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ChemicalBook >> CAS DataBase List >> 4Hydroxy Tamoxifen

4Hydroxy Tamoxifen

4Hydroxy Tamoxifen price.
  • $166 - $2194.5
  • Product name: 4Hydroxy Tamoxifen
  • CAS: 82413-23-8
  • MF: C26H29NO2
  • MW: 387.51
  • EINECS:
  • MDL Number:
  • Synonyms:4-[(1Z)-1-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]phenol;4'-Hydroxy TaMoxifen (contains up to 10% E isoMer);Phenol, 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-;Tamoxifen Citrate Impurity 13 (4'-Hydroxytamoxifen);4’-hydroxy Tamoxifen
8 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 2.5MG
  • 5mg
  • 25MG
  • ManufacturerAK Scientific
  • Product number8798CN
  • Product description4'-Hydroxytamoxifen
  • Packaging5mg
  • Price$668
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberMTB0001871
  • Product description4'-HYDROXY TAMOXIFEN 95.00%
  • Packaging2.5MG
  • Price$742.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberMTB0001871
  • Product description4'-HYDROXY TAMOXIFEN 95.00%
  • Packaging25MG
  • Price$2194.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4624
  • Product description4’-hydroxyTamoxifen
  • Packaging1mg
  • Price$187
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4624
  • Product description4’-hydroxyTamoxifen
  • Packaging5mg
  • Price$584
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19519
  • Product description4’-hydroxy Tamoxifen ≥98% (may contain up to 10% of the (E) isomer)
  • Packaging1mg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19519
  • Product description4’-hydroxy Tamoxifen ≥98% (may contain up to 10% of the (E) isomer)
  • Packaging5mg
  • Price$513
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberH954730
  • Product description4’-HydroxyTamoxifen(containsupto10%Eisomer)
  • Packaging25mg
  • Price$1695
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8798CN 4'-Hydroxytamoxifen 5mg $668 2021-12-16 Buy
American Custom Chemicals Corporation MTB0001871 4'-HYDROXY TAMOXIFEN 95.00% 2.5MG $742.5 2021-12-16 Buy
American Custom Chemicals Corporation MTB0001871 4'-HYDROXY TAMOXIFEN 95.00% 25MG $2194.5 2021-12-16 Buy
ApexBio Technology C4624 4’-hydroxyTamoxifen 1mg $187 2021-12-16 Buy
ApexBio Technology C4624 4’-hydroxyTamoxifen 5mg $584 2021-12-16 Buy
Cayman Chemical 19519 4’-hydroxy Tamoxifen ≥98% (may contain up to 10% of the (E) isomer) 1mg $166 2024-03-01 Buy
Cayman Chemical 19519 4’-hydroxy Tamoxifen ≥98% (may contain up to 10% of the (E) isomer) 5mg $513 2024-03-01 Buy
TRC H954730 4’-HydroxyTamoxifen(containsupto10%Eisomer) 25mg $1695 2021-12-16 Buy

Properties

Melting point :150-153°C
Boiling point :514.4±50.0 °C(Predicted)
Density :1.092±0.06 g/cm3(Predicted)
storage temp. :Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility :Chloroform (Slightly), Dichloromethane, Methanol (Slightly)
form :Solid
pka :10.32±0.15(Predicted)
color :White to Off-White
Stability :Light Sensitive

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

4’-hydroxy Tamoxifen is one of five main phase I metabolites of tamoxifen , a well-known estrogen receptor antagonist in breasts but partial estrogen receptor agonist in endometrium. 4’-hydroxy Tamoxifen is a product of cytochrome P450 (CYP)2D6 and CYP2B6 activity. With the addition of a hydroxyl group, 4’-hydroxy tamoxifen has been shown to have a higher affinity for estrogen receptors compared to tamoxifen. At 10-100 μM, 4’-hydroxy tamoxifen is cytotoxic, in a non-apoptotic manner, to HEC-1B and HEC-1A human endometrial adenocarcinoma cell lines.