biosynth Carbosynth FB29150 Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid 10g $40 2021-12-16 Buy
Biosynth Carbosynth FB29150 Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid 25g $60 2021-12-16 Buy
Biosynth Carbosynth FB29150 Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid 50g $110 2021-12-16 Buy
Biosynth Carbosynth FB29150 Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid 100g $200 2021-12-16 Buy
Biosynth Carbosynth FB29150 Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid 250g $400 2021-12-16 Buy
Chemenu CM220713 (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoicacid 95+% 1000g $912 2021-12-16 Buy
ChemScene CS-M3237 (3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoicacid 10g $50 2021-12-16 Buy
Next Last

Properties

Melting point :136-138℃
Boiling point :443.1±45.0 °C(Predicted)
Density :1.292±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form :Solid
pka :4.30±0.10(Predicted)
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Boc-(R) -3-amino-4 -(2,4, 5-trifluorophenyl) butyric acid is an important intermediate for the preparation of sitagliptin. Sitagliptinphosphate is the first dipeptidase -IV(dpp-4) inhibitor approved by FDA in 2006. It is used for the treatment of type II diabetes mellitus. It has obvious hypoglycemic effect when used alone or in combination with metformin and pioglitazone, and it is safe to take, well tolerated, with few adverse reactions.

More related product prices

ETHYLENE OXIDE Butyraldehyde Sebacic acid 2-Deoxy-L-ribose BOC-(R)-3-AMINO-4-(2-FLUORO-PHENYL)-BUTYRIC ACID BOC-(R)-3-AMINO-4-(3,4-DIFLUORO-PHENYL)-BUTYRIC ACID BOC-(R)-3-AMINO-4-(4-FLUORO-PHENYL)-BUTYRIC ACID 3-OXO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID METHYL ESTER Sitagliptin 243139-71-1 2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate 5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione 762240-92-6 762240-99-3 Sitagliptin Defuoro IMpurity 3 2,3,5-TRIFLUOROPHENYLACETIC ACID

Related product price

Suppliers and manufacturers

Hebei Mojin Biotechnology Co., Ltd
BOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID
$0.00 /25KG
BOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID CAS:486460-00-8
Hebei Guanlang Biotechnology Co,.LTD
Saxagliptin Intermediate
$10.70 /1kg
Saxagliptin Intermediate CAS:486460-00-8
Sinoway Industrial co., ltd.
Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
$0.00 /1kg
Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid CAS:486460-00-8
Hangzhou ICH Biofarm Co., Ltd
(3R)-N-(tert-butoxycarbonyl)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid
$0.00 /1kg
(3R)-N-(tert-butoxycarbonyl)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid CAS:486460-00-8
Allfluoro pharmaceutical co. ltd.
Capot Chemical Co.,Ltd.
Shanghai Daken Advanced Materials Co.,Ltd
Beijing Cooperate Pharmaceutical Co.,Ltd
Hi-Tech Chemistry Corp
Henan Tianfu Chemical Co.,Ltd.