Afatinib
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- $26 - $912.9
- Product name: Afatinib
- CAS: 850140-72-6
- MF: C24H25ClFN5O3
- MW: 485.94
- EINECS:
- MDL Number:MFCD12407405
- Synonyms:Afatinib;(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide;4-[(3-chloro-4-fluorophenyl)aMino]-6-{[4-(N,N-diMethylaMino)-1-oxo-2-buten-1-yl]aMino}-7-((S)-tetrahydrofuran-3-yloxy)-quinazoline;2-ButenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(diMethylaMino)-, (2E)-;(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dime;Afatinib API;Afatinib(BIBW2992MA2);GILOTRIF(AFATINIB)
37 prices
Selected condition：
Brand
- AK Scientific
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Medical Isotopes, Inc.
- TCI Chemical
- TRC
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- 5g
- 1 mg
- 5 mg
- 10 mg
- 25 mg
- 50 mg
- ManufacturerAK Scientific
- Product number3123AC
- Product description(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
- Packaging10mg
- Price$116
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3123AC
- Product description(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
- Packaging100mg
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3123AC
- Product description(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
- Packaging250mg
- Price$163
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3123AC
- Product description(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
- Packaging1g
- Price$244
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3123AC
- Product description(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
- Packaging5g
- Price$905
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3098
- Product descriptionAfatinib
- Packaging5mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3098
- Product descriptionAfatinib
- Packaging25mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3098
- Product descriptionAfatinib
- Packaging100mg
- Price$149
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3098
- Product descriptionAfatinib
- Packaging1g
- Price$690
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611507
- Product descriptionAfatinib
- Packaging100mg
- Price$397.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611507
- Product descriptionAfatinib
- Packaging250mg
- Price$606.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611507
- Product descriptionAfatinib
- Packaging1g
- Price$912.9
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBA164141
- Product descriptionAfatinib
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC17230
- Product descriptionAfatinib
- Packaging100mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC17230
- Product descriptionAfatinib
- Packaging250mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBA164141
- Product descriptionAfatinib
- Packaging50mg
- Price$262.5
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3123AC | (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide | 10mg | $116 | 2021-12-16 | Buy |
| AK Scientific | 3123AC | (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide | 100mg | $145 | 2021-12-16 | Buy |
| AK Scientific | 3123AC | (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide | 250mg | $163 | 2021-12-16 | Buy |
| AK Scientific | 3123AC | (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide | 1g | $244 | 2021-12-16 | Buy |
| AK Scientific | 3123AC | (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide | 5g | $905 | 2021-12-16 | Buy |
| AvaChem | 3098 | Afatinib | 5mg | $35 | 2021-12-16 | Buy |
| AvaChem | 3098 | Afatinib | 25mg | $59 | 2021-12-16 | Buy |
| AvaChem | 3098 | Afatinib | 100mg | $149 | 2021-12-16 | Buy |
| AvaChem | 3098 | Afatinib | 1g | $690 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611507 | Afatinib | 100mg | $397.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611507 | Afatinib | 250mg | $606.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611507 | Afatinib | 1g | $912.9 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BA164141 | Afatinib | 10mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC17230 | Afatinib | 100mg | $95 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC17230 | Afatinib | 250mg | $175 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BA164141 | Afatinib | 50mg | $262.5 | 2021-12-16 | Buy |
Properties
Melting point :102 °C
Boiling point :676.9±55.0 °C(Predicted)
Density :1.380
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
form :Yellow powder.
pka :11.79±0.43(Predicted)
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Boiling point :676.9±55.0 °C(Predicted)
Density :1.380
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
form :Yellow powder.
pka :11.79±0.43(Predicted)
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Safety Information
| Symbol(GHS): |
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| Signal word: | Danger | ||||||||
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Description
Afatinib (850140-72-6) is a clinically useful kinase inhibitor approved for the treatment of non-small cell lung cancer. It is a potent and highly selective inhibitor of mutant and wild-type EGFR (IC50= 0.5 nM) and HER2 (IC50?= 14 nM).More related product prices
Afatinib-d6 TRANS-4-AMINOCROTONIC ACID 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE Crizotinib Apatinib Axitinib lenvatinib Mesylate Lenvatinib 162012-69-3 Afatinib (BIBW 2992) 86087-23-2 BIBW2992 DiMaleate 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine trans-4-Dimethylaminocrotonic acid hydrochloride Nintedanib Ethanesulfonate Salt AZD-9291 Lapatinib ditosylate Regorafenib 4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3S)-tetrahydro-3-furanyl]oxy]-Related product price
- Afatinib-d6
$153-1610 - TRANS-4-AMINOCROTONIC ACID
$65-1176 - 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE
$125-2194.5
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