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ChemicalBook >> CAS DataBase List >> 5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-

5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-

5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- price.
  • $38 - $700
  • Product name: 5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-
  • CAS: 56990-57-9
  • MF: C19H13N3O7S2
  • MW: 459.45
  • EINECS:
  • MDL Number:MFCD09971104
  • Synonyms:5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-;8-Hydroxy-7-[(6-sulfo-2-naphthyl)azo]-5-quinolinesulfonicacid;NSC 87877;XGMFVZOKHBRUTL-QURGRASLSA-N;5-Quinolinesulfonicacid, 8-hydroxy-7-[2-(6-sulfo-2-naphthalenyl)diazenyl]-;NSC 87877(free acid);(7e)-8-oxo-7-[(6-sulfonaphthalen-2-yl)hydrazinylidene]quinoline-5-sulfonic Acid
17 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Tocris
  • Usbiological
Package
  • 50
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product numberSYN5277
  • Product descriptionNSC-87877
  • Packaging100mg
  • Price$202
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6405CA
  • Product description8-Hydroxy-7-(6-sulfo-naphthalen-2-ylazo)-quinoline-5-sulfonicacid
  • Packaging50mg
  • Price$241
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4544
  • Product descriptionNSC87877
  • Packaging50mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14908
  • Product descriptionNSC 87877 ≥98%
  • Packaging10mg
  • Price$38
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14908
  • Product descriptionNSC 87877 ≥98%
  • Packaging25mg
  • Price$79
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14908
  • Product descriptionNSC 87877 ≥98%
  • Packaging50mg
  • Price$130
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14908
  • Product descriptionNSC 87877 ≥98%
  • Packaging100mg
  • Price$220
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0014260
  • Product descriptionNSC-87877 >99.0%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0014260
  • Product descriptionNSC-87877 >99.0%
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0014260
  • Product descriptionNSC-87877 >99.0%
  • Packaging25mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0014260
  • Product descriptionNSC-87877 >99.0%
  • Packaging50mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0014260
  • Product descriptionNSC-87877 >99.0%
  • Packaging100mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10212
  • Product descriptionNSC-87877 >98%
  • Packaging100mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10212
  • Product descriptionNSC-87877 >98%
  • Packaging250mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number71776
  • Product descriptionNSC87877
  • Packaging100mg
  • Price$625
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number2613
  • Product descriptionNSC87877 ≥98%(HPLC)
  • Packaging50
  • Price$162
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5277 NSC-87877 100mg $202 2021-12-16 Buy
AK Scientific 6405CA 8-Hydroxy-7-(6-sulfo-naphthalen-2-ylazo)-quinoline-5-sulfonicacid 50mg $241 2021-12-16 Buy
ApexBio Technology A4544 NSC87877 50mg $147 2021-12-16 Buy
Cayman Chemical 14908 NSC 87877 ≥98% 10mg $38 2024-03-01 Buy
Cayman Chemical 14908 NSC 87877 ≥98% 25mg $79 2024-03-01 Buy
Cayman Chemical 14908 NSC 87877 ≥98% 50mg $130 2024-03-01 Buy
Cayman Chemical 14908 NSC 87877 ≥98% 100mg $220 2024-03-01 Buy
ChemScene CS-0014260 NSC-87877 >99.0% 5mg $60 2021-12-16 Buy
ChemScene CS-0014260 NSC-87877 >99.0% 10mg $100 2021-12-16 Buy
ChemScene CS-0014260 NSC-87877 >99.0% 25mg $200 2021-12-16 Buy
ChemScene CS-0014260 NSC-87877 >99.0% 50mg $350 2021-12-16 Buy
ChemScene CS-0014260 NSC-87877 >99.0% 100mg $600 2021-12-16 Buy
DC Chemicals DC10212 NSC-87877 >98% 100mg $350 2021-12-16 Buy
DC Chemicals DC10212 NSC-87877 >98% 250mg $700 2021-12-16 Buy
Medical Isotopes, Inc. 71776 NSC87877 100mg $625 2021-12-16 Buy
Tocris 2613 NSC87877 ≥98%(HPLC) 50 $162 2021-12-16 Buy

Properties

storage temp. :Store at +4°C
solubility :≥45.9 mg/mL in DMSO; insoluble in EtOH; ≥16.6 mg/mL in H2O with ultrasonic
form :Powder
color :Light brown to black

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

The Src homology region 2 domain-containing phosphatases (SHP) known as SHP-1 and SHP-2 act downstream of receptor and non-receptor tyrosine kinase to modulate signal transduction. NSC 87877 is a cell-permeable, inhibitor of both SHP-1 and SHP-2 (IC50 = 355 and 318 nM, respectively). It is much less effective against other protein tyrosine phosphatases and the dual-specificity phosphatase 26. Through its effects on SHP-1 or SHP-2, NSC 87877 blocks epidermal growth factor receptor-induced activation of Ras and ERK1/2 in HEK293 cells, stimulates store-operated calcium entry in response to thrombin in platelets, and increased acetylcholine receptor clustering in myotubes.