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ChemicalBook >> CAS DataBase List >> BMS 303141

BMS 303141

BMS 303141 price.
  • $30 - $2691.1
  • Product name: BMS 303141
  • CAS: 943962-47-8
  • MF: C19H15Cl2NO4S
  • MW: 424.3
  • EINECS:
  • MDL Number:MFCD25976797
  • Synonyms:BMS 303141;BMS30314;3,5-dichloro-2-hydroxy-N-(4-Methoxybiphenyl-3-yl)benzenesulfonaMide;3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)benzenesulfonamide;3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)-benzenesulfonamide BMS 303141;BMS 303141, >=98%;3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide;CS-887
39 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 1mg
  • 5mg
  • 10
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1000mg
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number3497AH
  • Product descriptionBMS-303141
  • Packaging250mg
  • Price$397
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA169881
  • Product description3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+%
  • Packaging1mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA169881
  • Product description3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+%
  • Packaging5mg
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA169881
  • Product description3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+%
  • Packaging10mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA169881
  • Product description3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+%
  • Packaging50mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA169881
  • Product description3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+%
  • Packaging100mg
  • Price$163
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA169881
  • Product description3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+%
  • Packaging250mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA169881
  • Product description3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+%
  • Packaging1g
  • Price$631
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0009814
  • Product descriptionBMS-303141 95.00%
  • Packaging5MG
  • Price$451.43
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1079
  • Product descriptionBMS-303141
  • Packaging10mM(in 1mL DMSO)
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1079
  • Product descriptionBMS-303141
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1079
  • Product descriptionBMS-303141
  • Packaging25mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1079
  • Product descriptionBMS-303141
  • Packaging50mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2506
  • Product descriptionBMS303141 100%
  • Packaging50mg
  • Price$319
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545898
  • Product descriptionbMS-303141 >98%
  • Packaging5mg
  • Price$190.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545898
  • Product descriptionbMS-303141 >98%
  • Packaging25mg
  • Price$521.9
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3497AH BMS-303141 250mg $397 2021-12-16 Buy
Ambeed A169881 3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+% 1mg $30 2021-12-16 Buy
Ambeed A169881 3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+% 5mg $51 2021-12-16 Buy
Ambeed A169881 3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+% 10mg $66 2021-12-16 Buy
Ambeed A169881 3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+% 50mg $112 2021-12-16 Buy
Ambeed A169881 3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+% 100mg $163 2021-12-16 Buy
Ambeed A169881 3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+% 250mg $250 2021-12-16 Buy
Ambeed A169881 3,5-Dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide 98+% 1g $631 2021-12-16 Buy
American Custom Chemicals Corporation INB0009814 BMS-303141 95.00% 5MG $451.43 2021-12-16 Buy
ApexBio Technology B1079 BMS-303141 10mM(in 1mL DMSO) $72 2021-12-16 Buy
ApexBio Technology B1079 BMS-303141 10mg $85 2021-12-16 Buy
ApexBio Technology B1079 BMS-303141 25mg $170 2021-12-16 Buy
ApexBio Technology B1079 BMS-303141 50mg $300 2021-12-16 Buy
Axon Medchem Axon2506 BMS303141 100% 50mg $319 2021-12-16 Buy
Biorbyt Ltd orb545898 bMS-303141 >98% 5mg $190.4 2021-12-16 Buy
Biorbyt Ltd orb545898 bMS-303141 >98% 25mg $521.9 2021-12-16 Buy

Properties

Boiling point :591.5±60.0 °C(Predicted)
Density :1.462±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :4.94±0.48(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ATP citrate lyase (ACL) catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a cofactor. The ACL-dependent synthesis of acetyl-CoA is important for the de novo synthesis of fatty acids and cholesterol. Furthermore, as a key enzyme for linking glucose and lipid metabolism, ACL is thought to contribute to the Warburg effect in cancer cells. BMS 303141 is a cell-permeable, 2-hydroxy-N-arylbenzenesulfonamide that inhibits ACL with an IC50 value of 0.13 μM. At an oral dose of 100 mg/kg/day, BMS 303141 has been reported to reduce weight gain and lower plasma cholesterol, triglycerides, and glucose in a mouse model of hyperlipidemia.

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