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ChemicalBook >> CAS DataBase List >> Cyproterone acetate

Cyproterone acetate

Cyproterone acetate price.
  • $6 - $875
  • Product name: Cyproterone acetate
  • CAS: 427-51-0
  • MF: C24H29ClO4
  • MW: 416.94
  • EINECS:207-048-3
  • MDL Number:MFCD00864671
  • Synonyms:cyprosteroneacetate ;1,2-alpha-methylene-6-chloro-delta-(sup4,6)-pregnadiene-17-alpha-ol-3,20-dio ;1,2-alpha-methylene-6-chloro-delta(sup6)-17-alpha-hydroxyprogesteroneacetat ;1,2-alpha-methylene-6-chloro-pregna-4,6-diene-3,20-dione17-alpha-acetate ;17-alpha-acetoxy-6-chloro-1-alpha,2-alpha-methylenepregna-4,6-diene-3,20-dio ;20-dione,6-chloro-17-hydroxy-1-alpha,2-alpha-methylene-pregna-6-diene-3 ;6)-pregnadiene-17-alpha-ol-3,20-dione17-2-alpha-methylene-6-chloro-(sup4 ;6-chlor-delta(sup6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteronacetat
33 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • Crysdot
  • CSNpharm
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
Package
  • y0001390
  • 25mg
  • 50mg
  • 100MG
  • 200MG
  • 250MG
  • c3283000
  • 1g
  • 2.5G
  • 5g
  • 10g
  • 25g
  • 50g
  • 100g
  • ManufacturerAHH
  • Product numberMT-49662
  • Product descriptionCyproterone Acetate 97%
  • Packaging5g
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10331
  • Product descriptionCyproterone Acetate
  • Packaging25mg
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0006371
  • Product descriptionCYPROTERONE ACETATE 95.00%
  • Packaging100MG
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0006371
  • Product descriptionCYPROTERONE ACETATE 95.00%
  • Packaging250MG
  • Price$470
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0006371
  • Product descriptionCYPROTERONE ACETATE 95.00%
  • Packaging2.5G
  • Price$875
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8404
  • Product descriptionCyproterone Acetate
  • Packaging250mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS499267
  • Product description(1aR,5aR,5bS,8R,8aS,9aS,9bS,9cS)-8-Acetyl-4-chloro-8a,9b-dimethyl-2-oxo-1a,2,5a,5b,6,7,8,8a,9,9a,9b,9c-dodecahydro-1H-cyclopropa[a]pentaleno[1,2-h]naphthalen-8-ylacetate ≥98%
  • Packaging100mg
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS499267
  • Product description(1aR,5aR,5bS,8R,8aS,9aS,9bS,9cS)-8-Acetyl-4-chloro-8a,9b-dimethyl-2-oxo-1a,2,5a,5b,6,7,8,8a,9,9a,9b,9c-dodecahydro-1H-cyclopropa[a]pentaleno[1,2-h]naphthalen-8-ylacetate ≥98%
  • Packaging250mg
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS499267
  • Product description(1aR,5aR,5bS,8R,8aS,9aS,9bS,9cS)-8-Acetyl-4-chloro-8a,9b-dimethyl-2-oxo-1a,2,5a,5b,6,7,8,8a,9,9a,9b,9c-dodecahydro-1H-cyclopropa[a]pentaleno[1,2-h]naphthalen-8-ylacetate ≥98%
  • Packaging1g
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS499267
  • Product description(1aR,5aR,5bS,8R,8aS,9aS,9bS,9cS)-8-Acetyl-4-chloro-8a,9b-dimethyl-2-oxo-1a,2,5a,5b,6,7,8,8a,9,9a,9b,9c-dodecahydro-1H-cyclopropa[a]pentaleno[1,2-h]naphthalen-8-ylacetate ≥98%
  • Packaging5g
  • Price$62
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS499267
  • Product description(1aR,5aR,5bS,8R,8aS,9aS,9bS,9cS)-8-Acetyl-4-chloro-8a,9b-dimethyl-2-oxo-1a,2,5a,5b,6,7,8,8a,9,9a,9b,9c-dodecahydro-1H-cyclopropa[a]pentaleno[1,2-h]naphthalen-8-ylacetate ≥98%
  • Packaging25g
  • Price$214
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2783
  • Product descriptionCyproterone Acetate
  • Packaging100mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2783
  • Product descriptionCyproterone Acetate
  • Packaging1g
  • Price$169
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC20764
  • Product descriptionCyproterone acetate
  • Packaging5G
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC20764
  • Product descriptionCyproterone acetate
  • Packaging10g
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC20764
  • Product descriptionCyproterone acetate
  • Packaging25g
  • Price$250
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-49662 Cyproterone Acetate 97% 5g $400 2021-12-16 Buy
AK Scientific J10331 Cyproterone Acetate 25mg $38 2021-12-16 Buy
American Custom Chemicals Corporation SHG0006371 CYPROTERONE ACETATE 95.00% 100MG $450 2021-12-16 Buy
American Custom Chemicals Corporation SHG0006371 CYPROTERONE ACETATE 95.00% 250MG $470 2021-12-16 Buy
American Custom Chemicals Corporation SHG0006371 CYPROTERONE ACETATE 95.00% 2.5G $875 2021-12-16 Buy
ApexBio Technology A8404 Cyproterone Acetate 250mg $60 2021-12-16 Buy
Arctom AS499267 (1aR,5aR,5bS,8R,8aS,9aS,9bS,9cS)-8-Acetyl-4-chloro-8a,9b-dimethyl-2-oxo-1a,2,5a,5b,6,7,8,8a,9,9a,9b,9c-dodecahydro-1H-cyclopropa[a]pentaleno[1,2-h]naphthalen-8-ylacetate ≥98% 100mg $6 2021-12-16 Buy
Arctom AS499267 (1aR,5aR,5bS,8R,8aS,9aS,9bS,9cS)-8-Acetyl-4-chloro-8a,9b-dimethyl-2-oxo-1a,2,5a,5b,6,7,8,8a,9,9a,9b,9c-dodecahydro-1H-cyclopropa[a]pentaleno[1,2-h]naphthalen-8-ylacetate ≥98% 250mg $9 2021-12-16 Buy
Arctom AS499267 (1aR,5aR,5bS,8R,8aS,9aS,9bS,9cS)-8-Acetyl-4-chloro-8a,9b-dimethyl-2-oxo-1a,2,5a,5b,6,7,8,8a,9,9a,9b,9c-dodecahydro-1H-cyclopropa[a]pentaleno[1,2-h]naphthalen-8-ylacetate ≥98% 1g $20 2021-12-16 Buy
Arctom AS499267 (1aR,5aR,5bS,8R,8aS,9aS,9bS,9cS)-8-Acetyl-4-chloro-8a,9b-dimethyl-2-oxo-1a,2,5a,5b,6,7,8,8a,9,9a,9b,9c-dodecahydro-1H-cyclopropa[a]pentaleno[1,2-h]naphthalen-8-ylacetate ≥98% 5g $62 2021-12-16 Buy
Arctom AS499267 (1aR,5aR,5bS,8R,8aS,9aS,9bS,9cS)-8-Acetyl-4-chloro-8a,9b-dimethyl-2-oxo-1a,2,5a,5b,6,7,8,8a,9,9a,9b,9c-dodecahydro-1H-cyclopropa[a]pentaleno[1,2-h]naphthalen-8-ylacetate ≥98% 25g $214 2021-12-16 Buy
AvaChem 2783 Cyproterone Acetate 100mg $45 2021-12-16 Buy
AvaChem 2783 Cyproterone Acetate 1g $169 2021-12-16 Buy
Biosynth Carbosynth FC20764 Cyproterone acetate 5G $100 2021-12-16 Buy
Biosynth Carbosynth FC20764 Cyproterone acetate 10g $150 2021-12-16 Buy
Biosynth Carbosynth FC20764 Cyproterone acetate 25g $250 2021-12-16 Buy

Properties

Melting point :200-201°C
Boiling point :528.8°C (rough estimate)
Density :1.0677 (rough estimate)
refractive index :1.4429 (estimate)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Practically insoluble in water, very soluble in methylene chloride, freely soluble in acetone, soluble in methanol, sparingly soluble in anhydrous ethanol.
form :Solid
color :White to Off-White
λmax :281nm(MeOH)(lit.)
Merck :14,2774
InChIKey :UWFYSQMTEOIJJG-KIXORDEXNA-N
SMILES :C[C@@]12C(=CC(=O)[C@@H]3C[C@H]13)C(Cl)=C[C@@]1([H])[C@]3([H])CC[C@@](C(=O)C)(OC(=O)C)[C@@]3(C)CC[C@]21[H] |&1:1,6,8,12,14,18,26,30,r|
EPA Substance Registry System :3'H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 17-(acetyloxy)-6-chloro-1,2-dihydro-, (1.beta.,2.beta.)- (427-51-0)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Cyproterone acetate (CPA) is a synthetic steroid that acts as an antagonist/partial agonist of the androgen receptor (IC50 = 26 nM in humans). Androgen receptor antagonists such as CPA have been shown to have clinical use in androgen-dependent conditions such as prostate cancer, hirsutism, and alopecia. However, high doses of CPA (10 mg/animal/day) can suppress accessory sexual glands and fertility in adult male rats. CPA promotes hepatomitogenic activity and has been reported to induce apoptosis of hepatocytes in rats at 0.3 μM after 72 hours exposure.

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