Duloxetine hydrochloride
- $30 - $2709
- Product name: Duloxetine hydrochloride
- CAS: 136434-34-9
- MF: C18H20ClNOS
- MW: 333.88
- EINECS:603-962-5
- MDL Number:MFCD06407958
- Synonyms:LY-248686 HCl;(γS)-N-methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine, hydrochloride (1:1);(+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride;LY-248686 hydrochloride;Duloxetine for system suitability;Duloxetine hydrochloride solution;(S)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine hydrochloride;Methanol( Test Duloxetine HCl, 1.0 mg/mL as free base)
51 prices
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Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Chemtos
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Oakwood
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10MG
- 25mg
- 5MG
- y0001454
- 50mg
- 100mg
- 50
- y0001453
- 10
- 500mg
- 1g
- 5g
- 10g
- 250mg
- 1mL
- 25g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product numberJ10476
- Product description(S)-DuloxetineHCl
- Packaging250mg
- Price$46
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberA558
- Product description(S)-DuloxetineHCl
- Packaging1g
- Price$67
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ98826
- Product description(S)-DuloxetineHCl
- Packaging10g
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ10476
- Product description(S)-DuloxetineHCl
- Packaging5g
- Price$301
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002507
- Product description(S)-DULOXETINE HYDROCHLORIDE 95.00%
- Packaging5MG
- Price$511
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002507
- Product description(S)-DULOXETINE HYDROCHLORIDE 95.00%
- Packaging10MG
- Price$658.55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8421
- Product descriptionDuloxetineHCl
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8421
- Product descriptionDuloxetineHCl
- Packaging10mg
- Price$77
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8421
- Product descriptionDuloxetineHCl
- Packaging100mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2477
- Product descriptionDuloxetine Hydrochloride
- Packaging250mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2477
- Product descriptionDuloxetine Hydrochloride
- Packaging1g
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2477
- Product descriptionDuloxetine Hydrochloride
- Packaging5g
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBD165546
- Product descriptionDuloxetine hydrochloride
- Packaging10mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14317
- Product description(S)-Duloxetine (hydrochloride) ≥98%
- Packaging10mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14317
- Product description(S)-Duloxetine (hydrochloride) ≥98%
- Packaging25mg
- Price$60
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14317
- Product description(S)-Duloxetine (hydrochloride) ≥98%
- Packaging50mg
- Price$100
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | J10476 | (S)-DuloxetineHCl | 250mg | $46 | 2021-12-16 | Buy |
AK Scientific | A558 | (S)-DuloxetineHCl | 1g | $67 | 2021-12-16 | Buy |
AK Scientific | J98826 | (S)-DuloxetineHCl | 10g | $250 | 2021-12-16 | Buy |
AK Scientific | J10476 | (S)-DuloxetineHCl | 5g | $301 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0002507 | (S)-DULOXETINE HYDROCHLORIDE 95.00% | 5MG | $511 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0002507 | (S)-DULOXETINE HYDROCHLORIDE 95.00% | 10MG | $658.55 | 2021-12-16 | Buy |
ApexBio Technology | A8421 | DuloxetineHCl | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
ApexBio Technology | A8421 | DuloxetineHCl | 10mg | $77 | 2021-12-16 | Buy |
ApexBio Technology | A8421 | DuloxetineHCl | 100mg | $130 | 2021-12-16 | Buy |
AvaChem | 2477 | Duloxetine Hydrochloride | 250mg | $45 | 2021-12-16 | Buy |
AvaChem | 2477 | Duloxetine Hydrochloride | 1g | $95 | 2021-12-16 | Buy |
AvaChem | 2477 | Duloxetine Hydrochloride | 5g | $290 | 2021-12-16 | Buy |
Biosynth Carbosynth | BD165546 | Duloxetine hydrochloride | 10mg | $55 | 2021-12-16 | Buy |
Cayman Chemical | 14317 | (S)-Duloxetine (hydrochloride) ≥98% | 10mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 14317 | (S)-Duloxetine (hydrochloride) ≥98% | 25mg | $60 | 2024-03-01 | Buy |
Cayman Chemical | 14317 | (S)-Duloxetine (hydrochloride) ≥98% | 50mg | $100 | 2024-03-01 | Buy |
Properties
Melting point :118-122°C
Flash point :9℃
storage temp. :room temp
solubility :H2O: soluble5mg/mL (clear solution, warmed)
pka :pKa in DMF-water (66:34): 9.6(at 25℃)
form :powder
color :white to beige
optical activity :[α]/D +116 to +125°, c = 1 in methanol
Merck :14,3465
InChI :InChI=1/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/s3
InChIKey :BFFSMCNJSOPUAY-VOPAOICTNA-N
SMILES :C1(=CC=CS1)[C@H](CCNC)OC1=CC=CC2=CC=CC=C12.Cl |&1:5,r|
Flash point :9℃
storage temp. :room temp
solubility :H2O: soluble5mg/mL (clear solution, warmed)
pka :pKa in DMF-water (66:34): 9.6(at 25℃)
form :powder
color :white to beige
optical activity :[α]/D +116 to +125°, c = 1 in methanol
Merck :14,3465
InChI :InChI=1/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/s3
InChIKey :BFFSMCNJSOPUAY-VOPAOICTNA-N
SMILES :C1(=CC=CS1)[C@H](CCNC)OC1=CC=CC2=CC=CC=C12.Cl |&1:5,r|
Safety Information
Symbol(GHS): | |||||||||||||||
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Signal word: | Warning | ||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
(S)-Duloxetine is a potent inhibitor of serotonin and norepinephrine reuptake (Kis = 4.6 and 15.6 nM, respectively, for rat synaptosomes). It less effectively inhibits dopamine reuptake (Ki = 369 nM). It is effective in cells, tissues, and in vivo. (S)-Duloxetine has applications in many chronic medical conditions, including major depressive disorder, generalized anxiety disorder, chronic neuropathic and musculoskeletal pain, and fibromyalgia.More related product prices
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Suppliers and manufacturers
Shanghai Time Chemicals CO., Ltd.
Lianyungang happen teng technology co., LTD