CALPHOSTIN C
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- $142 - $890
- Product name: CALPHOSTIN C
- CAS: 121263-19-2
- MF: C44H38O14
- MW: 790.76
- EINECS:
- MDL Number:MFCD00133155
- Synonyms:CALPHOSTIN C;CALPHOSTIN C FROM CLADOSPORIUMCLADOSPORI OIDES;UCN-1028C;(R)-Calphostin C;1-[(R)-2-(4-Hydroxyphenoxycarbonyloxy)propyl]-2,6,7,11-tetramethoxy-4,9-dihydroxy-12-[(R)-2-(benzoyloxy)propyl]-3,10-dihydroperylene-3,10-dione;4,9-Dihydroxy-12-[(R)-2-(4-hydroxyphenyloxy)carbonyloxypropyl]-2,6,7,11-tetramethoxy-1-[(R)-2-benzoyloxypropyl]perylene-3,10-dione;Calphostin C,98%;Calphostin CUCN-1028C
13 prices
Selected condition：
Brand
- Adipogen Life Sciences
- Alfa Aesar
- ApexBio Technology
- Cayman Chemical
- CSNpharm
- Sigma-Aldrich
- Tocris
- Usbiological
Package
- 50μg
- 100ug
- 100μg
- 0.1mg
- 500μg
- 1mg
- 100U
- 100microg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0430-M001
- Product descriptionCalphostinC ≥95%(HPLC)
- Packaging1mg
- Price$890
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60647
- Product descriptionCalphostin C, 95%
- Packaging100microg
- Price$238
- Updated2023-06-20
- Buy
- ManufacturerApexBio Technology
- Product numberB6807
- Product descriptionCalphostinC
- Packaging100ug
- Price$308
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15383
- Product descriptionCalphostin C ≥95%
- Packaging100μg
- Price$142
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15383
- Product descriptionCalphostin C ≥95%
- Packaging500μg
- Price$603
- Updated2024-03-01
- Buy
- ManufacturerCSNpharm
- Product numberCSN22738
- Product descriptionCalphostinC
- Packaging1mg
- Price$436
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number208725
- Product descriptionCalphostin C, Cladosporium cladosporioides - CAS 121263-19-2 - Calbiochem Acellpermeable,highlyspecificinhibitorofproteinkinaseC(IC??=50nM)t
- Packaging50μg
- Price$154
- Updated2023-01-07
- Buy
- ManufacturerSigma-Aldrich
- Product number208725
- Product descriptionCalphostin C, Cladosporium cladosporioides - CAS 121263-19-2 - Calbiochem Acellpermeable,highlyspecificinhibitorofproteinkinaseC(IC??=50nM)t
- Packaging100μg
- Price$264
- Updated2023-01-07
- Buy
- ManufacturerSigma-Aldrich
- Product numberC6303
- Product descriptionCalphostin C from Cladosporium cladosporioides ≥90% (HPLC), powder
- Packaging1mg
- Price$812
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberC6303
- Product descriptionCalphostin C from Cladosporium cladosporioides ≥90% (HPLC), powder
- Packaging0.1mg
- Price$254.4
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number1626
- Product descriptionCalphostinC ≥98%(HPLC)
- Packaging100U
- Price$212
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number207099
- Product descriptionCalphostin C
- Packaging100ug
- Price$342
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product numberC1035-38
- Product descriptionCalphostin C
- Packaging100ug
- Price$426
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0430-M001 | CalphostinC ≥95%(HPLC) | 1mg | $890 | 2021-12-16 | Buy |
| Alfa Aesar | J60647 | Calphostin C, 95% | 100microg | $238 | 2023-06-20 | Buy |
| ApexBio Technology | B6807 | CalphostinC | 100ug | $308 | 2021-12-16 | Buy |
| Cayman Chemical | 15383 | Calphostin C ≥95% | 100μg | $142 | 2024-03-01 | Buy |
| Cayman Chemical | 15383 | Calphostin C ≥95% | 500μg | $603 | 2024-03-01 | Buy |
| CSNpharm | CSN22738 | CalphostinC | 1mg | $436 | 2021-12-16 | Buy |
| Sigma-Aldrich | 208725 | Calphostin C, Cladosporium cladosporioides - CAS 121263-19-2 - Calbiochem Acellpermeable,highlyspecificinhibitorofproteinkinaseC(IC??=50nM)t | 50μg | $154 | 2023-01-07 | Buy |
| Sigma-Aldrich | 208725 | Calphostin C, Cladosporium cladosporioides - CAS 121263-19-2 - Calbiochem Acellpermeable,highlyspecificinhibitorofproteinkinaseC(IC??=50nM)t | 100μg | $264 | 2023-01-07 | Buy |
| Sigma-Aldrich | C6303 | Calphostin C from Cladosporium cladosporioides ≥90% (HPLC), powder | 1mg | $812 | 2024-03-01 | Buy |
| Sigma-Aldrich | C6303 | Calphostin C from Cladosporium cladosporioides ≥90% (HPLC), powder | 0.1mg | $254.4 | 2024-03-01 | Buy |
| Tocris | 1626 | CalphostinC ≥98%(HPLC) | 100U | $212 | 2021-12-16 | Buy |
| Usbiological | 207099 | Calphostin C | 100ug | $342 | 2021-12-16 | Buy |
| Usbiological | C1035-38 | Calphostin C | 100ug | $426 | 2021-12-16 | Buy |
Properties
Boiling point :1039.8±65.0 °C(Predicted)
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMF: 1 mg/mL
form :powder
pka :7.30±0.20(Predicted)
color :red to brown
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMF: 1 mg/mL
form :powder
pka :7.30±0.20(Predicted)
color :red to brown
Safety Information
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Description
Calphostin C is a metabolite of the fungus C. cladosporioides that specifically inhibits protein kinase C (PKC) (IC50 = 50 nM versus an IC50 > 50 μM for PKA) by competing at the binding site for diacylglycerol and phorbol esters. As a polycyclic hydrocarbon with strong absorbance in the visible and ultraviolet ranges, activation of this compound is strictly dependent on exposure to light. Independent of PKC, calphostin C also directly inhibits phospholipase D1 and D2 (IC50s = 100 nM). It demonstrates antitumor activity, inhibiting cell growth and promoting apoptosis in HeLa S3 and MCF-7 cells with IC50 values of 0.23 and 0.18 μM, respectively.More related product prices
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