5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide
![5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide price.](/CAS/GIF/511296-88-1.gif)
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- $45 - $1054.14
- Product name: 5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide
- CAS: 511296-88-1
- MF: C16H16N2S.HBr
- MW: 349
- EINECS:
- MDL Number:MFCD02683960
- Synonyms:5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide;Cyclic Pifithrin-α hydrobromide;Pifithrin-beta;Cyclic Pifithrin-alpha HydrobroMide;5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide Pifithrin-β;2-(4-Methylphenyl)imidazo[2,1-b]-5,6,7,8-tetrahydrobenzothiazole hydrobromide;Cyclic PFT-α hydrobromide;Pifithrin-α, cyclic
18 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Chem-Impex
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
Package
- 5mg
- 10mg
- 20MG
- 25mg
- 50mg
- 100MG
- 250mg
- ManufacturerAK Scientific
- Product numberJ96509
- Product descriptionCyclic Pifithrin-alpha Hydrobromide
- Packaging5mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX5921
- Product descriptionCyclic Pifithrin-alpha Hydrobromide
- Packaging5mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001644
- Product descriptionCYCLIC PIFITHRIN-ALPHA HYDROBROMIDE 95.00%
- Packaging5MG
- Price$181.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4477
- Product descriptionCyclic Pifithrin-α hydrobromide
- Packaging5mg
- Price$48
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4477
- Product descriptionCyclic Pifithrin-α hydrobromide
- Packaging10mg
- Price$83
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4477
- Product descriptionCyclic Pifithrin-α hydrobromide
- Packaging25mg
- Price$131
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4477
- Product descriptionCyclic Pifithrin-α hydrobromide
- Packaging50mg
- Price$305
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14748
- Product descriptionCyclic Pifithrin-α (hydrobromide) ≥95%
- Packaging5mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14748
- Product descriptionCyclic Pifithrin-α (hydrobromide) ≥95%
- Packaging10mg
- Price$107
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14748
- Product descriptionCyclic Pifithrin-α (hydrobromide) ≥95%
- Packaging25mg
- Price$249
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14748
- Product descriptionCyclic Pifithrin-α (hydrobromide) ≥95%
- Packaging50mg
- Price$412
- Updated2024-03-01
- Buy
- ManufacturerChem-Impex
- Product number42452
- Product descriptionCyclicpifithrin-αhydrobromide,98%(HPLC) 98%(HPLC)
- Packaging20MG
- Price$300.16
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number42452
- Product descriptionCyclicpifithrin-αhydrobromide,≥98%(HPLC) ≥98%(HPLC)
- Packaging100MG
- Price$1054.14
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8144
- Product descriptionPifithrin-β >98%
- Packaging250mg
- Price$800
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberP4236
- Product descriptionCyclic Pifithrin-α hydrobromide ≥98% (HPLC)
- Packaging5mg
- Price$200
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberP4236
- Product descriptionCyclic Pifithrin-α hydrobromide ≥98% (HPLC)
- Packaging10mg
- Price$336
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | J96509 | Cyclic Pifithrin-alpha Hydrobromide | 5mg | $45 | 2021-12-16 | Buy |
| AK Scientific | X5921 | Cyclic Pifithrin-alpha Hydrobromide | 5mg | $119 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001644 | CYCLIC PIFITHRIN-ALPHA HYDROBROMIDE 95.00% | 5MG | $181.5 | 2021-12-16 | Buy |
| ApexBio Technology | A4477 | Cyclic Pifithrin-α hydrobromide | 5mg | $48 | 2021-12-16 | Buy |
| ApexBio Technology | A4477 | Cyclic Pifithrin-α hydrobromide | 10mg | $83 | 2021-12-16 | Buy |
| ApexBio Technology | A4477 | Cyclic Pifithrin-α hydrobromide | 25mg | $131 | 2021-12-16 | Buy |
| ApexBio Technology | A4477 | Cyclic Pifithrin-α hydrobromide | 50mg | $305 | 2021-12-16 | Buy |
| Cayman Chemical | 14748 | Cyclic Pifithrin-α (hydrobromide) ≥95% | 5mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 14748 | Cyclic Pifithrin-α (hydrobromide) ≥95% | 10mg | $107 | 2024-03-01 | Buy |
| Cayman Chemical | 14748 | Cyclic Pifithrin-α (hydrobromide) ≥95% | 25mg | $249 | 2024-03-01 | Buy |
| Cayman Chemical | 14748 | Cyclic Pifithrin-α (hydrobromide) ≥95% | 50mg | $412 | 2024-03-01 | Buy |
| Chem-Impex | 42452 | Cyclicpifithrin-αhydrobromide,98%(HPLC) 98%(HPLC) | 20MG | $300.16 | 2021-12-16 | Buy |
| Chem-Impex | 42452 | Cyclicpifithrin-αhydrobromide,≥98%(HPLC) ≥98%(HPLC) | 100MG | $1054.14 | 2021-12-16 | Buy |
| DC Chemicals | DC8144 | Pifithrin-β >98% | 250mg | $800 | 2021-12-16 | Buy |
| Sigma-Aldrich | P4236 | Cyclic Pifithrin-α hydrobromide ≥98% (HPLC) | 5mg | $200 | 2024-03-01 | Buy |
| Sigma-Aldrich | P4236 | Cyclic Pifithrin-α hydrobromide ≥98% (HPLC) | 10mg | $336 | 2024-03-01 | Buy |
Properties
storage temp. :-20°C
solubility :DMSO: soluble20mg/mL
form :powder to crystal
color :White to Almost white
Merck :14,7421
solubility :DMSO: soluble20mg/mL
form :powder to crystal
color :White to Almost white
Merck :14,7421
Safety Information
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Description
Pifithrin-α (PFT-α; ) is a reversible inhibitor of p53-dependent transcription and apoptosis. Cyclic PFT-α, also known as PFT-β, is a stable analog of PFT-α, formed by the condensation of pifithrin-α in solution. It inhibits the growth of the cancer cell lines IGROV-1, A2780, and HCT116 (IC50 = 23, 77, and 103 μM, respectively). At doses lower than those that inhibit growth, cyclic PFT-α induces autophagy in HCT116 cells and sensitizes IGROV-1 and H460 cells to anti-microtubule agents. In addition, 10 μM cyclic PFT-α blocks p53-dependent protection from DNA damage, induced by hydrogen peroxide or ultraviolet radiation, in melanocytes.Related product price
Suppliers and manufacturers
career henan chemical co
![5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide](https://img.chemicalbook.com/ProductImageEN/2019-12/small/1113a923-acfb-4d03-ac9d-6927d4fc7f9a.jpg)
ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Dayang Chem (Hangzhou) Co.,Ltd.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Nantong HI-FUTURE Biology Co., Ltd.
TargetMol Chemicals Inc.
PT CHEM GROUP LIMITED
GIHI CHEMICALS CO.,LIMITED
$1.00 /1g
5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide CAS:511296-88-1
5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazolehydrobromide CAS:511296-88-1