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ChemicalBook >> CAS DataBase List >> APF

APF

APF price.
  • $152 - $1204
  • Product name: APF
  • CAS: 359010-70-1
  • MF: C26H17NO5
  • MW: 423.42
  • EINECS:
  • MDL Number:MFCD08062220
  • Synonyms:APF;2-[6-(4'-AMINO)PHENOXY-3H-XANTHEN-3-ON-9-YL]BENZOIC ACID;2-[6-(4-AMINOPHENOXY)-3-OXO-3H-XANTHEN-9-YL]-BENZOIC ACID;AMINOPHENYL FLUORESCEIN;3'-(4-aminophenoxy)-6'-hydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one;2-[3-(4-aminophenoxy)-6-oxoxanthen-9-yl]benzoic acid;Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3'-(4-aminophenoxy)-6'-hydroxy-
4 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • 5mg
  • ManufacturerAK Scientific
  • Product number1619AH
  • Product description2-[6-(4-Aminophenoxy)-3-oxo-3H-xanthen-9-yl]-benzoicacid
  • Packaging1mg
  • Price$418
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10157
  • Product descriptionAPF ≥98%
  • Packaging500μg
  • Price$152
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10157
  • Product descriptionAPF ≥98%
  • Packaging1mg
  • Price$288
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10157
  • Product descriptionAPF ≥98%
  • Packaging5mg
  • Price$1204
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1619AH 2-[6-(4-Aminophenoxy)-3-oxo-3H-xanthen-9-yl]-benzoicacid 1mg $418 2021-12-16 Buy
Cayman Chemical 10157 APF ≥98% 500μg $152 2024-03-01 Buy
Cayman Chemical 10157 APF ≥98% 1mg $288 2024-03-01 Buy
Cayman Chemical 10157 APF ≥98% 5mg $1204 2024-03-01 Buy

Properties

Boiling point :677.7±55.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF:20.0(Max Conc. mg/mL);47.23(Max Conc. mM)
DMSO:10.0(Max Conc. mg/mL);23.62(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);23.62(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:3):0.5(Max Conc. mg/mL);1.18(Max Conc. mM) form :Pale yellow liquid.
pka :9.61±0.20(Predicted)
color :Colorless to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including, neurodegeneration and aging, cancer, and infectious diseases. There are a number of fluorescent reagents that can be used to detect free radicals, such as 2,7-dichlorodihydrofluorescein (DCDHF), but they have significant limitations due to their facile oxidation by light and numerous non-radical oxidants such as hydrogen peroxide (H2O2). APF is an aromatic amino-fluorescein derivative that has little intrinsic fluorescence. It undergoes oxidation only by the hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, but is inert to NO, H2O2, superoxide, and other oxidants. Upon oxidation, APF is converted to the highly fluorescent molecule fluorescein, allowing the simple direct detection of highly reactive biological radicals.

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