Conivaptan hydrochloride
|
- $15 - $1200
- Product name: Conivaptan hydrochloride
- CAS: 168626-94-6
- MF: C32H26N4O2.HCl
- MW: 535.04
- EINECS:1312995-182-4
- MDL Number:MFCD00945712
- Synonyms:(1,1'-Biphenyl)-2-carboxamide, N-(4-((4,5-dihydro-2-methylimidazo(4,5-D)(1)benzazepin-6(1H)-yl)carbonyl)phenyl)-, monohydrochloride;Conivaptan HCl;Conivaptan hydrochloride [usan];Unii-75L57R6X36;Vaprisol;Conivaptan hydrochkoride;N-[4-[(4,5-Dihydro-2-MethyliMidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-Biphenyl]-2-carboxaMide Hydrochloride;Conivaptan HCI
38 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Tocris
- TRC
Package
- 10mg
- 10
- 5mg
- 25mg
- 50
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product numberJ97032
- Product descriptionConivaptanhydrochloride
- Packaging250mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ97032
- Product descriptionConivaptanhydrochloride
- Packaging5g
- Price$1200
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA277387
- Product descriptionN-(4-(2-Methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamidehydrochloride 98+%
- Packaging5mg
- Price$20
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA277387
- Product descriptionN-(4-(2-Methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamidehydrochloride 98+%
- Packaging50mg
- Price$66
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA277387
- Product descriptionN-(4-(2-Methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamidehydrochloride 98+%
- Packaging250mg
- Price$98
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA277387
- Product descriptionN-(4-(2-Methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamidehydrochloride 98+%
- Packaging100mg
- Price$98
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA277387
- Product descriptionN-(4-(2-Methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamidehydrochloride 98+%
- Packaging1g
- Price$833
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA277387
- Product descriptionN-(4-(2-Methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamidehydrochloride 98+%
- Packaging5g
- Price$833
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8402
- Product descriptionConivaptanHCl
- Packaging10mg
- Price$77
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8402
- Product descriptionConivaptanHCl
- Packaging10mM(in 1mL DMSO)
- Price$88
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS504271
- Product descriptionConivaptanhydrochloride ≥98%
- Packaging5mg
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS504271
- Product descriptionConivaptanhydrochloride ≥98%
- Packaging10mg
- Price$20
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS504271
- Product descriptionConivaptanhydrochloride ≥98%
- Packaging50mg
- Price$34
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS504271
- Product descriptionConivaptanhydrochloride ≥98%
- Packaging100mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS504271
- Product descriptionConivaptanhydrochloride ≥98%
- Packaging250mg
- Price$97
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS504271
- Product descriptionConivaptanhydrochloride ≥98%
- Packaging1g
- Price$228
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | J97032 | Conivaptanhydrochloride | 250mg | $160 | 2021-12-16 | Buy |
| AK Scientific | J97032 | Conivaptanhydrochloride | 5g | $1200 | 2021-12-16 | Buy |
| Ambeed | A277387 | N-(4-(2-Methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamidehydrochloride 98+% | 5mg | $20 | 2021-12-16 | Buy |
| Ambeed | A277387 | N-(4-(2-Methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamidehydrochloride 98+% | 50mg | $66 | 2021-12-16 | Buy |
| Ambeed | A277387 | N-(4-(2-Methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamidehydrochloride 98+% | 250mg | $98 | 2021-12-16 | Buy |
| Ambeed | A277387 | N-(4-(2-Methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamidehydrochloride 98+% | 100mg | $98 | 2021-12-16 | Buy |
| Ambeed | A277387 | N-(4-(2-Methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamidehydrochloride 98+% | 1g | $833 | 2021-12-16 | Buy |
| Ambeed | A277387 | N-(4-(2-Methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamidehydrochloride 98+% | 5g | $833 | 2021-12-16 | Buy |
| ApexBio Technology | A8402 | ConivaptanHCl | 10mg | $77 | 2021-12-16 | Buy |
| ApexBio Technology | A8402 | ConivaptanHCl | 10mM(in 1mL DMSO) | $88 | 2021-12-16 | Buy |
| Arctom | AS504271 | Conivaptanhydrochloride ≥98% | 5mg | $15 | 2021-12-16 | Buy |
| Arctom | AS504271 | Conivaptanhydrochloride ≥98% | 10mg | $20 | 2021-12-16 | Buy |
| Arctom | AS504271 | Conivaptanhydrochloride ≥98% | 50mg | $34 | 2021-12-16 | Buy |
| Arctom | AS504271 | Conivaptanhydrochloride ≥98% | 100mg | $65 | 2021-12-16 | Buy |
| Arctom | AS504271 | Conivaptanhydrochloride ≥98% | 250mg | $97 | 2021-12-16 | Buy |
| Arctom | AS504271 | Conivaptanhydrochloride ≥98% | 1g | $228 | 2021-12-16 | Buy |
Properties
Melting point :>250°
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
InChIKey :BTYHAFSDANBVMJ-UHFFFAOYSA-N
SMILES :C12=CC=CC=C1N(CCC1N=C(C)NC2=1)C(=O)C1=CC=C(NC(=O)C2C=CC=CC=2C2=CC=CC=C2)C=C1.Cl
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
InChIKey :BTYHAFSDANBVMJ-UHFFFAOYSA-N
SMILES :C12=CC=CC=C1N(CCC1N=C(C)NC2=1)C(=O)C1=CC=C(NC(=O)C2C=CC=CC=2C2=CC=CC=C2)C=C1.Cl
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Arginine vasopressin is intimately involved in volume homeostasis, and elevated levels of arginine vasopressin are responsible for the pathogenesis and progression of diseases with an imbalance of sodium and water, particularly congestive heart failure. To restore homeostasis, antagonism of vasopressin receptors is a practical solution. As such, conivaptan has been developed and launched as a dual V1a and V2 vasopressin receptor antagonist. As a competitive, reversible inhibitor of both subtypes, conivaptan can modulate systemic vascular resistance through the V1a receptor (Ki ? 0.48 nM) distributed in vascular smooth muscle cells, cardiomyocytes, hepatocytes, and platelets and blocks the renal V2 receptor (Ki ? 3.04 nM) resulting in enhanced diuresis, thereby increasing serum sodium concentration and reducing total body volume. Currently, the drug is approved for the management of refractory hyponatremia and potentially lifethreatening sodium and water imbalance, but it has shown promise as a potential treatment option for other diseases, such as congestive heart failure, syndrome of antidiuretic hormone, diabetes insipidus, and liver cirrhosis.More related product prices
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Suppliers and manufacturers
Hefei TianRui Pharmaceutical Chemical Co., Ltd.
Capot Chemical Co.,Ltd.
Henan Tianfu Chemical Co.,Ltd.
Shanghai Yingrui Biopharma Co., Ltd.
Jinan Shengqi pharmaceutical Co,Ltd
Hubei Jusheng Technology Co.,Ltd.
BOC Sciences
Chongqing Chemdad Co., Ltd
