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ChemicalBook >> CAS DataBase List >> 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine

6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine

6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine price.
  • $117 - $4000
  • Product name: 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
  • CAS: 867017-68-3
  • MF: C18H13ClF2N6O
  • MW: 402.79
  • EINECS:
  • MDL Number:MFCD15528941
  • Synonyms:6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine;Rho Kinase Inhibitors;6-CHLORO-N4-[3,5-DIFLUORO-4-[(3-METHYL-1H-PYRROLO[2,3-B]PYRIDIN-4-YL)OXY]PHENYL]PYRIMIDIN-2,4-DIAMINE;TC-S 7001;Azaindole 1;RHO-KINASE INHIBITOR;RHO KINASE INHIBITOR;RHO-KINASE INHIBITOR; RHO KINASE INHIBITOR; ROCK;2,4-Pyrimidinediamine, 6-chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-
22 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • DC Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 1
  • 500μg
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number8778CS
  • Product descriptionROCKInhibitor
  • Packaging1mg
  • Price$336
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0316570
  • Product description6-CHLORO-N4-(3,5-DIFLUORO-4-[(3-METHYL-1H-PYRROLO-[2,3-B]PYRIDIN-4-YL)OXY]PHENYL)PYRIMIDIN-2,4-DIAMINE 95.00%
  • Packaging5MG
  • Price$496.33
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611769
  • Product descriptionAzaindole-1
  • Packaging10mg
  • Price$632.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611769
  • Product descriptionAzaindole-1
  • Packaging50mg
  • Price$1684.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC102609
  • Product description6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
  • Packaging5mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC102609
  • Product description6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
  • Packaging10mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC102609
  • Product description6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
  • Packaging25mg
  • Price$1700
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC102609
  • Product description6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
  • Packaging50mg
  • Price$2600
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC102609
  • Product description6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
  • Packaging100mg
  • Price$4000
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19129
  • Product descriptionTC-S 7001
  • Packaging500μg
  • Price$117
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19129
  • Product descriptionTC-S 7001
  • Packaging1mg
  • Price$186
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19129
  • Product descriptionTC-S 7001
  • Packaging5mg
  • Price$521
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM149760
  • Product description6-chloro-N4-(3,5-difluoro-4-((3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)pyrimidine-2,4-diamine 95%+
  • Packaging100mg
  • Price$1252
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0341
  • Product descriptionROCK-IN-2 99.46%
  • Packaging5mg
  • Price$431
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0341
  • Product descriptionROCK-IN-2 99.46%
  • Packaging10mg
  • Price$617
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0341
  • Product descriptionROCK-IN-2 99.46%
  • Packaging50mg
  • Price$1682
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8778CS ROCKInhibitor 1mg $336 2021-12-16 Buy
American Custom Chemicals Corporation HCH0316570 6-CHLORO-N4-(3,5-DIFLUORO-4-[(3-METHYL-1H-PYRROLO-[2,3-B]PYRIDIN-4-YL)OXY]PHENYL)PYRIMIDIN-2,4-DIAMINE 95.00% 5MG $496.33 2021-12-16 Buy
Biorbyt Ltd orb611769 Azaindole-1 10mg $632.4 2021-12-16 Buy
Biorbyt Ltd orb611769 Azaindole-1 50mg $1684.7 2021-12-16 Buy
Biosynth Carbosynth FC102609 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine 5mg $600 2021-12-16 Buy
Biosynth Carbosynth FC102609 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine 10mg $900 2021-12-16 Buy
Biosynth Carbosynth FC102609 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine 25mg $1700 2021-12-16 Buy
Biosynth Carbosynth FC102609 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine 50mg $2600 2021-12-16 Buy
Biosynth Carbosynth FC102609 6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine 100mg $4000 2021-12-16 Buy
Cayman Chemical 19129 TC-S 7001 500μg $117 2024-03-01 Buy
Cayman Chemical 19129 TC-S 7001 1mg $186 2024-03-01 Buy
Cayman Chemical 19129 TC-S 7001 5mg $521 2024-03-01 Buy
Chemenu CM149760 6-chloro-N4-(3,5-difluoro-4-((3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)pyrimidine-2,4-diamine 95%+ 100mg $1252 2021-12-16 Buy
ChemScene CS-0341 ROCK-IN-2 99.46% 5mg $431 2021-12-16 Buy
ChemScene CS-0341 ROCK-IN-2 99.46% 10mg $617 2021-12-16 Buy
ChemScene CS-0341 ROCK-IN-2 99.46% 50mg $1682 2021-12-16 Buy

Properties

Density :1.61
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO: Soluble; Ethanol: Soluble
form :A solid
pka :13.56±0.40(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

TC-S 7001 is a novel potent and highly selective azaindole-based inhibitor of Rho-kinase (ROCK). It exhibits long-acting vasodilator activity and decreases pulmonary and systemic arterial pressure in rats.

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