CX-5461
|
- $28 - $2900
- Product name: CX-5461
- CAS: 1138549-36-6
- MF: C27H27N7O2S
- MW: 513.61
- EINECS:
- MDL Number:MFCD21609261
- Synonyms:CX-5461;2-(4-Methyl-1,4-diazepan-1-yl)-N-((5-Methylpyrazin-2-yl)Methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxaMide;2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-N-[(5-methyl-2-pyrazinyl)methyl]-5-oxo-5H-benzothiazolo[3,2-a][1,8]naphthyridine-6-carboxamide;CX-5461/CX5461;2-(Hexahydro-4-Methyl-1H-1,4-diazepin-1-yl)-N-[(5-Methyl-2-pyrazinyl)Methyl]-5-oxo-5H-benzothiazolo[3,2-a][1,8]napht;5H-Benzothiazolo[3,2-a][1,8]naphthyridine-6-carboxamide, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-N-[(5-methyl-2-pyrazinyl)methyl]-5-oxo-;CX-5461;CX 5461;CX5461;CX-5461 500MG
21 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
Package
- 1mg
- 1unit
- 5MG
- 2x5mg
- 10mg
- 50mg
- 100mg
- 250mg
- 5G
- ManufacturerAdipogen Life Sciences
- Product numberSYN-3031-M050
- Product descriptionCX-5461 ≥95%
- Packaging50mg
- Price$853
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN3031
- Product descriptionCX-5461
- Packaging10mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001389
- Product descriptionCX-5461 95.00%
- Packaging5MG
- Price$412
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001389
- Product descriptionCX-5461 95.00%
- Packaging5G
- Price$2900
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8337
- Product descriptionCX-5461
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8337
- Product descriptionCX-5461
- Packaging5mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8337
- Product descriptionCX-5461
- Packaging10mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8337
- Product descriptionCX-5461
- Packaging50mg
- Price$540
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60086
- Product descriptionCX-5461 ≥98%
- Packaging10mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2173
- Product descriptionCX5461 99%
- Packaging2x5mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18392
- Product descriptionCX-5461 ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18392
- Product descriptionCX-5461 ≥98%
- Packaging5mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18392
- Product descriptionCX-5461 ≥98%
- Packaging10mg
- Price$231
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18392
- Product descriptionCX-5461 ≥98%
- Packaging50mg
- Price$957
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0568
- Product descriptionCX-5461 98.13%
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0568
- Product descriptionCX-5461 98.13%
- Packaging10mg
- Price$192
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-3031-M050 | CX-5461 ≥95% | 50mg | $853 | 2021-12-16 | Buy |
| AK Scientific | SYN3031 | CX-5461 | 10mg | $270 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001389 | CX-5461 95.00% | 5MG | $412 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001389 | CX-5461 95.00% | 5G | $2900 | 2021-12-16 | Buy |
| ApexBio Technology | A8337 | CX-5461 | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A8337 | CX-5461 | 5mg | $110 | 2021-12-16 | Buy |
| ApexBio Technology | A8337 | CX-5461 | 10mg | $170 | 2021-12-16 | Buy |
| ApexBio Technology | A8337 | CX-5461 | 50mg | $540 | 2021-12-16 | Buy |
| Arctom | CFN60086 | CX-5461 ≥98% | 10mg | $198 | 2021-12-16 | Buy |
| Axon Medchem | Axon2173 | CX5461 99% | 2x5mg | $198 | 2021-12-16 | Buy |
| Cayman Chemical | 18392 | CX-5461 ≥98% | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 18392 | CX-5461 ≥98% | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 18392 | CX-5461 ≥98% | 10mg | $231 | 2024-03-01 | Buy |
| Cayman Chemical | 18392 | CX-5461 ≥98% | 50mg | $957 | 2024-03-01 | Buy |
| ChemScene | CS-0568 | CX-5461 98.13% | 5mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-0568 | CX-5461 98.13% | 10mg | $192 | 2021-12-16 | Buy |
Properties
Boiling point :739.9±60.0 °C(Predicted)
Density :1.45
storage temp. :+2C to +8C
solubility :insoluble in H2O; insoluble in EtOH; insoluble in DMSO
form :Light beige powder
pka :8.53±0.20(Predicted)
color :White to yellow
Density :1.45
storage temp. :+2C to +8C
solubility :insoluble in H2O; insoluble in EtOH; insoluble in DMSO
form :Light beige powder
pka :8.53±0.20(Predicted)
color :White to yellow
Safety Information
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Description
CX-5461 is an inhibitor of ribosomal RNA (rRNA) synthesis. It selectively inhibits RNA polymerase I-driven transcription of rRNA in HCT-116, A375, and MIA PaCa-2 tumor cells (IC50s = 142, 113, and 54 nM, respectively) without affecting RNA polymerase II (IC50 > 25μM), DNA replication, or protein translation. At 50 mg/kg, CX-5461 demonstrates in vivo antitumor activity against human solid tumors in mouse xenograft models.More related product prices
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