AMG-706
- $35 - $1805
- Product name: AMG-706
- CAS: 857876-30-3
- MF: C22H29N5O9P2
- MW: 569.441282
- EINECS:
- MDL Number:MFCD12407403
- Synonyms:Motesanib, Diphosphate Salt;AMG-706;Motesanib(AMG-706);Motesanib diphosphate;Motesanib diphosphate [usan];Unii-T6Q3060U91;N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide diphosphate;N-(2,3-Dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]-3-pyridinecarboxaMide Phosphate
31 prices
Selected condition:
Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Usbiological
Package
- 1mg
- 5MG
- 10MG
- 25MG
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 1000mg
- 10mM(in 1mL DMSO)
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0006359
- Product descriptionMOTESANIB DIPHOSPHATE 95.00%
- Packaging5MG
- Price$268.4
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0006359
- Product descriptionMOTESANIB DIPHOSPHATE 95.00%
- Packaging10MG
- Price$702.66
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0006359
- Product descriptionMOTESANIB DIPHOSPHATE 95.00%
- Packaging25MG
- Price$798.7
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5017
- Product descriptionMotesanibDiphosphate(AMG-706)
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5017
- Product descriptionMotesanibDiphosphate(AMG-706)
- Packaging50mg
- Price$155
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIFK0030
- Product descriptionMotesanibDiphosphateSalt
- Packaging10mg
- Price$66
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIFK0030
- Product descriptionMotesanibDiphosphateSalt
- Packaging50mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIFK0030
- Product descriptionMotesanibDiphosphateSalt
- Packaging100mg
- Price$348
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2554
- Product descriptionMotesanib Diphosphate
- Packaging10mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2554
- Product descriptionMotesanib Diphosphate
- Packaging100mg
- Price$185
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2554
- Product descriptionMotesanib Diphosphate
- Packaging1g
- Price$1350
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181060
- Product descriptionMotesanib Diphosphate (AMG-706) >98%
- Packaging100mg
- Price$606.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181060
- Product descriptionMotesanib Diphosphate (AMG-706) >98%
- Packaging250mg
- Price$912.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181060
- Product descriptionMotesanib Diphosphate (AMG-706) >98%
- Packaging1000mg
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM26093
- Product descriptionMotesanib diphosphate
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM26093
- Product descriptionMotesanib diphosphate
- Packaging50mg
- Price$262.5
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
American Custom Chemicals Corporation | API0006359 | MOTESANIB DIPHOSPHATE 95.00% | 5MG | $268.4 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0006359 | MOTESANIB DIPHOSPHATE 95.00% | 10MG | $702.66 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0006359 | MOTESANIB DIPHOSPHATE 95.00% | 25MG | $798.7 | 2021-12-16 | Buy |
ApexBio Technology | A5017 | MotesanibDiphosphate(AMG-706) | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
ApexBio Technology | A5017 | MotesanibDiphosphate(AMG-706) | 50mg | $155 | 2021-12-16 | Buy |
Apolloscientific | BIFK0030 | MotesanibDiphosphateSalt | 10mg | $66 | 2021-12-16 | Buy |
Apolloscientific | BIFK0030 | MotesanibDiphosphateSalt | 50mg | $218 | 2021-12-16 | Buy |
Apolloscientific | BIFK0030 | MotesanibDiphosphateSalt | 100mg | $348 | 2021-12-16 | Buy |
AvaChem | 2554 | Motesanib Diphosphate | 10mg | $35 | 2021-12-16 | Buy |
AvaChem | 2554 | Motesanib Diphosphate | 100mg | $185 | 2021-12-16 | Buy |
AvaChem | 2554 | Motesanib Diphosphate | 1g | $1350 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181060 | Motesanib Diphosphate (AMG-706) >98% | 100mg | $606.9 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181060 | Motesanib Diphosphate (AMG-706) >98% | 250mg | $912.9 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181060 | Motesanib Diphosphate (AMG-706) >98% | 1000mg | $1802 | 2021-12-16 | Buy |
Biosynth Carbosynth | FM26093 | Motesanib diphosphate | 10mg | $75 | 2021-12-16 | Buy |
Biosynth Carbosynth | FM26093 | Motesanib diphosphate | 50mg | $262.5 | 2021-12-16 | Buy |
Properties
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :≥28.45 mg/mL in DMSO; insoluble in H2O; ≥3.47 mg/mL in EtOH with ultrasonic
form :Powder
color :White to off-white
solubility :≥28.45 mg/mL in DMSO; insoluble in H2O; ≥3.47 mg/mL in EtOH with ultrasonic
form :Powder
color :White to off-white
Safety Information
Symbol(GHS): | ||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | |||||||||||||||||||||||||||||||||||
Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
AMG 706 is a multikinase inhibitor that predominantly targets receptor tyrosine kinases, including VEGFR1, VEGFR2, VEGFR3, c-Kit, PDGFR, and RET (IC50s = 2, 3, 6, 8, 84, and 59 nM, respectively). It also potently inhibits CSF1R and ZAK (IC50s = 5.6 and 8 nM, respectively), as well as several mutants of c-Kit. AMG 706 inhibits the proliferation of human endothelial cells induced by VEGF but not FGF. Oral administration of AMG 706 blocks VEGF-induced angiogenesis in the rat corneal model and induces regression of established A431 xenografts in mice.More related product prices
PD184352 DAPT PD 0325901 Tozasertib Linifanib (ABT-869) Axitinib MotesanibRelated product price
- PD184352
$20-2120 - DAPT
$28-2776 - PD 0325901
$8-1680
Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Hubei Jusheng Technology Co.,Ltd.
BOC Sciences
Chongqing Chemdad Co., Ltd
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
TargetMol Chemicals Inc.
Dideu Industries Group Limited
Dayang Chem (Hangzhou) Co.,Ltd.
Zhejiang J&C Biological Technology Co.,Limited