Decursin
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- $32 - $3432.3
- Product name: Decursin
- CAS: 5928-25-6
- MF: C19H20O5
- MW: 328.36
- EINECS:
- MDL Number:MFCD00272154
- Synonyms:DECURSIN;DECURSINOL ANGELATE;(7S)-7,8-Dihydro-8,8-dimethyl-7-[(3-methyl-2-butenoyl)oxy]-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one;3-Methyl-2-butenoic acid (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester;3-Methyl-2-butenoic acid (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-pyrano[3,2-g]-1-benzopyran-7-yl ester;(7S)-7,8-Dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b′]dipyran-7-yl 3-methyl-2-butenoate;(S)-(+)-decursin;Decursin ((+)-Decursin)
35 prices
Selected condition：
Brand
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerArctom
- Product numberCFN98509
- Product descriptionDecursin ≥98%
- Packaging20mg
- Price$228
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY076356
- Product descriptionDecursin,98%,fromAngelicadecursiva(Miq.)Franch.&Sav. ≥98%
- Packaging10mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3209
- Product descriptionDecursin
- Packaging5mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3209
- Product descriptionDecursin
- Packaging10mg
- Price$209
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3209
- Product descriptionDecursin
- Packaging100mg
- Price$890
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb259187
- Product descriptionDecursin 98%
- Packaging20mg
- Price$391
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb259188
- Product descriptionDecursinol angelate 98%
- Packaging10mg
- Price$408
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb259188
- Product descriptionDecursinol angelate 98%
- Packaging20mg
- Price$527
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb259187
- Product descriptionDecursin 98%
- Packaging100mg
- Price$591.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb572877
- Product descriptionDecursin
- Packaging100mg
- Price$912.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb572877
- Product descriptionDecursin
- Packaging250mg
- Price$1654.1
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb572877
- Product descriptionDecursin
- Packaging1g
- Price$3432.3
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD65599
- Product descriptionDecursin
- Packaging1mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD65599
- Product descriptionDecursin
- Packaging2mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD65599
- Product descriptionDecursin
- Packaging5mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD65599
- Product descriptionDecursin
- Packaging10mg
- Price$300
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Arctom | CFN98509 | Decursin ≥98% | 20mg | $228 | 2021-12-16 | Buy |
| Arctom | SY076356 | Decursin,98%,fromAngelicadecursiva(Miq.)Franch.&Sav. ≥98% | 10mg | $270 | 2021-12-16 | Buy |
| AvaChem | 3209 | Decursin | 5mg | $119 | 2021-12-16 | Buy |
| AvaChem | 3209 | Decursin | 10mg | $209 | 2021-12-16 | Buy |
| AvaChem | 3209 | Decursin | 100mg | $890 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb259187 | Decursin 98% | 20mg | $391 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb259188 | Decursinol angelate 98% | 10mg | $408 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb259188 | Decursinol angelate 98% | 20mg | $527 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb259187 | Decursin 98% | 100mg | $591.6 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb572877 | Decursin | 100mg | $912.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb572877 | Decursin | 250mg | $1654.1 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb572877 | Decursin | 1g | $3432.3 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD65599 | Decursin | 1mg | $50 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD65599 | Decursin | 2mg | $80 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD65599 | Decursin | 5mg | $175 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD65599 | Decursin | 10mg | $300 | 2021-12-16 | Buy |
Properties
Melting point :93-94℃
Boiling point :469.4±45.0 °C(Predicted)
Density :1.24
storage temp. :-20°C
solubility :DMSO: soluble5mg/mL, clear
form :powder
color :white to beige
optical activity :[α]/D +120 to +160°, c = 0.5 in chloroform-d
InChI :InChI=1S/C19H20O5/c1-11(2)7-18(21)23-16-9-13-8-12-5-6-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/t16-/m0/s1
InChIKey :CUKSFECWKQBVED-INIZCTEOSA-N
SMILES :C(O[C@@H]1C(C)(C)OC2=C(C1)C=C1C(=C2)OC(=O)C=C1)(=O)/C=C(/C)\C
Boiling point :469.4±45.0 °C(Predicted)
Density :1.24
storage temp. :-20°C
solubility :DMSO: soluble5mg/mL, clear
form :powder
color :white to beige
optical activity :[α]/D +120 to +160°, c = 0.5 in chloroform-d
InChI :InChI=1S/C19H20O5/c1-11(2)7-18(21)23-16-9-13-8-12-5-6-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/t16-/m0/s1
InChIKey :CUKSFECWKQBVED-INIZCTEOSA-N
SMILES :C(O[C@@H]1C(C)(C)OC2=C(C1)C=C1C(=C2)OC(=O)C=C1)(=O)/C=C(/C)\C
Safety Information
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Description
Decursin is a phytochemical originally isolated from A. gigas with diverse biological activities. It reduces the growth of B16/F10 murine melanoma cells, but not NIH-3T3 fibroblasts, via induction of apoptosis and increased caspase-3 activity when used at concentrations ranging from 40 to 100 μM. In vivo, decursin (10 mg/kg, i.p.) reduces tumor growth in a B16/F10 mouse xenograft model. Decursin inhibits RANKL-induced osteoclast differentiation and decreases fusion and migrations of pre-osteoclasts in vitro and prevents LPS-induced bone erosion in mice. In a mouse model of seizures induced by kainic acid , decursin (20 mg/kg) increases latency to the first electroencephalographic (EEG) discharge and attenuates the intensity and reduces the frequency of seizure discharges in the parietal cortex. Decursin inhibits tube formation and expression of VEGF receptor 2 (VEGFR2) in human retinal microvascular endothelial cells (HRMECs) and human umbilical vein endothelial cells (HUVECs) in vitro and reduces retinal expression of VEGFR2 and neovascularization in rats with diabetes induced by streptozotocin . It also reduces hepatic collagen expression, serum levels of ALT, AST, and ALP, and production of reactive oxygen species (ROS) in a mouse model of CCL4-induced liver fibrosis.Related product price
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