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ChemicalBook >> CAS DataBase List >> Brefeldin A

Brefeldin A

Brefeldin A price.
  • $28 - $2395.3
  • Product name: Brefeldin A
  • CAS: 20350-15-6
  • MF: C16H24O4
  • MW: 280.36
  • EINECS:606-528-3
  • MDL Number:MFCD12913297
  • Synonyms:NSC 107456;(1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-Methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one;Ascotoxin, Cyanein, DecuMbin;Brefeldin A, FroM EupenicilliuM brefeldianuM;NECTROLIDE;SYNERGISIDIN;4h-cyclopent(f)oxacyclotridecin-4-one,1,6,7,8,9,11a-beta,12,13,14,14a-alpha-de ;cahydro-1-beta-13-alpha-dihydroxy-6-beta-methyl-
73 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 2mg
  • 1unit
  • 10mM(in 1mL DMSO)
  • 10mg
  • 20mg
  • 5mg
  • 5
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 300mg
  • 1g
  • 200μL
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0018-M025
  • Product description(+)-BrefeldinA ≥98%(HPLC)
  • Packaging25mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62340
  • Product descriptionBrefeldin A, 99%
  • Packaging10mg
  • Price$142
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62340
  • Product descriptionBrefeldin A, 99%
  • Packaging25mg
  • Price$314
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62340
  • Product descriptionBrefeldin A, 99%
  • Packaging50mg
  • Price$519
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA156234
  • Product description(1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one 98+%
  • Packaging5mg
  • Price$36
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156234
  • Product description(1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one 98+%
  • Packaging10mg
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156234
  • Product description(1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one 98+%
  • Packaging25mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156234
  • Product description(1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one 98+%
  • Packaging50mg
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156234
  • Product description(1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one 98+%
  • Packaging100mg
  • Price$407
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156234
  • Product description(1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one 98+%
  • Packaging250mg
  • Price$607
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156234
  • Product description(1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one 98+%
  • Packaging1g
  • Price$1558
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0009739
  • Product descriptionBREFELDIN A 95.00%
  • Packaging10MG
  • Price$628.44
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0009739
  • Product descriptionBREFELDIN A 95.00%
  • Packaging100MG
  • Price$824.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1400
  • Product descriptionBrefeldin A
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1400
  • Product descriptionBrefeldin A
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1400
  • Product descriptionBrefeldin A
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0018-M025 (+)-BrefeldinA ≥98%(HPLC) 25mg $110 2021-12-16 Buy
Alfa Aesar J62340 Brefeldin A, 99% 10mg $142 2024-03-01 Buy
Alfa Aesar J62340 Brefeldin A, 99% 25mg $314 2024-03-01 Buy
Alfa Aesar J62340 Brefeldin A, 99% 50mg $519 2024-03-01 Buy
Ambeed A156234 (1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one 98+% 5mg $36 2021-12-16 Buy
Ambeed A156234 (1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one 98+% 10mg $51 2021-12-16 Buy
Ambeed A156234 (1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one 98+% 25mg $115 2021-12-16 Buy
Ambeed A156234 (1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one 98+% 50mg $226 2021-12-16 Buy
Ambeed A156234 (1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one 98+% 100mg $407 2021-12-16 Buy
Ambeed A156234 (1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one 98+% 250mg $607 2021-12-16 Buy
Ambeed A156234 (1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one 98+% 1g $1558 2021-12-16 Buy
American Custom Chemicals Corporation INB0009739 BREFELDIN A 95.00% 10MG $628.44 2021-12-16 Buy
American Custom Chemicals Corporation INB0009739 BREFELDIN A 95.00% 100MG $824.9 2021-12-16 Buy
ApexBio Technology B1400 Brefeldin A 1unit $28 2021-12-16 Buy
ApexBio Technology B1400 Brefeldin A 5mg $50 2021-12-16 Buy
ApexBio Technology B1400 Brefeldin A 10mM(in 1mL DMSO) $60 2021-12-16 Buy

Properties

Melting point :200-205 °C
Boiling point :492.7±45.0 °C(Predicted)
alpha :93 º (C=2 IN MEOH)
Density :1.108±0.06 g/cm3(Predicted)
vapor pressure :0.56 hPa ( 20 °C)
Flash point :87 °C
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :methanol: 10 mg/mL, clear, colorless to faintly yellow
pka :12.92±0.60(Predicted)
form :Crystalline Powder
color :White to almost white
Water Solubility :Soluble in dimethylsulfoxide, dichloromethane and ethanol. Slightly soluble in water.
Merck :13,1355
BRN :25191
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :QSECOIOBNZLGOD-OBCVZTHZSA-N
CAS DataBase Reference :20350-15-6

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Brefeldin A (BFA) is a natural fungal metabolite which has been used extensively to study intracellular transport by vesicles or endosomes. Early studies demonstrated that BFA reversibly interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum. BFA directly and reversibly inhibits Sec7 domain-containing guanine-exchange factors which are necessary for ADP-ribosylation factor activation associated with vesicular transport (IC50 = ~10 μM). BFA is used to study endosomal trafficking and function in cells of plants as well as those of fungi, invertebrates, and vertebrates.

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